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Integrin alpha 2b/CD41 Antibody (745201) [Phycoerythrin]

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Product Details

Summary
Applications Flow
Clone
745201
Clonality
Monoclonal
Host
Mouse
Conjugate
Phycoerythrin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB7616U-100UG
Alexa Fluor 405
FAB7616V-100UG
Alexa Fluor 488
FAB7616G-100UG
Alexa Fluor 532
FAB7616X
Alexa Fluor 594
FAB7616T-100UG
Alexa Fluor 647
FAB7616R-100UG
Alexa Fluor 700
FAB7616N-100UG
Alexa Fluor 750
FAB7616S-100UG
Allophycocyanin
FAB7616A
Allophycocyanin/Cy7
FAB7616APCCY7
Biotin
FAB7616B
CoraFluor 1
FAB7616CL1
DyLight 350
FAB7616D
DyLight 405
FAB7616E
DyLight 488
FAB7616K
DyLight 550
FAB7616L
DyLight 594
FAB7616M
DyLight 650
FAB7616W
DyLight 680
FAB7616Y
DyLight 755
FAB7616Z
FITC
FAB7616F
HRP
FAB7616H
Janelia Fluor 525
FAB7616JF525
Janelia Fluor 549
FAB7616I
Janelia Fluor 646
FAB7616J
Janelia Fluor 669
FAB7616JF669
PE/Atto594
FAB7616PEATT594
PE/Cy5.5
FAB7616PECY55
PE/Cy7
FAB7616PECY7
PerCP
FAB7616C
Unconjugated
MAB7616
mFluor Violet 450 SE
FAB7616MFV450
mFluor Violet 500 SE
FAB7616MFV500
mFluor Violet 610 SE
FAB7616MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB7616
Carrier Free
MAB7616
Carrier Free
FAB7616A
Carrier Free
MAB7616-SP
Carrier Free
FAB7616V-100UG
Carrier Free
FAB7616U-100UG
Carrier Free
FAB7616T-100UG
Carrier Free
FAB7616S-100UG
Carrier Free
FAB7616R-100UG
Carrier Free
FAB7616N-100UG
Carrier Free
FAB7616G-100UG
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Integrin alpha 2b/CD41 Antibody (745201) [Phycoerythrin] Summary

Immunogen
heterodimer of human Integrin alpha 2B (Leu32-Arg993; R887L) Accession P08514 + human Integrin beta 3 (Gly27-Asp718) Accession P05106
Specificity
Detects human Integrin alpha 2b/CD41 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human Integrin alpha 5, alpha 8, alpha V, beta 3, beta 5, beta 6, recombinant mouse Integrin beta 2b or beta 3 is observed.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
ITGA2B
Purity Statement
Protein A or G purified from hybridoma culture supernatant
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Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

Integrin alpha 2b (ITGA2b), also known as CD41 and GPIIb, is a transmembrane glycoprotein that is expressed by megakaryocytes and platelets. It is cleaved into two disulfide-linked chains (114 kDa and 22 kDa) during transit through the Golgi. Integrin alpha 2b associates with Integrin beta 3 to form complexes that interact with Fibrinogen, von Willebrand factor, Fibronectin, and Vitronectin. Integrin alpha 2b is required for platelet aggregation, and defects lead to disorders of coagulation. Within the extracellular domain, human Integrin alpha 2b shares 80% and 78% amino acid sequence identity with mouse and rat Integrin alpha 2b, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Integrin alpha
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FAB7616P
Integrin alpha 2b/CD41 Antibody (745201) [Phycoerythrin]
Species: Hu
Applications: Flow

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Bioinformatics

Gene Symbol ITGA2B