This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
Alternate Names for KLRC1/2/3 Antibody (20d5) [PE]
CD159 antigen-like family member A
CD159a antigen
CD159a
C-lectin type II protein
killer cell lectin-like receptor subfamily C, member 1
MGC13374
natural killer cell lectin
natural killer group protein 2
NK cell receptor A
NKG2
NKG2-1/B activating NK receptor
NKG2-A
NKG2-A/B type II integral membrane protein
NKG2-A/B-activating NK receptor
NKG2-A/NKG2-B type II integral membrane protein
NKG2AMGC59791
NKG2-B
Background
The monoclonal antibody 20d5 reacts with an epitope common to the NKG2A, NKG2C and NKG2E isoforms of the CD94/NKG2 heterodimer, a member of the c-type lectin family of inhibitory receptors. Mouse CD94/NKG2 is a natural killer (NK) cell receptor for the non-classical MHC class I molecule Qa-1b. (2, 3) NKG2 is expressed on NK cells, lymphokine-activated killer (LAK) T cells, and some CD8+ memory T cells. Two-color immunofluorescent staining with the 20d5 antibody reveals two distinct NKG2+ phenotypes within the NK1.1+CD3- spleen cell population: NKG2hi (50%) and NKG2low (50%). With the exception of DBA/2J mice, NKG2 is expressed on NK1.1+ cells from all mouse strains tested (C57BL/6, BALB/c, 129/J, C3H.SW, AKR/J, SJL). (1)
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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