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Matriptase/ST14 Antibody (C4)

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Immunohistochemistry-Paraffin: Matriptase/ST14 Antibody (C4) [NBP3-42111] - DAB staining on IHC-P; Samples: Human Kidney Tissue; Primary Ab: 20ug/ml NBP3-42111; Second Ab: 2ug/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
Immunohistochemistry-Paraffin: Matriptase/ST14 Antibody (C4) [NBP3-42111] - DAB staining on IHC-P; Samples: Human Kidney Tissue; Primary Ab: 20ug/ml NBP3-42111; Second Ab: 2ug/mL HRP-Linked Caprine Anti-Mouse IgG ...read more
Western Blot: Matriptase/ST14 Antibody (C4) [NBP3-42111] - Sample: Recombinant Matriptase/ST14, Human.
Immunohistochemistry-Paraffin: Matriptase/ST14 Antibody (C4) [NBP3-42111] - DAB staining on IHC-P; Samples: Human Stomach Tissue; Primary Ab: 20ug/ml NBP3-42111; Second Ab: 2ug/mL HRP-Linked Caprine Anti-Mouse IgG ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clone
C4
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

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Matriptase/ST14 Antibody (C4) Summary

Immunogen
Immunized with recombinant Human Matriptase/ST14 (Uniprot#: Q9Y5Y6; Arg607-Asn852 (Uniprot#: Q9Y5Y6)
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
ST14
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 5-20ug/mL
  • Western Blot 0.5-2ug/mL

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
0.01M PBS, pH7.4, 50% glycerol
Preservative
0.05% Proclin 300
Concentration
1 mg/ml
Purity
Protein A or G purified

Alternate Names for Matriptase/ST14 Antibody (C4)

  • EC 3.4.21
  • Epithin
  • HAI
  • Matriptase
  • Membrane-type serine protease 1
  • MTSP1
  • MT-SP1EC 3.4.21.109
  • prostamin
  • PRSS14
  • Serine protease 14
  • Serine protease TADG-15
  • SNC19
  • SNC19MTSP1
  • ST14
  • suppression of tumorigenicity 14 (colon carcinoma)
  • suppression of tumorigenicity 14 (colon carcinoma, matriptase, epithin)
  • suppressor of tumorigenicity 14 protein
  • TADG15
  • TADG-15
  • TMPRSS14
  • tumor associated differentially expressed gene 15 protein
  • Tumor-associated differentially-expressed gene 15 protein

Background

ST14 is encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Matriptase/ST14
Antibody (C4)
NBP3-42111
Matriptase/ST14 Antibody (C4)
Species: Hu
Applications: WB, IHC

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Bioinformatics

Gene Symbol ST14