Home » IGSF2/CD101 » IGSF2/CD101 Antibodies » IGSF2/CD101 Antibody (307707) [Allophycocyanin]

IGSF2/CD101 Antibody (307707) [Allophycocyanin]

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Mouse GR-1 positive blood cells were stained with Rat Anti-Mouse IGSF2/CD101 APC-conjugated Monoclonal Antibody (Catalog # FAB3368A, filled histogram) or isotype control antibody (Catalog # IC006A, open histogram). View our protocol for Staining Membrane-associated Proteins.
Mouse GR-1 positive blood cells were stained with Rat Anti-Mouse IGSF2/CD101 APC-conjugated Monoclonal Antibody (Catalog # FAB3368A, filled histogram) or isotype control antibody (Catalog # IC006A, open histogram). View ...read more

Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow
Clone
307707
Clonality
Monoclonal
Host
Rat
Conjugate
Allophycocyanin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB3368U-100UG
Alexa Fluor 405
FAB3368V-100UG
Alexa Fluor 488
FAB3368G-100UG
Alexa Fluor 532
FAB3368X
Alexa Fluor 594
FAB3368T-100UG
Alexa Fluor 647
FAB3368R-100UG
Alexa Fluor 700
FAB3368N-100UG
Alexa Fluor 750
FAB3368S-100UG
Allophycocyanin/Cy7
FAB3368APCCY7
Biotin
BAM3368
CoraFluor 1
FAB3368CL1
DyLight 350
FAB3368D
DyLight 405
FAB3368E
DyLight 488
FAB3368K
DyLight 550
FAB3368L
DyLight 594
FAB3368M
DyLight 650
FAB3368W
DyLight 680
FAB3368Y
DyLight 755
FAB3368Z
HRP
FAB3368H
Janelia Fluor 525
FAB3368JF525
Janelia Fluor 549
FAB3368I
Janelia Fluor 646
FAB3368J
Janelia Fluor 669
FAB3368JF669
PE/Atto594
FAB3368PEATT594
PE/Cy5.5
FAB3368PECY55
PE/Cy7
FAB3368PECY7
PerCP
FAB3368C
Unconjugated
MAB3368
mFluor Violet 450 SE
FAB3368MFV450
mFluor Violet 500 SE
FAB3368MFV500
mFluor Violet 610 SE
FAB3368MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB3368
Carrier Free
MAB3368
Carrier Free
MAB3368-SP
Carrier Free
FAB3368V-100UG
Carrier Free
FAB3368U-100UG
Carrier Free
FAB3368T-100UG
Carrier Free
FAB3368S-100UG
Carrier Free
FAB3368R-100UG
Carrier Free
FAB3368N-100UG
Carrier Free
FAB3368G-100UG
Novus Biologicals offers 100% Guarantee

IGSF2/CD101 Antibody (307707) [Allophycocyanin] Summary

Immunogen
Chinese hamster ovary cell line CHO-derived recombinant mouse IGSF2/CD101
Gln21-Tyr1033
Accession # A8E0Y8
Specificity
Detects mouse IGSF2/CD101 in flow cytometry.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
CD101
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for IGSF2/CD101 Antibody (307707) [Allophycocyanin]

  • CD101 antigen
  • CD101 molecule
  • CD101
  • Cell surface glycoprotein V7
  • EWI101
  • EWI-101
  • Glu-Trp-Ile EWI motif-containing protein 101
  • IGSF2
  • Leukocyte Surface Protein
  • member 2
  • V7

Background

IGSF2, also known as CD101 and V7 is a 135-140 kDa member of the EWI family, Ig superfamily of molecules. It is a type I transmembrane glycoprotein that is expressed on dermal dendritic cells (DCs), granulocytes, monocytes, activated T cells, and Tregs. IGSF2 ligation is involved in T cell activation. On dermal DCs, CD101 ligation induces IL-10 expression, and on activated T cells, CD101 ligation blocks IL-2 expression, two effects that downregulate T cell activity. Notably, in mouse, CD101 expression on CD62L++ Tregs identifies a population of cells that have potent suppressor activity. The extracellular domain of mouse shares 86% and 69% amino acid sequence identity with the ECD of rat and human CD101, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CD101
Uniprot