LSP1 Antibody - BSA Free

Images

 
Western Blot: LSP1 Antibody [NBP1-74048] - Western blot analysis of LSP1 in Ramos (1) and Daudi (2) cell lysates.
Immunohistochemistry-Paraffin: LSP1 Antibody [NBP1-74048] - IHC analysis of LSP1 in mouse colon tissue. Abundant membrane staining is visible in the epithelial cells.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ELISA, IHC, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1.0 mg/ml

Order Details

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LSP1 Antibody - BSA Free Summary

Immunogen
A synthetic peptide corresponding a C-terminal portion of the human LSP1 protein (between amino acids 250-339) [UniProt P33241].
Localization
Cytoplasmic and membrane
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
LSP1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 0.01-0.1 ug/ml
  • Immunohistochemistry 1:200
  • Immunohistochemistry-Paraffin 1:200
  • Immunoprecipitation 2-5 ug/ml
  • Western Blot 1.0 - 2.0 ug/ml
Publications
Read Publication using
NBP1-74048 in the following applications:

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for LSP1 Antibody - BSA Free

  • 47 kDa actin binding protein
  • 47 kDa actin-binding protein
  • 52 kDa phosphoprotein
  • F-actin binding and cytoskeleton associated protein
  • leufactin (leukocyte F-actin binding protein)
  • leukocyte-specific protein 1
  • lymphocyte-specific protein 1
  • lymphocyte-specific protein pp52
  • pp52
  • WP34Lymphocyte-specific antigen WP34

Background

Lymphocyte-specific protein 1 (LSP1), also known as 47 kDa actin-binding protein, 52 kDa phosphoprotein, and Lymphocyte-specific antigen WP34, is an intracellular F-actin binding protein. LSP1 is expressed in lymphocytes, neutrophils, macrophages, and endothelium. LSP1 is also found in activated T-lymphocytes. LSP1 is known to function in neutrophil motility regulation, adhesion to fibrinogen matrix proteins, and trans-endothelial migration. LSP1 is phosphorylated by casein kinase II, protein kinase C and MAPKAPK2. The phosphorylation by protein kinase C induces translocation of LSP1 from the cell membrane to the cytoplasm. Phosphorylation of LSP1 by MAPKAPK2 regulates neutrophil chemotaxis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for LSP1 Antibody (NBP1-74048)(1)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 2 applications: IF/IHC, IHC-P.


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IF/IHC
(1)
IHC-P
(1)
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Mouse
(1)
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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol LSP1
Entrez
Uniprot