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Matriptase/ST14 Antibody (416802) [Janelia Fluor® 646]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, CyTOF-ready, Flow
Clone
416802
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 646

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
IC3946U-100UG
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IC3946V-100UG
Alexa Fluor 488
IC3946G-100UG
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FAB3946X
Alexa Fluor 594
IC3946T-100UG
Alexa Fluor 647
IC3946R-100UG
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IC3946N-100UG
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IC3946S-100UG
Allophycocyanin
FAB3946A
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DyLight 350
FAB3946D
DyLight 405
FAB3946E
DyLight 488
FAB3946K
DyLight 550
FAB3946L
DyLight 594
FAB3946M
DyLight 650
FAB3946W
DyLight 680
FAB3946Y
DyLight 755
FAB3946Z
FITC
FAB3946F
HRP
FAB3946H
Janelia Fluor 525
FAB3946JF525
Janelia Fluor 549
FAB3946I
Janelia Fluor 585
FAB3946JF585
Janelia Fluor 635
FAB3946JF635
Janelia Fluor 669
FAB3946JF669
PE
FAB3946P
PerCP
FAB3946C
Unconjugated
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mFluor Violet 450 SE
FAB3946MFV450
mFluor Violet 500 SE
FAB3946MFV500
mFluor Violet 610 SE
FAB3946MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB3946
Carrier Free
MAB3946
Carrier Free
MAB3946-SP
Carrier Free
IC3946V-100UG
Carrier Free
IC3946U-100UG
Carrier Free
IC3946T-100UG
Carrier Free
IC3946S-100UG
Carrier Free
IC3946R-100UG
Carrier Free
IC3946N-100UG
Carrier Free
IC3946G-100UG
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Matriptase/ST14 Antibody (416802) [Janelia Fluor® 646] Summary

Immunogen
E. coli-derived recombinant human Matriptase/ST14 Catalytic Domain
Val615-Val855
Accession # Q9Y5Y6
Specificity
Detects human Matriptase/ST14 Catalytic Domain in direct ELISAs and Western blots.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
ST14
Purity
Protein A or G purified from hybridoma culture supernatant
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Intracellular Staining by Flow Cytometry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Matriptase/ST14 Antibody (416802) [Janelia Fluor® 646]

  • EC 3.4.21
  • Epithin
  • HAI
  • Matriptase
  • Membrane-type serine protease 1
  • MTSP1
  • MT-SP1EC 3.4.21.109
  • prostamin
  • PRSS14
  • Serine protease 14
  • Serine protease TADG-15
  • SNC19
  • SNC19MTSP1
  • ST14
  • suppression of tumorigenicity 14 (colon carcinoma)
  • suppression of tumorigenicity 14 (colon carcinoma, matriptase, epithin)
  • suppressor of tumorigenicity 14 protein
  • TADG15
  • TADG-15
  • TMPRSS14
  • tumor associated differentially expressed gene 15 protein
  • Tumor-associated differentially-expressed gene 15 protein

Background

ST14 is encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Matriptase/ST14 Antibody (416802) [Janelia Fluor® 646]
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Bioinformatics

Gene Symbol ST14