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Integrin alpha 2b/CD41 Antibody (386629) [PerCP]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow, CyTOF-ready, ICC/IF
Clone
386629
Clonality
Monoclonal
Host
Rat
Conjugate
PerCP

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB41181U-100UG
Alexa Fluor 405
FAB41181V-100UG
Alexa Fluor 488
FAB41181G-100UG
Alexa Fluor 532
FAB41181X
Alexa Fluor 594
FAB41181T-100UG
Alexa Fluor 647
FAB41181R-100UG
Alexa Fluor 700
FAB41181N-100UG
Alexa Fluor 750
FAB41181S-100UG
Allophycocyanin
FAB41181A
Allophycocyanin/Cy7
FAB41181APCCY7
Biotin
FAB41181B
CoraFluor 1
FAB41181CL1
DyLight 350
FAB41181D
DyLight 405
FAB41181E
DyLight 488
FAB41181K
DyLight 550
FAB41181L
DyLight 594
FAB41181M
DyLight 650
FAB41181W
DyLight 680
FAB41181Y
DyLight 755
FAB41181Z
HRP
FAB41181H
Janelia Fluor 525
FAB41181JF525
Janelia Fluor 549
FAB41181I
Janelia Fluor 585
FAB41181JF585
Janelia Fluor 635
FAB41181JF635
Janelia Fluor 646
FAB41181J
Janelia Fluor 669
FAB41181JF669
PE/Atto594
FAB41181PEATT594
PE/Cy5.5
FAB41181PECY55
PE/Cy7
FAB41181PECY7
Unconjugated
MAB41181
mFluor Violet 450 SE
FAB41181MFV450
mFluor Violet 500 SE
FAB41181MFV500
mFluor Violet 610 SE
FAB41181MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB41181
Carrier Free
MAB41181
Carrier Free
MAB41181-SP
Carrier Free
FAB41181V-100UG
Carrier Free
FAB41181U-100UG
Carrier Free
FAB41181T-100UG
Carrier Free
FAB41181S-100UG
Carrier Free
FAB41181R-100UG
Carrier Free
FAB41181N-100UG
Carrier Free
FAB41181G-100UG
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Integrin alpha 2b/CD41 Antibody (386629) [PerCP] Summary

Immunogen
Chinese hamster ovary cell line CHO-derived recombinant mouse Integrin alpha 2b/CD41
Leu32-Arg988
Accession # NP_034705
Specificity
Detects mouse Integrin alpha 2b/CD41 in direct ELISAs.
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
ITGA2B
Purity
Protein A or G purified from hybridoma culture supernatant
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Immunocytochemistry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Alternate Names for Integrin alpha 2b/CD41 Antibody (386629) [PerCP]

  • CD41 antigen
  • CD41
  • CD41BHPA3
  • GP2B
  • GP2Bintegrin alpha-IIb
  • GPalpha IIb
  • GPIIb
  • GTA
  • HPA3
  • Integrin alpha 2b
  • integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigenCD41)
  • integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigenCD41B)
  • ITGA2b
  • ITGAB
  • platelet fibrinogen receptor, alpha subunit
  • Platelet membrane glycoprotein IIb
  • platelet-specific antigen BAK

Background

Integrin alpha 2b (CD41) is a calcium-dependent, noncovalently associated heterodimer and contains a heavy chain (GPIIb alpha) and a light chain (GPIIb beta) linked by a single disulfide bond. The Integrin alpha 2B chain interacts with the Integrin beta 3 subunit/CD61 to form the platelet glycoprotein complex, gpIIb/IIIa. It is expressed on platelets and megakaryocytes. Ligands for the gpIIb/IIIa heterodimer include fibrinogen, von Willebrand factor, fibronectin, vitronectin, and thrombospondin. The gpIIb/IIIa complex is the major Integrin on platelets and is important for platelet adhesion and aggregation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Integrin alpha
2b/CD41 Antibody (386 ...
FAB41181C
Integrin alpha 2b/CD41 Antibody (386629) [PerCP]
Species: Mu
Applications: Flow, CyTOF-ready, ICC/IF

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Bioinformatics

Gene Symbol ITGA2B