IL-1 beta/IL-1F2 Antibody [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

IL-1 is a name that designates two pleiotropic cytokines, IL-1 alpha (IL-1F1) and IL-1 beta (IL-1F2, IL1B), which are the products of distinct genes. IL-1 alpha and IL-1 beta are structurally related polypeptides that share approximately 26% amino acid (aa) identity in rat. Both proteins are produced by a wide variety of cells in response to inflammatory agents, infections, or microbial endotoxins. While IL-1 alpha and IL-1 beta are regulated independently, they bind to the same receptor and exert identical biological effects. IL-1 RI binds directly to IL-1 alpha or IL-1 beta and then associates with IL-1 R accessory protein (IL-1 R3/IL-1 R AcP) to form a high-affinity receptor complex that is competent for signal transduction. IL-1 RII has high affinity for IL-1 beta but functions as a decoy receptor and negative regulator of IL-1 beta activity. IL-1ra functions as a competitive antagonist by preventing IL-1 alpha and IL-1 beta from interacting with IL-1 RI. Intracellular cleavage of the IL-1 beta precursor by Caspase-1/ICE is a key step in the inflammatory response. The 17 kDa molecular weight mature rat IL-1 beta shares 90% aa sequence identity with cotton rat and mouse and 67%-78% with canine, equine, feline, human, porcine, and rhesus macaque IL-1 beta . IL-1 beta functions in a central role in immune and inflammatory responses, bone remodeling, fever, carbohydrate metabolism, and GH/IGF-I physiology. IL-1 beta dysregulation is implicated in many pathological conditions including sepsis, rheumatoid arthritis, inflammatory bowel disease, acute and chronic myelogenous leukemia, insulin-dependent diabetes mellitus, atherosclerosis, neuronal injury, and aging-related diseases.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Mouse, Rat.

We have publications tested in 8 applications: ELISA Development, ELISA Development (Capture), ICC, IHC, IHC-Fr, IHC-P, Neutralization, Western Blot.

Showing Publications 1 - 10 of 67. Show All 67 Publications. Collapse Publications.

Publications using AF-501-NA	Applications	Species
Sancho-Alonso, M;Arenas, YM;Izquierdo-Altarejos, P;Martinez-Garcia, M;Llansola, M;Felipo, V; Enhanced Activation of the S1PR2-IL-1?-Src-BDNF-TrkB Pathway Mediates Neuroinflammation in the Hippocampus and Cognitive Impairment in Hyperammonemic Rats International journal of molecular sciences 2023-12-08 [PMID: 38139078] (Western Blot, Rat)	Western Blot	Rat
YW Koo, CS Lim, A Darai, J Lee, W Kim, I Han, GH Kim Shape-memory collagen scaffold combined with hyaluronic acid for repairing intervertebral disc Biomaterials research, 2023-03-29;27(1):26. 2023-03-29 [PMID: 36991502]
Bhujel B, Yang SS, Kim HR et al. An Injectable Engineered Cartilage Gel Improves Intervertebral Disc Repair in a Rat Nucleotomy Model International journal of molecular sciences 2023-02-05 [PMID: 36834559]
