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Leucyl-cystinyl Aminopeptidase/LNPEP Antibody [Alexa Fluor® 647]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Alexa Fluor 647

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Leucyl-cystinyl Aminopeptidase/LNPEP Antibody [Alexa Fluor® 647] Summary

Immunogen
LNPEP antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human LNPEP. The immunogen is located within amino acids 900 - 950 of LNPEP. Amino Acid Squence: SLNGDNFRTQKLSFI
Specificity
At least three isoforms are known to exist; this antibody will detect all three isoforms. Despite its predicted molecular weight, Leucyl-cystinyl Aminopeptidase/LNPEP often migrates at 165kD in SDS-PAGE.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
LNPEP
Purity
Peptide affinity purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Peptide affinity purified

Notes



Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Leucyl-cystinyl Aminopeptidase/LNPEP Antibody [Alexa Fluor® 647]

  • angiotensin IV receptor
  • AT (4) receptor
  • CAP
  • Cystinyl aminopeptidase
  • EC 3.4.11
  • EC 3.4.11.3
  • Insulin-regulated membrane aminopeptidase
  • Insulin-responsive aminopeptidase
  • IRAP
  • leucyl/cystinyl aminopeptidase
  • Leucylcystinyl Aminopeptidase
  • Leucyl-cystinyl Aminopeptidase
  • LNPEP
  • Otase
  • Oxytocinase
  • Placental leucine aminopeptidase
  • PLAP
  • P-LAP
  • P-LAPinsulin-regulated aminopeptidase
  • Vasopressinase

Background

Alkaline phosphatases are phosphodiesterases. The placental-specific isozyme of Alkaline Phosphatase (PLAP) is found in trophoblast cells of normal human mature placenta, seminomas of testis and ovarian carcinomas. Detection of alkaline phosphatase in serum is a marker for ovarian and testicular cancer. This antibody reacts with a membrane-bound isoenzyme of placental alkaline phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation. It is useful in the identification of testicular germ cell tumors. Unlike germ cell tumors, PLAP-positive somatic cell tumors uniformly express epithelial membrane antigen (EMA).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol LNPEP