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MBP-1 Antibody

Images

 
Western Blot: PRG2 Antibody [NBP2-19928] - Whole cell extract (30 ug) was separated by 12% SDS-PAGE, and the membrane was blotted with PRG2 antibody diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody ...read more
Immunohistochemistry-Paraffin: PRG2 Antibody [NBP2-19928] - Human hepatoma, using PRG2 antibody at 1:500 dilution. Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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MBP-1 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human MBP-1. The exact sequence is proprietary.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PRG2
Purity
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:500-1:3000
Theoretical MW
25 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7), 20% Glycerol
Preservative
0.025% Proclin 300
Purity
Antigen Affinity-purified

Alternate Names for MBP-1 Antibody

  • BMPG
  • BMPGeosinophil major basic protein
  • bone marrow proteoglycan
  • bone-marrow proteoglycan
  • EMBP
  • MBP1
  • MBP-1
  • MBPeosinophil granule major basic protein
  • MGC14537
  • natural killer cell activator
  • PRG2
  • proteoglycan 2 preproprotein
  • Proteoglycan 2
  • proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granulemajor basic protein)

Background

The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol PRG2
Uniprot