T Ikebukuro, T Arima, M Kasamatsu, Y Nakano, Y Tobita, M Uchiyama, Y Terashima, E Toda, A Shimizu, H Takahashi Disulfiram Ophthalmic Solution Inhibited Macrophage Infiltration by Suppressing Macrophage Pseudopodia Formation in a Rat Corneal Alkali Burn Model International Journal of Molecular Sciences, 2023-01-01;24(1):. 2023-01-01 [PMID: 36614177] (IHC, Rat)	IHC	Rat
A Nagayach, R Bhaskar, I Patro Microglia activation and inflammation in hippocampus attenuates memory and mood functions during experimentally induced diabetes in rat Journal of chemical neuroanatomy, 2022-09-08;0(0):102160. 2022-09-08 [PMID: 36089179] (IHC, Rat)	IHC	Rat
Andjela Stekic, Milica Zeljkovic, Marina Zaric Kontic, Katarina Mihajlovic, Marija Adzic, Ivana Stevanovic et al. Intermittent Theta Burst Stimulation Ameliorates Cognitive Deficit and Attenuates Neuroinflammation via PI3K/Akt/mTOR Signaling Pathway in Alzheimer’s-Like Disease Model Frontiers in Aging Neuroscience 2022-05-17 [PMID: 35656538]
María del Mar Fernández‐Arjona, Ana León‐Rodríguez, Jesús M. Grondona, María D. López‐Ávalos Long‐term priming of hypothalamic microglia is associated with energy balance disturbances under diet‐induced obesity Glia 2022-09-01 [PMID: 35603807]
T Xu, X Li, Y Guo, E Uhlin, L Holmberg, S Mitra, D Winn, A Falk, E Sundström Multiple therapeutic effects of human neural stem cells derived from induced pluripotent stem cells in a rat model of post-traumatic syringomyelia EBioMedicine, 2022-02-16;77(0):103882. 2022-02-16 [PMID: 35182996] (IHC, Rat)	IHC	Rat
M Jiang, H Xie, C Zhang, T Wang, H Tian, L Lu, JY Xu, GT Xu, L Liu, J Zhang Enhancing fractalkine/CX3CR1 signalling pathway can reduce neuroinflammation by attenuating microglia activation in experimental diabetic retinopathy Journal of Cellular and Molecular Medicine, 2022-01-11;0(0):. 2022-01-11 [PMID: 35023309] (Western Blot, Rat)	Western Blot	Rat
ZH Wang, Y Xia, Z Wu, SS Kang, JC Zhang, P Liu, X Liu, W Song, V Huin, CM Dhaenens, SP Yu, XC Wang, K Ye Neuronal ApoE4 stimulates C/EBPbeta activation, promoting Alzheimer's disease pathology in a mouse model Progress in neurobiology, 2021-12-24;209(0):102212. 2021-12-24 [PMID: 34958873] (IHC, Rat)	IHC	Rat
Dragi? M, Mitrovi? N, Ad�i? M et al. Microglial- and Astrocyte-Specific Expression of Purinergic Signaling Components and Inflammatory Mediators in the Rat Hippocampus During Trimethyltin-Induced Neurodegeneration ASN Neuro 2021-09-27 [PMID: 34569324]
CA Finney, A Shvetcov, RF Westbrook, MJ Morris, NM Jones The selective estrogen receptor modulator tamoxifen protects against subtle cognitive decline and early markers of injury 24�h after hippocampal silent infarct in male Sprague-Dawley rats Hormones and behavior, 2021-07-06;134(0):105016. 2021-07-06 [PMID: 34242875] (IHC, Rat)	IHC	Rat
Dragi? M, Zeljkovi? M, Stevanovi? I et al. Downregulation of CD73/A(2A)R-Mediated Adenosine Signaling as a Potential Mechanism of Neuroprotective Effects of Theta-Burst Transcranial Magnetic Stimulation in Acute Experimental Autoimmune Encephalomyelitis Brain Sciences 2021-06-01 [PMID: 34205965]
María del Mar Fernández-Arjona, Ana León-Rodríguez, María Dolores López-Ávalos, Jesús M. Grondona Microglia activated by microbial neuraminidase contributes to ependymal cell death Fluids and Barriers of the CNS 2021-03-23 [PMID: 33757539]
