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KIR2DL1/KIR2DS5 Antibody (143211) [Allophycocyanin]

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Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human KIR2DL1/KIR2DS5 APC-conjugated Monoclonal Antibody (Catalog # FAB1844A) and Mouse Anti-Human NCAM-1/CD56 PE-conjugated Monoclonal ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
143211
Clonality
Monoclonal
Host
Mouse
Conjugate
Allophycocyanin

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KIR2DL1/KIR2DS5 Antibody (143211) [Allophycocyanin] Summary

Immunogen
BaF3 mouse pro-B cell line transfected with human KIR2DL1/KIR2DS5
Accession # P43626
Specificity
Detects human KIR2DL1/KIR2DS5 on transfected cells. It does not stain cells transfected with KIR2DL2, 2DL3, 2DL4, 2DL5, 2DS1, 2DS2, 2DS4, 3DL1, 3DL2, or 3DS1.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
KIR2DL1
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells
Publications
Read Publications using
FAB1844A in the following applications:

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for KIR2DL1/KIR2DS5 Antibody (143211) [Allophycocyanin]

  • CD158a
  • KIR2DL1/KIR2DS5

Background

KIR2DL1 is one of several immunoglobulin-like receptors expressed on NK cells that bind MHC class I molecules and transmit inhibitory signals. KIR2DL1 is specific for HLA-C alleles with Asn77 and Lys80.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for KIR2DL1/KIR2DS5 Antibody (FAB1844A)(9)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: Flow Cytometry.


Filter By Application
Flow Cytometry
(7)
All Applications
Filter By Species
Human
(7)
All Species
Showing Publications 1 - 9 of 9.
Publications using FAB1844A Applications Species
Mai Anh Thi Nguyen, Kohei Hosokawa, Takeshi Yoroidaka, Hiroyuki Maruyama, J. Luis Espinoza, Mahmoud I. Elbadry et al. Resistance of KIR Ligand–Missing Leukocytes to NK Cells In Vivo in Patients with Acquired Aplastic Anemia ImmunoHorizons 7/1/2020 [PMID: 32680908]
Todd Bradley, Dimitra Peppa, Isabela Pedroza-Pacheco, Dapeng Li, Derek W. Cain, Ricardo Henao et al. RAB11FIP5 Expression and Altered Natural Killer Cell Function Are Associated with Induction of HIV Broadly Neutralizing Antibody Responses Cell 10/4/2018 [PMID: 30270043]
NK Cell Responses to Human Tick-Borne Encephalitis Virus Infection J Immunol, 2016-08-19;0(0):. 2016-08-19 [PMID: 27543616] (Flow Cytometry, Human) Flow Cytometry Human
Marquardt N, Beziat V, Nystrom S, Hengst J, Ivarsson M, Kekalainen E, Johansson H, Mjosberg J, Westgren M, Lankisch T, Wedemeyer H, Ellis E, Ljunggren H, Michaelsson J, Bjorkstrom N Cutting edge: identification and characterization of human intrahepatic CD49a+ NK cells. J Immunol, 2015-02-11;194(6):2467-71. 2015-02-11 [PMID: 25672754] (Flow Cytometry, Human) Flow Cytometry Human
Killig M, Friedrichs B, Meisig J, Gentilini C, Bluthgen N, Loddenkemper C, Labopin M, Basara N, Pfrepper C, Niederwieser D, Uharek L, Romagnani C Tracking in vivo dynamics of NK cells transferred in patients undergoing stem cell transplantation. Eur J Immunol, 2014-06-30;44(9):2822-34. 2014-06-30 [PMID: 24895051] (Flow Cytometry, Human) Flow Cytometry Human
Charoudeh H, Terszowski G, Czaja K, Gonzalez A, Schmitter K, Stern M Modulation of the natural killer cell KIR repertoire by cytomegalovirus infection. Eur J Immunol, 2012-12-12;43(2):480-7. 2012-12-12 [PMID: 23161492] (Flow Cytometry, Human) Flow Cytometry Human
Beziat V, Dalgard O, Asselah T, Halfon P, Bedossa P, Boudifa A, Hervier B, Theodorou I, Martinot M, Debre P, Bjorkstrom NK, Malmberg KJ, Marcellin P, Vieillard V CMV drives clonal expansion of NKG2C+ NK cells expressing self-specific KIRs in chronic hepatitis patients. Eur. J. Immunol., 2011-12-16;42(2):447-57. 2011-12-16 [PMID: 22105371] (Flow Cytometry, Human) Flow Cytometry Human
Beziat V, Descours B, Parizot C, Debre P, Vieillard V NK cell terminal differentiation: correlated stepwise decrease of NKG2A and acquisition of KIRs. PLoS ONE, 2010-08-06;5(8):e11966. 2010-08-06 [PMID: 20700504] (Flow Cytometry, Human) Flow Cytometry Human
Alici E, Sutlu T, Bjorkstrand B, Gilljam M, Stellan B, Nahi H, Quezada HC, Gahrton G, Ljunggren HG, Dilber MS Autologous antitumor activity by NK cells expanded from myeloma patients using GMP-compliant components. Blood, 2008-01-11;111(6):3155-62. 2008-01-11 [PMID: 18192509] (Flow Cytometry, Human) Flow Cytometry Human

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol KIR2DL1
Uniprot