Western Blot: KIF1C Antibody [NBP1-85978] - Analysis in human cell line HeLa.
Immunohistochemistry-Paraffin: KIF1C Antibody [NBP1-85978] - Staining of human heart muscle shows strong cytoplasmic positivity in cardiomyocytes.
Immunohistochemistry-Paraffin: KIF1C Antibody [NBP1-85978] - Stain ing of human tonsil shows low positivity in non-germinal center cells as expected.
Immunohistochemistry-Paraffin: KIF1C Antibody [NBP1-85978] - Staining of human skeletal muscle shows moderate cytoplasmic positivity in myocytes.
Immunohistochemistry-Paraffin: KIF1C Antibody [NBP1-85978] - Staining of human kidney shows weak to moderate cytoplasmic positivity in cells in tubules.
Immunohistochemistry-Paraffin: KIF1C Antibody [NBP1-85978] - Staining of human small intestine shows moderate cytoplasmic positivity in glandular cells.
This antibody was developed against Recombinant Protein corresponding to amino acids: SGEAPTPLQPPEEVTPHPATPARRPPSPRRSHHPRRNSLDGGGRSRGAGSAQPEPQHFQPKKHNSYPQPPQPYPAQRPPGPRYPPYTTPPRMRRQRSAPDL
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
KIF1C
Purity
Immunogen affinity purified
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Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified
Alternate Names for KIF1C Antibody
KIAA0706
kinesin family member 1C
kinesin-like protein KIF1C
LTXS1
Background
The kinesin superfamily of proteins consists of over forty KIF motor proteins that function in intracellular transport along microtubules. Kinesin activity has been linked to various cellular functions such as vesicle transport, mitotic spindle formation, chromosome segregation, and cytokinesis. Structurally, all kinesins contain a motor domain with microtubule and nucleotide binding sites that utilize ATP to target cargo along microtubule filaments. KIF1C, also known as LTXS1 (lethal toxin sensitivity), has been found to be localized to the golgi and the endoplasmic reticulum (ER) and play a role in vesicle transport between the golgi and ER. Alternate identifiers of KIF1C include kinesin family member 1C, kinesin-like protein KIF1C and KIAA0706.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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