Yang Liu, Huiqun Fu, Yan Wu, Binbin Nie, Fangyan Liu, Tianlong Wang et al. Elamipretide (SS-31) Improves Functional Connectivity in Hippocampus and Other Related Regions Following Prolonged Neuroinflammation Induced by Lipopolysaccharide in Aged Rats Frontiers in Aging Neuroscience 2021-03-01 [PMID: 33732135]
ZH Wang, Y Xia, P Liu, X Liu, L Edgington-, K Lei, SP Yu, XC Wang, K Ye ApoE4 activates C/EBP&beta/&delta-secretase with 27-hydroxycholesterol, driving the pathogenesis of Alzheimer's disease Progress in neurobiology, 2021-03-11;0(0):102032. 2021-03-11 [PMID: 33716161] (ICC, Neutralization, Western Blot, Rat)	ICC, Neutralization, Western Blot	Rat
Tomohiro Yamashita, Sawako Kamikaseda, Aya Tanaka, Hidetoshi Tozaki-Saitoh, Jose M. M. Caaveiro, Kazuhide Inoue et al. New Inhibitory Effects of Cilnidipine on Microglial P2X7 Receptors and IL-1 beta Release: An Involvement in its Alleviating Effect on Neuropathic Pain Cells 2021-02-18 [PMID: 33670748]
Z Chen, X Xie, N Jiang, J Li, L Shen, Y Zhang CCR5 signaling promotes lipopolysaccharide-induced macrophage recruitment and alveolar developmental arrest Cell Death & Disease, 2021-02-15;12(2):184. 2021-02-15 [PMID: 33589608] (IHC, Rat)	IHC	Rat
TB Rusbana, AZ Agista, WD Saputra, Y Ohsaki, K Watanabe, A Ardiansyah, S Budijanto, T Koseki, H Aso, M Komai, H Shirakawa Supplementation with Fermented Rice Bran Attenuates Muscle Atrophy in a Diabetic Rat Model Nutrients, 2020-08-12;12(8):. 2020-08-12 [PMID: 32806520] (Western Blot, Rat)	Western Blot	Rat
Matthew G. Frank, Michael V. Baratta, Kaixin Zhang, Isabella P. Fallon, Mikayleigh A. Pearson, Guozhen Liu et al. Acute stress induces the rapid and transient induction of caspase-1, gasdermin D and release of constitutive IL-1 beta protein in dorsal hippocampus Brain, Behavior, and Immunity 2020-11-01 [PMID: 32750541]
Amanda Ferreira Neves, Felipe Hertzing Farias, Silviane Fernandes de Magalhães, Dionéia Araldi, Marco Pagliusi, Claudia Herrera Tambeli et al. Peripheral Inflammatory Hyperalgesia Depends on P2X7 Receptors in Satellite Glial Cells Frontiers in Physiology 2020-05-25 [PMID: 32523543]
WS Lambert, S Pasini, JW Collyer, CR Formichell, P Ghose, BJ Carlson, DJ Calkins Of Mice and Monkeys: Neuroprotective Efficacy of the p38 Inhibitor BIRB 796 Depends on Model Duration in Experimental Glaucoma Sci Rep, 2020-05-22;10(1):8535. 2020-05-22 [PMID: 32444682] (IHC, Rat)	IHC	Rat
MDM Fernández-, JM Grondona, P Fernández-, MD López-Ával Microglial activation by microbial neuraminidase through TLR2 and TLR4 receptors J Neuroinflammation, 2019-12-02;16(1):245. 2019-12-02 [PMID: 31791382] (IHC, Mouse)	IHC	Mouse
María del Mar Fernández-Arjona, Jesús M. Grondona, Pedro Fernández-Llebrez, María D. López-Ávalos Microglial Morphometric Parameters Correlate With the Expression Level of IL-1 beta , and Allow Identifying Different Activated Morphotypes Frontiers in Cellular Neuroscience 2019-10-25 [PMID: 31708746]
