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JAB1 Antibody (OTI2B12) [Janelia Fluor® 669]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ICC/IF, IHC
Clone
OTI2B12
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 669

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-71659AF350
Alexa Fluor 405
NBP2-71659AF405
Alexa Fluor 488
NBP2-71659AF488
Alexa Fluor 532
NBP2-71659AF532
Alexa Fluor 594
NBP2-71659AF594
Alexa Fluor 647
NBP2-71659AF647
Alexa Fluor 700
NBP2-71659AF700
Alexa Fluor 750
NBP2-71659AF750
Allophycocyanin
NBP2-71659APC
Biotin
NBP2-71659B
CoraFluor 1
NBP2-71659CL1
DyLight 350
NBP2-71659UV
DyLight 405
NBP2-71659V
DyLight 488
NBP2-71659G
DyLight 550
NBP2-71659R
DyLight 594
NBP2-71659DL594
DyLight 650
NBP2-71659C
DyLight 680
NBP2-71659FR
DyLight 755
NBP2-71659IR
FITC
NBP2-71659F
HRP
NBP2-71659H
Janelia Fluor 525
NBP2-71659JF525
Janelia Fluor 549
NBP2-71659JF549
Janelia Fluor 585
NBP2-71659JF585
Janelia Fluor 635
NBP2-71659JF635
Janelia Fluor 646
NBP2-71659JF646
PE
NBP2-71659PE
PerCP
NBP2-71659PCP
Unconjugated
NBP2-01813
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-01813
Azide and BSA Free
NBP2-71659
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JAB1 Antibody (OTI2B12) [Janelia Fluor® 669] Summary

Immunogen
Full length human recombinant protein of human COPS5(NP_006828) produced in HEK293T cell.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
COPS5
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for JAB1 Antibody (OTI2B12) [Janelia Fluor® 669]

  • COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)
  • COP9 signalosome complex subunit 5
  • COPS5
  • CSN5
  • CSN5COP9 (constitutive photomorphogenic, Arabidopsis, homolog) subunit 5
  • EC 3.4
  • JAB1
  • JAB138 kDa Mov34 homolog
  • Jun activation domain-binding protein 1
  • MOV-34
  • SGN5
  • SGN5MGC3149
  • Signalosome subunit 5

Background

The protein encoded by the JAB1 gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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JAB1 Antibody
(OTI2B12) [Janelia Fl ...
NBP2-71659JF669
JAB1 Antibody (OTI2B12) [Janelia Fluor® 669]
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC

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Bioinformatics

Gene Symbol COPS5