Inhibin beta A Antibody (CL15357) - Azide and BSA Free

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Product Details

Summary
Reactivity Hu, RtSpecies Glossary
Applications WB, IHC
Clone
CL15357
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
Azide and BSA Free

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Catalog# & Formulation Size Price

Inhibin beta A Antibody (CL15357) - Azide and BSA Free Summary

Immunogen
This antibody was generated using a recombinant protein sequence of P08476, with the exact immunogen sequence remaining proprietary.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
INHBA
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry : 1:50 - 1:200
  • Immunohistochemistry-Paraffin : 1:50 - 1:200
  • Western Blot : 1 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Lyophilized in 5% Trehalose.
Preservative
0.02% Sodium Azide
Purity
Protein A purified

Alternate Names for Inhibin beta A Antibody (CL15357) - Azide and BSA Free

  • Activin Beta A
  • Activin beta-A chain
  • beta A (activin A, activin AB alpha polypeptide)
  • EDF
  • erythroid differentiation factor
  • Erythroid differentiation protein
  • follicle-stimulating hormone-releasing protein
  • FRP
  • FSH-releasing protein
  • INHBA
  • inhibin beta A chain
  • Inhibin Beta A
  • Inhibin Subunit Beta A
  • inhibin, beta A
  • Inhibin, beta-1

Background

The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol INHBA