M Yamamoto, M Kim, H Imai, Y Itakura, G Ohtsuki Microglia-Triggered Plasticity of Intrinsic Excitability Modulates Psychomotor Behaviors in Acute Cerebellar Inflammation Cell Rep, 2019-09-10;28(11):2923-2938.e8. 2019-09-10 [PMID: 31509752] (Western Blot, Rat)	Western Blot	Rat
ZH Wang, J Xiang, X Liu, SP Yu, FP Manfredsso, IM Sandoval, S Wu, JZ Wang, K Ye Deficiency in BDNF/TrkB Neurotrophic Activity Stimulates δ-Secretase by Upregulating C/EBP? in Alzheimer's Disease Cell Rep, 2019-07-16;28(3):655-669.e5. 2019-07-16 [PMID: 31315045] (Neutralization, Rat)	Neutralization	Rat
Inês Dinis Aires, Raquel Boia, Ana Catarina Rodrigues‐Neves, Maria Helena Madeira, Carla Marques, António Francisco Ambrósio et al. Blockade of microglial adenosine A 2A receptor suppresses elevated pressure‐induced inflammation, oxidative stress, and cell death in retinal cells Glia 2019-05-01 [PMID: 30667095]
HC Lai, CH Lu, CS Wong, BF Lin, SM Chan, CY Kuo, ZF Wu Baicalein attenuates neuropathic pain and improves sciatic nerve function recovery in rats with partial sciatic nerve transection J Chin Med Assoc, 2018-08-20;0(0):. 2018-08-20 [PMID: 30139671] (Rat)		Rat
CH Jo, S Kim, JS Park, GH Kim Anti-Inflammatory Action of Sitagliptin and Linagliptin in Doxorubicin Nephropathy Kidney Blood Press. Res., 2018-06-15;43(3):987-999. 2018-06-15 [PMID: 29913457] (ELISA Development (Capture), Rat)	ELISA Development (Capture)	Rat
P Zhang, RY Bi, YH Gan Glial interleukin-1? upregulates neuronal sodium channel 1.7 in trigeminal ganglion contributing to temporomandibular joint inflammatory hypernociception in rats J Neuroinflammation, 2018-04-20;15(1):117. 2018-04-20 [PMID: 29678208] (IHC, Western Blot, Rat)	IHC, Western Blot	Rat
Hannah Aucott, Johan Lundberg, Henna Salo, Lena Klevenvall, Peter Damberg, Lars Ottosson et al. Neuroinflammation in Response to Intracerebral Injections of Different HMGB1 Redox Isoforms Journal of Innate Immunity 2018-01-01 [PMID: 29478057]
L Taoro-Gonz, YM Arenas, A Cabrera-Pa, V Felipo Hyperammonemia alters membrane expression of GluA1 and GluA2 subunits of AMPA receptors in hippocampus by enhancing activation of the IL-1 receptor: underlying mechanisms J Neuroinflammation, 2018-02-08;15(1):36. 2018-02-08 [PMID: 29422059] (Western Blot, Rat)	Western Blot	Rat
HC Wang, HS Tsay, HN Shih, YA Chen, KM Chang, DC Agrawal, S Huang, YL Lin, MJ Lee Andrographolide relieved pathological pain generated by spared nerve injury model in mice Pharm Biol, 2018-12-01;56(1):124-131. 2018-12-01 [PMID: 29385888] (IHC, Mouse)	IHC	Mouse
CC Shih, HR Hwang, CI Chang, HM Su, PC Chen, HM Kuo, PJ Li, HD Wang, KH Tsui, YC Lin, SY Huang, ZH Wen Anti-Inflammatory and Antinociceptive Effects of Ethyl Acetate Fraction of an Edible Red Macroalgae Sarcodia ceylanica Int J Mol Sci, 2017-11-17;18(11):. 2017-11-17 [PMID: 29149031] (IHC, Rat)	IHC	Rat
R Natoli, N Fernando, M Madigan, JA Chu-Tan, K Valter, J Provis, M Rutar Microglia-derived IL-1? promotes chemokine expression by M�ller cells and RPE in focal retinal degeneration Mol Neurodegener, 2017-04-24;12(1):31. 2017-04-24 [PMID: 28438165] (Neutralization, Rat)	Neutralization	Rat
