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mGluR6 Antibody [CoraFluor™ 1]

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Product Details

Summary
Reactivity Mu, RtSpecies Glossary
Applications WB, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
CoraFluor 1

Order Details

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mGluR6 Antibody [CoraFluor™ 1] Summary

Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
Immunogen
C-terminus of rat metabotropic Glutamate Receptor 6 (mGluR6) [Uniprot: P35349]
Localization
Integral membrane protein.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GRM6
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Reactivity has been poor on human brain tissue.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
No Preservative
Purity
Immunogen affinity purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for mGluR6 Antibody [CoraFluor™ 1]

  • CSNB1B
  • glutamate receptor, metabotropic 6
  • Gm3
  • GPRC1F
  • GPRC1Fmetabotropic glutamate receptor 6
  • GRM6
  • mGlu6
  • mGluR6
  • MGLUR6DKFZp686H1993

Background

Metabotropic Glutamate Receptor 6 (mGluR6) is a member of the G protein-coupled receptor III family, linked to the inhibition of the cyclic AMP cascade. mGluR6 displays the highest sequence similarity to mGluR4 among the metabotropic receptor subtypes and inhibits the forskolin-stimulated cyclic AMP accumulation in CHO cells transfected with the cloned cDNA.

mGluR6 antibodies are most useful for G protein-coupled receptor research and metabolism studies.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Bioinformatics

Gene Symbol GRM6