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IL-11 Antibody (22626) [DyLight 488]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, B/N
Clone
22626
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 488

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB218U
Alexa Fluor 405
FAB218V
Alexa Fluor 488
FAB218G
Alexa Fluor 532
FAB218X
Alexa Fluor 594
FAB218T
Alexa Fluor 647
FAB218R
Alexa Fluor 700
FAB218N
Alexa Fluor 750
FAB218S
Allophycocyanin
FAB218A
Biotin
FAB218B
DyLight 350
FAB218D
DyLight 405
FAB218E
DyLight 550
FAB218L
DyLight 594
FAB218M
DyLight 650
FAB218W
DyLight 680
FAB218Y
DyLight 755
FAB218Z
FITC
FAB218F
HRP
FAB218H
Janelia Fluor 525
FAB218JF525
Janelia Fluor 549
FAB218I
Janelia Fluor 646
FAB218J
Janelia Fluor 669
FAB218JF669
PerCP
FAB218C
Unconjugated
MAB218
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB218
Carrier Free
MAB218
Carrier Free
MAB218-SP
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IL-11 Antibody (22626) [DyLight 488] Summary

Immunogen
E. coli-derived recombinant human IL‑11
Pro22-Leu199
Accession # P20809
Specificity
Detects human IL-11 in direct ELISAs and Western blots. In direct ELISAs and Western blots, 100% cross-reactivity with recombinant mouse IL-11 is observed and no cross-reactivity with recombinant human (rh) IL-6, rhCNTF, rhLIF, rhOSM, rhCLC, or rhCT-1 is observed.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
IL11
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Neutralization
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for IL-11 Antibody (22626) [DyLight 488]

  • Adipogenesis inhibitory factor
  • AGIF
  • AGIFoprelvekin
  • IL11
  • IL-11
  • IL-11Oprelvekin
  • interleukin 11
  • interleukin-11
  • Oprelvekin

Background

Interleukin 11 is a pleiotropic cytokine produced by mesenchymal-derived adherent cells. IL11 shares many functions of IL6 and LIF, including potentiation of megakaryocyte activity, enhancement of human myeloma cell proliferation, and enhancement of hepatic acute phase protein production.Interleukin 11 directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells, and induces megakaryocyte maturation resulting in increased platelet production. Clinically it is used to prevent severe thrombocytopenia and the reduction of the need for platelet transfusion following myelosuppressive chemotherapy.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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CTLA-4
[Unconjugated]
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Species: Hu
Applications: IHC, IHC-P, WB

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Bioinformatics

Gene Symbol IL11