Congli Yuan Inhibition of phagocytosis and pyroptosis of macrophages promotes Bartonella invasion into the bloodstream through lymphatic circulation J. Infect. Dis., 2017-01-15;0(0):. 2017-01-15 [PMID: 27803173] (Western Blot, Rat)	Western Blot	Rat
Min Hui Kan, Ting Yang, Hui Qun Fu, Long Fan, Yan Wu, Niccolò Terrando et al. Pyrrolidine Dithiocarbamate Prevents Neuroinflammation and Cognitive Dysfunction after Endotoxemia in Rats Frontiers in Aging Neuroscience 2016-07-21 [PMID: 27493629]
V Hernandez-, A Cabrera-Pa, L Taoro-Gonz, A Gonzalez-U, A Agusti, T Balzano, M Llansola, V Felipo Neuroinflammation increases GABAergic tone and impairs cognitive and motor function in hyperammonemia by increasing GAT-3 membrane expression. Reversal by sulforaphane by promoting M2 polarization of microglia J Neuroinflammation, 2016-04-18;13(1):83. 2016-04-18 [PMID: 27090509] (Western Blot, Rat)	Western Blot	Rat
Jiao H, Natoli R, Valter K, Provis J, Rutar M Spatiotemporal Cadence of Macrophage Polarisation in a Model of Light-Induced Retinal Degeneration. PLoS ONE, 2015-12-02;10(12):e0143952. 2015-12-02 [PMID: 26630454] (IHC-Fr, Rat)	IHC-Fr	Rat
Jing Zhao, Yongshan Mou, Joshua D. Bernstock, Dace Klimanis, Sixian Wang, Maria Spatz et al. Synthetic Oligodeoxynucleotides Containing Multiple Telemeric TTAGGG Motifs Suppress Inflammasome Activity in Macrophages Subjected to Oxygen and Glucose Deprivation and Reduce Ischemic Brain Injury in Stroke-Prone Spontaneously Hypertensive Rats PLOS ONE 2015-10-16 [PMID: 26473731]
Madeira M, Elvas F, Boia R, Goncalves F, Cunha R, Ambrosio A, Santiago A Adenosine A2AR blockade prevents neuroinflammation-induced death of retinal ganglion cells caused by elevated pressure. J Neuroinflammation, 2015-06-10;12(0):115. 2015-06-10 [PMID: 26054642] (Neutralization, Rat)	Neutralization	Rat
Kathryn A. Jewett, Ping Taishi, Parijat Sengupta, Sandip Roy, Christopher J. Davis, James M. Krueger Tumor necrosis factor enhances the sleep-like state and electrical stimulation induces a wake-like state in co-cultures of neurons and glia European Journal of Neuroscience 2015-08-01 [PMID: 26036796]
Pablo Granados-Durán, María D. López-Ávalos, Jesús M. Grondona, María del Carmen Gómez-Roldán, Manuel Cifuentes, Margarita Pérez-Martín et al. Neuroinflammation Induced by Intracerebroventricular Injection of Microbial Neuraminidase Frontiers in Medicine 2015-03-17 [PMID: 25853134]
Silva G, Lopes P, Fonoff E, Pagano R The spinal anti-inflammatory mechanism of motor cortex stimulation: cause of success and refractoriness in neuropathic pain? J Neuroinflammation, 2015-01-20;12(0):10. 2015-01-20 [PMID: 25600429] (IHC, Rat)	IHC	Rat
Paniagua-Torija B, Arevalo-Martin A, Molina-Holgado E, Molina-Holgado F, Garcia-Ovejero D Spinal cord injury induces a long-lasting upregulation of interleukin-1beta in astrocytes around the central canal. Neuroscience, 2014-10-19;284(0):283-9. 2014-10-19 [PMID: 25453765] (IHC, Rat)	IHC	Rat
