Western blot shows lysates of human liver tissue. PVDF Membrane was probed with 2 µg/mL of Human LRP-1 Intracellular Domain Monoclonal Antibody (Catalog # MAB6360) followed by HRP-conjugated Anti-Mouse IgG Secondary ...read more
LRP-1 was detected in immersion fixed HepG2 human hepatocellular carcinoma cell line using Mouse Anti-Human LRP-1 Intracellular Domain Monoclonal Antibody (Catalog # MAB6360) at 3 µg/mL for 3 hours at room temperature. ...read more
LRP‑1 was detected in immersion fixed paraffin-embedded sections of human liver using Mouse Anti-Human LRP‑1 Intracellular Domain Monoclonal Antibody (Catalog # MAB6360) at 5 µg/mL for 1 hour at room ...read more
E. coli-derived recombinant human LRP-1 Gln4449-ala4544 Accession # Q07954
Specificity
Detects human LRP-1 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) LRP‑1 clusters 2, 3, or 4, rhLRP‑4, rhLRP-5, rhLRP-5 intracellular domain, rhLRP-6, rhLRP-6 intracellular domain, or rhLRPAP is observed.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
LRP1
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for LRP-1 Antibody (545503) [Unconjugated]
A2MR
Alpha-2-Macroglobulin Receptor
APOER
Apolipoprotein E receptor
APR
CD91 antigen
CD91
EC 1.1.1.94
EC 3.4.21.9
IGFBP3R
low density lipoprotein receptor-related protein 1
LRP
LRP-1
LRP1A
prolow-density lipoprotein receptor-related protein 1
TbetaR-V/LRP-1/IGFBP-3 receptor
TGFBR5
type V tgf-beta receptor
Background
LRP-1 (low-density lipoprotein receptor-related protein 1) is a large type I transmembrane protein belonging to the LDL receptor superfamily. The extracellular domain of LRP-1 is organized in four clusters of ligand-binding repeats that recognizes at least 30 different ligands. The amino acid sequence of human and mouse LRP-1 cluster II share 100% identity. LRP-1 is an endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. It plays a crucial role in early embryonic development.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.
=
÷
Review this Product
Be the first to review our LRP-1 Antibody (545503) [Unconjugated] and receive a gift card or discount.