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MMP-16/MT3-MMP Antibody (782005) [DyLight 680]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
782005
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 680

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MMP-16/MT3-MMP Antibody (782005) [DyLight 680] Summary

Immunogen
Chinese hamster ovary cell line CHO-derived recombinant human MMP-16/MT3-MMP
Ala32-Pro535
Accession # P51512
Specificity
Detects human MMP-16/MT3-MMP in ELISAs. In direct ELISAs, no cross-reactivity with recombinant human MMP-14, -15, or -24 is observed.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
MMP16
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for MMP-16/MT3-MMP Antibody (782005) [DyLight 680]

  • chromosome 8 open reading frame 57
  • DKFZp761D112
  • EC 3.4.24
  • EC 3.4.24.-
  • EC 3.4.24.80
  • matrix metallopeptidase 16 (membrane-inserted)
  • matrix metalloproteinase 16 (membrane-inserted)
  • matrix metalloproteinase-16
  • Membrane-type matrix metalloproteinase 3
  • Membrane-type-3 matrix metalloproteinase
  • MMP16
  • MMP-16
  • MMPX2
  • MMP-X2
  • MT3MMP
  • MT3-MMP
  • MT3-MMPC8orf57
  • MT-MMP 3
  • MT-MMP2
  • MTMMP3
  • MT-MMP3
  • Putative transmembrane protein C8orf57

Background

The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-13 (also designated collagenase-3) is produced by breast carcinomas and degrades collagen types I, II and III. MMP-13 has wide substrate specificity, and its physiologic expression is limited to situations in which rapid and effective remodeling of collagenous ECM takes place, such as fetal bone development and adult bone remodeling.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol MMP16