Fu H, Yang T, Xiao W, Fan L, Wu Y, Terrando N, Wang T Prolonged neuroinflammation after lipopolysaccharide exposure in aged rats. PLoS ONE, 2014-08-29;9(8):e106331. 2014-08-29 [PMID: 25170959] (IHC-Fr, Rat)	IHC-Fr	Rat
Ruozhou Tom Liu, Aikun Wang, Eleanor To, Jiangyuan Gao, Sijia Cao, Jing Z. Cui et al. Vinpocetine inhibits amyloid-beta induced activation of NF-kappa B, NLRP3 inflammasome and cytokine production in retinal pigment epithelial cells Experimental Eye Research 2014-10-01 [PMID: 25041941]
Shigemoto-Mogami Y, Hoshikawa K, Goldman J, Sekino Y, Sato K Microglia enhance neurogenesis and oligodendrogenesis in the early postnatal subventricular zone. J Neurosci, 2014-02-05;34(6):2231-43. 2014-02-05 [PMID: 24501362] (Neutralization, Rat)	Neutralization	Rat
Liu R, Gao J, Cao S, Sandhu N, Cui J, Chou C, Fang E, Matsubara J Inflammatory mediators induced by amyloid-beta in the retina and RPE in vivo: implications for inflammasome activation in age-related macular degeneration. Invest Ophthalmol Vis Sci, 2013-03-01;54(3):2225-37. 2013-03-01 [PMID: 23462752] (IHC-P, Rat)	IHC-P	Rat
Keratinocyte expression of inflammatory mediators plays a crucial role in substance P-induced acute and chronic pain. J Neuroinflammation, 2012-07-23;9(0):181. 2012-07-23 [PMID: 22824437] (IHC-Fr, Rat)	IHC-Fr	Rat
Faustino JV, Wang X, Johnson CE Microglial cells contribute to endogenous brain defenses after acute neonatal focal stroke. J. Neurosci., 2011-09-07;31(36):12992-3001. 2011-09-07 [PMID: 21900578] (IHC, Rat)	IHC	Rat
Barbara A. Cearley, James M. Blindheim, Barbara A. Churchill, Cassia N. Krueger, Kelly Churchill Acute Cocaine Increases Interleukin-1 beta mRNA and Immunoreactive Cells in the Cortex and Nucleus Accumbens Neurochemical Research 2011-04-01 [PMID: 21399909]
Sato K, Horiuchi Y, Jin Y, Malchinkhuu E, Komachi M, Kondo T, Okajima F Unmasking of LPA1 receptor-mediated migration response to lysophosphatidic acid by interleukin-1beta-induced attenuation of Rho signaling pathways in rat astrocytes. J. Neurochem., 2011-02-09;117(1):164-74. 2011-02-09 [PMID: 21244430] (Western Blot, Rat)	Western Blot	Rat
Qu WS, Wang YH, Ma JF, Tian DS, Zhang Q, Pan DJ, Yu ZY, Xie MJ, Wang JP, Wang W Galectin-1 attenuates astrogliosis-associated injuries and improves recovery of rats following focal cerebral ischemia. J. Neurochem., 2010-12-02;116(2):217-26. 2010-12-02 [PMID: 21054390] (IHC-Fr, Rat)	IHC-Fr	Rat
Summy-Long JY, Hu S Peripheral osmotic stimulation inhibits the brain's innate immune response to microdialysis of acidic perfusion fluid adjacent to supraoptic nucleus. Am. J. Physiol. Regul. Integr. Comp. Physiol., 2009-09-16;297(5):R1532-45. 2009-09-16 [PMID: 19759333] (IHC, Rat)	IHC	Rat
Lim G, Wang S, Zhang Y, Tian Y, Mao J Spinal leptin contributes to the pathogenesis of neuropathic pain in rodents. J. Clin. Invest., 2009-01-12;119(2):295-304. 2009-01-12 [PMID: 19139561] (Western Blot, Rat)	Western Blot	Rat
Russo TA, Beanan JM, Olson R, MacDonald U, Luke NR, Gill SR, Campagnari AA Rat pneumonia and soft-tissue infection models for the study of Acinetobacter baumannii biology. Infect. Immun., 2008-06-09;76(8):3577-86. 2008-06-09 [PMID: 18541654] (ELISA Development, Rat)	ELISA Development	Rat
