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IL6R Antibody (OTI2F4) [Janelia Fluor® 585]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF, IHC
Clone
OTI2F4
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 585

Order Details

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IL6R Antibody (OTI2F4) [Janelia Fluor® 585] Summary

Immunogen
Full length human recombinant protein of human IL6R(NP_000556) produced in HEK293T cell.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
IL6R
Purity
Immunogen affinity purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for IL6R Antibody (OTI2F4) [Janelia Fluor® 585]

  • CD126 antigen
  • CD126
  • gp80
  • IL-6 receptor subunit alpha
  • IL-6R 1
  • IL-6R subunit alpha
  • IL-6R-1
  • IL6RA
  • IL-6RA
  • IL-6R-alpha
  • interleukin 6 receptor alpha subunit
  • interleukin 6 receptor
  • interleukin-6 receptor subunit alpha
  • Membrane glycoprotein 80
  • MGC104991

Background

Interleukin 6 (IL6) is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response. The protein encoded by this gene is a subunit of the receptor complex for IL6. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol IL6R