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IL-1 RI Antibody (RM0013-11B7) [DyLight 755]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, IHC
Clone
RM0013-11B7
Clonality
Monoclonal
Host
Rat
Conjugate
DyLight 755

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB110-85471AF350
Alexa Fluor 405
NB110-85471AF405
Alexa Fluor 488
NB110-85471AF488
Alexa Fluor 532
NB110-85471AF532
Alexa Fluor 594
NB110-85471AF594
Alexa Fluor 647
NB110-85471AF647
Alexa Fluor 700
NB110-85471AF700
Alexa Fluor 750
NB110-85471AF750
Allophycocyanin
NB110-85471APC
Biotin
NB110-85471B
CoraFluor 1
NB110-85471CL1
DyLight 350
NB110-85471UV
DyLight 405
NB110-85471V
DyLight 488
NB110-85471G
DyLight 550
NB110-85471R
DyLight 594
NB110-85471DL594
DyLight 650
NB110-85471C
DyLight 680
NB110-85471FR
FITC
NB110-85471F
HRP
NB110-85471H
Janelia Fluor 525
NB110-85471JF525
Janelia Fluor 549
NB110-85471JF549
Janelia Fluor 646
NB110-85471JF646
Janelia Fluor 669
NB110-85471JF669
PE
NB110-85471PE
PerCP
NB110-85471PCP
Unconjugated
NB110-85471
mFluor Violet 450 SE
NB110-85471MFV450
mFluor Violet 500 SE
NB110-85471MFV500
mFluor Violet 610 SE
NB110-85471MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NB110-85471
Azide and BSA Free
NB110-85471-0.025mg
Azide and BSA Free
NB110-85471
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IL-1 RI Antibody (RM0013-11B7) [DyLight 755] Summary

Description
This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
Immunogen
Mouse IL-1 RI (extracellular domain)
Specificity
This is recognizes the extracellular domain of mouse IL1 Receptor 1 Antibody (RM0013-11B7)
Isotype
IgG2
Clonality
Monoclonal
Host
Rat
Gene
IL1R1
Purity
Protein A or G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for IL-1 RI Antibody (RM0013-11B7) [DyLight 755]

  • CD121 antigen-like family member A
  • CD121a antigen
  • CD121a
  • IL-1 RI
  • IL1R
  • IL1R1
  • IL1RI
  • IL-1RI
  • IL1RT1
  • IL-1RT1
  • IL-1RT-1
  • Interleukin 1 Receptor 1
  • interleukin 1 receptor, type I
  • interleukin receptor 1
  • interleukin-1 receptor type 1
  • p80

Background

The Interleukin 1 receptor type I (IL-1R1) belongs to the IL-1 receptor family (1). IL-1R1 binds to IL-1 alpha, IL-1 beta, and interleukin-1 receptor antagonist protein (IL-1RA). IL-1RA regulates IL-1 ligand biological activity by a competitive interaction for IL-1R1. Upon IL-1 stimulation, adaptor molecule MyD88 is first recruited to the IL-1R1-IL1R accessory protein complex, followed by the recruitment of two serine-threonine kinases, IRAK4 and IRAK, and the adaptor protein TRAF6, resulting in activation of the NF-kB pathway (2-3). Stimulation of IL-1R1, leads to activation of the transcription factors NF-B, ATF, and AP-1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol IL1R1