Engstrom L, Rosen K, Angel A, Fyrberg A, Mackerlova L, Konsman JP, Engblom D, Blomqvist A Systemic immune challenge activates an intrinsically regulated local inflammatory circuit in the adrenal gland. Endocrinology, 2008-01-03;149(4):1436-50. 2008-01-03 [PMID: 18174279] (IHC-Fr, Rat)	IHC-Fr	Rat
Temporin K, Tanaka H, Kuroda Y, Okada K, Yachi K, Moritomo H, Murase T, Yoshikawa H IL-1beta promotes neurite outgrowth by deactivating RhoA via p38 MAPK pathway. Biochem. Biophys. Res. Commun., 2007-11-08;365(2):375-80. 2007-11-08 [PMID: 17996195] (ICC, Rat)	ICC	Rat
Colston JT, de la Rosa SD, Koehler M, Gonzales K, Mestril R, Freeman GL, Bailey SR, Chandrasekar B Wnt-induced secreted protein-1 is a prohypertrophic and profibrotic growth factor. Am. J. Physiol. Heart Circ. Physiol., 2007-07-06;293(3):H1839-46. 2007-07-06 [PMID: 17616748] (Neutralization, Rat)	Neutralization	Rat
Roche M, Diamond M, Finn DP In vivo modulation of LPS-induced alterations in brain and peripheral cytokines and HPA axis activity by cannabinoids. J. Neuroimmunol., 2006-09-29;181(1):57-67. 2006-09-29 [PMID: 17011047] (ELISA Development, Rat)	ELISA Development	Rat
Barkho BZ, Song H, Aimone JB Identification of astrocyte-expressed factors that modulate neural stem/progenitor cell differentiation. Stem Cells Dev., 2006-06-01;15(3):407-21. 2006-06-01 [PMID: 16846377] (Neutralization, Rat)	Neutralization	Rat
Assmus M, Svechnikov K, von Euler M, Setchell B, Sultana T, Zetterstrom C, Holst M, Soder O Single subcutaneous administration of chorionic gonadotropin to rats induces a rapid and transient increase in testicular expression of pro-inflammatory cytokines. Pediatr. Res., 2005-04-21;57(6):896-901. 2005-04-21 [PMID: 15845639] (IHC, Rat)	IHC	Rat
Park EM, Cho BP, Volpe BT, Cruz MO, Joh TH, Cho S Ibuprofen protects ischemia-induced neuronal injury via up-regulating interleukin-1 receptor antagonist expression. Neuroscience, 2005-01-01;132(3):625-31. 2005-01-01 [PMID: 15837124] (Western Blot, Rat)	Western Blot	Rat
Guo L, LaDu MJ, Van Eldik LJ A dual role for apolipoprotein e in neuroinflammation: anti- and pro-inflammatory activity. J. Mol. Neurosci., 2004-01-01;23(3):205-12. 2004-01-01 [PMID: 15181248] (Western Blot, Rat)	Western Blot	Rat
Nedrebo T, Reed RK, Jonsson R, Berg A, Wiig H Differential cytokine response in interstitial fluid in skin and serum during experimental inflammation in rats. J. Physiol. (Lond.), 2004-01-14;556(0):193-202. 2004-01-14 [PMID: 14724215] (IHC-Fr, Rat)	IHC-Fr	Rat
Nadeau S, Rivest S Glucocorticoids play a fundamental role in protecting the brain during innate immune response. J. Neurosci., 2003-07-02;23(13):5536-44. 2003-07-02 [PMID: 12843254] (Neutralization, Rat)	Neutralization	Rat
Show All 67 Publications. Collapse Publications.

Array AF-501-NA

• IL-1 beta/IL-1F2 Antibodies
• IL-1 beta/IL-1F2 ELISA Kits
• IL-1 beta/IL-1F2 Lysate
• IL-1 beta/IL-1F2 Proteins
• IL-1 beta/IL-1F2 ELISAs
• IL-1 beta/IL-1F2 Proteins and Enzymes