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MGMT Antibody (OTI4F9) [DyLight 594]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clone
OTI4F9
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 594

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-72659AF350
Alexa Fluor 405
NBP2-72659AF405
Alexa Fluor 488
NBP2-72659AF488
Alexa Fluor 532
NBP2-72659AF532
Alexa Fluor 594
NBP2-72659AF594
Alexa Fluor 647
NBP2-72659AF647
Alexa Fluor 700
NBP2-72659AF700
Alexa Fluor 750
NBP2-72659AF750
Allophycocyanin
NBP2-72659APC
Biotin
NBP2-72659B
CoraFluor 1
NBP2-72659CL1
DyLight 350
NBP2-72659UV
DyLight 405
NBP2-72659V
DyLight 488
NBP2-72659G
DyLight 550
NBP2-72659R
DyLight 650
NBP2-72659C
DyLight 680
NBP2-72659FR
DyLight 755
NBP2-72659IR
FITC
NBP2-72659F
HRP
NBP2-72659H
Janelia Fluor 525
NBP2-72659JF525
Janelia Fluor 549
NBP2-72659JF549
Janelia Fluor 585
NBP2-72659JF585
Janelia Fluor 635
NBP2-72659JF635
Janelia Fluor 646
NBP2-72659JF646
Janelia Fluor 669
NBP2-72659JF669
PE
NBP2-72659PE
PerCP
NBP2-72659PCP
Unconjugated
NBP2-45843
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-45843
Azide and BSA Free
NBP2-72659
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MGMT Antibody (OTI4F9) [DyLight 594] Summary

Immunogen
Full length recombinant protein of human MGMT (NP_002403) produced in HEK293T cells.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
MGMT
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for MGMT Antibody (OTI4F9) [DyLight 594]

  • 6-O-methylguanine-DNA methyltransferase
  • EC 2.1.1.63
  • methylated-DNA--protein-cysteine methyltransferase
  • methylguanine-DNA methyltransferase
  • MGMT
  • O-6-methylguanine-DNA methyltransferase
  • O6-methylguanine-DNA methyltransferase
  • O-6-methylguanine-DNA-alkyltransferase

Background

O6-Methylguanine-DNA Methyltransferase (MGMT) is an important DNA repair protein involved in tumor cell resistance to the cytotoxic activity of chemotherapeutic alkylating agents. This protein is also effective in protecting normal cells against the genotoxic and carcinogenic effects of DNA alkylation. The alkylating drug resistance is caused by MGMT's ability to remove DNA alkyl groups introduced in the O6 position of guanine. MGMT is expressed in highly variable amounts, depending upon the cell and tissue type, species, and cellular growth characteristics. In addition, MGMT activity varies among groups of tumors and within a particular type of tumor.

MGMT antibodes are useful tools for DNA repair studies and for some cancer research.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol MGMT