IL-1 RI Antibody (JAMA-147) - BSA Free

IL1 binds antigen CD121a, which is a transmembrane glycoprotein and a member of the immunoglobulin superfamily expressed on T cells, thymocytes, dendritic cells, fibroblasts, vascular endothelial cells, epithelial cells and neural cells. CD121a binds the mature forms of IL1 alpha, IL1 beta, and IL1 Ra proteins. High affinity binding and signaling by the type I IL1 receptor requires CD121a and the accessory protein, IL1 R AcP, which does not bind IL1 alone, but forms a dimer capable of binding IL1. Interleukin 1 (IL1), which has a role as a mediator in inflammation, consists of 2 separate but related proteins, IL1 alpha and IL1 beta. Cell surface receptors for the 2 forms of IL1 are identical. IL1R Type I contains a single membrane spanning segment, a large cytoplasmic region, and an extracellular, IL1 binding portion composed of 3 immunoglobulin like domains.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Images	Ratings	Applications	Species	Date	Details
	4 reviewed by: Verified Customer	IHC-Fr	Mouse	08/07/2018	View Summary Application Immunohistochemistry-Frozen Sample Tested brain and spinal cord,Cultured hippocampal neurons Species Mouse Lot NB120-5738

Array NB100-65865

• IL-1 RI Antibodies
• IL-1 RI Antibody Pairs
• IL-1 RI ELISA Kits
• IL-1 RI Proteins
• IL-1 RI Proteins and Enzymes
• IL-1 RI ELISAs