Matriptase/ST14 Antibody (2F4)

This product is produced by and distributed for Abnova, a company based in Taiwan.

The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publication using H00006768-M05	Applications	Species
Sasaroli D, Gimotty PA, Pathak HB et al. Novel surface targets and serum biomarkers from the ovarian cancer vasculature. Cancer Biol Ther. 2011-08-01 [PMID: 21617380]

Array H00006768-M05

• Matriptase/ST14 Antibodies
• Matriptase/ST14 Lysate
• Matriptase/ST14 Protein
• Matriptase/ST14 Proteins and Enzymes
• Matriptase/ST14 ELISA