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Lipin 2 Antibody [Unconjugated]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
LYOPH

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Lipin 2 Antibody [Unconjugated] Summary

Immunogen
E. coli-derived recombinant human Lipin 2
Ser439-Lys563
Accession # Q92539
Specificity
Detects Lipin 2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human (rh) Lipin 1 and rhLipin 3 is observed.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
LPIN2
Purity Statement
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 0.1 ug/mL
Publications
Read Publication using
AF3756 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Lipin 2 Antibody [Unconjugated]

  • EC 3.1.3.4
  • KIAA0249lipin-2
  • Lipin 2
  • Lipin-2
  • LPIN2
  • phosphatidate phosphatase LPIN2

Background

Human Lipin 2 is a 100 kDa (896 aa) nuclear protein that belongs to the large, evolutionarily conserved Lipin family. All Lipin family members have a conserved N‑lipin domain at the N‑termini, a nuclear localization signal, and a conserved C-lipin domain near the C-termini. The functions of the N- and C-lipin domain are not known. Lipin 2 is widely expressed. Mutations in human Lipin 2 have been associated with autosomal dominant high grade myopia and Majeed syndrome. Over the region used as immunogen, human and mouse Lipin 2 are 100% identical. Lipin 2 also shares approximately 48% - 50% amino acid sequence identity with Lipin 1 and Lipin 3.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Lipin 2 Antibody (AF3756)(1)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 1 application: Western Blot.


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Bioinformatics

Gene Symbol LPIN2
Uniprot