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MBP Antibody (7G7) [HRP]

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Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Bv, EqSpecies Glossary
Applications WB, ICC/IF, IHC, IP
Clone
7G7
Clonality
Monoclonal
Host
Mouse
Conjugate
HRP
Datasheet
Reviews & Publications
Protocols & FAQs
Support & Research

MBP Antibody (7G7) [HRP] Summary

Immunogen
Purified myelin basic protein isolated from bovine brain, epitope is in peptide TPPPSQGKG, amino acids 125-133 of the human 21.5kDa sequence.
Marker
Oligodendrocyte Marker, Myelin Marker
Specificity
The MBP Antibody (7G7) antibody binds all four of the CNS MBP isoforms, so that the epitope for the antibody is located in the core shared by all four gene products.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
MBP
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

This peptide is invariant in rat, mouse, cow and many other species, so this antibody will have wide applicability. TMW ranges are 14 - 21.5 kDa (rodent) and 17.2 - 21.5 kDa (human).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
No Preservative
Purity
Affinity purified

Alternate Names for MBP Antibody (7G7) [HRP]

  • Hmbpr
  • MBP
  • MGC99675
  • mld
  • Myelin A1 protein
  • myelin basic protein
  • Myelin membrane encephalitogenic protein
  • shi

Background

Myelin Basic Protein (MBP) functions in the nervous system in myelination and is expressed in oligodendrocytes following differentiation. There are numerous isoforms generated by differential splicing events and post-translational modifications that have specialized functions. These functions include participation in signaling pathways prior to myelination, myelination or the re-myelination process following neural injury.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol MBP