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Lgr5/GPR49 Antibody (707042) [Janelia Fluor® 669]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready, Func, ICC/IF
Clone
707042
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 669

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB8078U-100UG
Alexa Fluor 405
FAB8078V-100UG
Alexa Fluor 488
FAB8078G-100UG
Alexa Fluor 532
FAB8078X
Alexa Fluor 594
FAB8078T-100UG
Alexa Fluor 647
FAB8078R-100UG
Alexa Fluor 700
FAB8078N-100UG
Alexa Fluor 750
FAB8078S-100UG
Allophycocyanin
FAB8078A
Allophycocyanin/Cy7
FAB8078APCCY7
Biotin
FAB8078B
CoraFluor 1
FAB8078CL1
DyLight 350
FAB8078D
DyLight 405
FAB8078E
DyLight 488
FAB8078K
DyLight 550
FAB8078L
DyLight 594
FAB8078M
DyLight 650
FAB8078W
DyLight 680
FAB8078Y
DyLight 755
FAB8078Z
FITC
FAB8078F
HRP
FAB8078H
Janelia Fluor 525
FAB8078JF525
Janelia Fluor 549
FAB8078I
Janelia Fluor 646
FAB8078J
PE/Atto594
FAB8078PEATT594
PE/Cy5.5
FAB8078PECY55
PE/Cy7
FAB8078PECY7
PerCP
FAB8078C
Phycoerythrin
FAB8078P
Unconjugated
MAB8078
mFluor Violet 450 SE
FAB8078MFV450
mFluor Violet 500 SE
FAB8078MFV500
mFluor Violet 610 SE
FAB8078MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB8078
Carrier Free
FAB8078P
Carrier Free
FAB8078A
Carrier Free
MAB8078
Carrier Free
MAB8078-SP
Carrier Free
FAB8078V-100UG
Carrier Free
FAB8078U-100UG
Carrier Free
FAB8078T-100UG
Carrier Free
FAB8078S-100UG
Carrier Free
FAB8078R-100UG
Carrier Free
FAB8078N-100UG
Carrier Free
FAB8078G-100UG
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Lgr5/GPR49 Antibody (707042) [Janelia Fluor® 669] Summary

Additional Information
Published as Clone RD42
Immunogen
Chinese hamster ovary cell line CHO-derived recombinant human Lgr5/GPR49
Met1-Ile560
Accession # O75473
Specificity
Detects human Lgr5/GPR49 in ELISA. Stains human and mouse Lgr5 transfected cells but not irrelevant transfectants in Flow Cytometry and Immunocytochemistry. This antibody, also known as "RD42", has been found to detect an epitope in C-terminal LRR cap of LGR5 (Ref. 1).
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
LGR5
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Applications/Dilutions

Dilutions
  • Agonist Activity
  • CyTOF-ready
  • Flow Cytometry
  • Immunocytochemistry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Lgr5/GPR49 Antibody (707042) [Janelia Fluor® 669]

  • FEX
  • G protein-coupled receptor 49
  • GPR49
  • GPR49G-protein coupled receptor HG38
  • GPR67
  • G-protein coupled receptor 49
  • G-protein coupled receptor 67
  • GRP49
  • HG38
  • leucine-rich repeat containing G protein-coupled receptor 5
  • leucine-rich repeat-containing G protein-coupled receptor 5
  • leucine-rich repeat-containing G-protein coupled receptor 5
  • Lgr5
  • MGC117008
  • orphan G protein-coupled receptor HG38

Background

Leucine-rich repeat-containing LGR5, also known as GPR49, is an Orphan-A G-protein coupled receptor with an unknown ligand. GPR49 is a stem cell marker of the intestinal epithelium and the hair follicule, and is often expressed in the brain, skeletal muscle, placenta, and spinal cord. Because LGR5 is typically found in mouse hair follicles it may potentially be used to regrow hair in mice. GPR49/LGR5 antibodies are useful tools for research on hair loss and hair follicule development.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Lgr5/GPR49
Antibody (707042) [Ja ...
FAB8078JF669
Lgr5/GPR49 Antibody (707042) [Janelia Fluor® 669]
Species: Hu
Applications: Flow, CyTOF-ready, Func, ICC/IF

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Bioinformatics

Gene Symbol LGR5