Human Total Bax-alpha DuoSet IC ELISA, 2 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

B cell leukemia/lymphoma-2 associated X protein (Bax) is a pro-apoptotic member of the Bcl-2 family of proteins found in many cell types. Bax is a cytosolic protein that translocates to the mitochondria and participates in Cytochrome c release in response to apoptotic stimuli. Aberrant expression of Bcl-2 family members can inappropriately promote or prevent apoptosis. Increased expression of Bax is associated with the apoptotic loss of neurons in Parkinson's disease.

We have publications tested in 3 confirmed species: Human, Mouse, Rat.

Showing Publications 1 - 9 of 9.

Publications using DYC820-2	Applications	Species
MA Almayouf, MF El-Khadrag, MA Awad, EM Al-Olayan The Effects of Silver Nanoparticles Biosynthesized Using Fig and Olive Extracts on Cutaneous leishmaniasis Induced Inflammation in Female Balb/c Mice Bioscience Reports, 2020-11-30;0(0):. 2020-11-30 [PMID: 33252120] (Mouse)		Mouse
HQ Li, JJ Fan, XH Li, D Bao MiR-507 inhibits the growth and invasion of trophoblasts by targeting CAMK4 Eur Rev Med Pharmacol Sci, 2020-06-01;24(11):5856-5862. 2020-06-01 [PMID: 32572897] (Human)		Human
RJ Playford, T Marchbank Pancreatic secretory trypsin inhibitor reduces multi-organ injury caused by gut ischemia/reperfusion in mice PLoS ONE, 2020-01-10;15(1):e0227059. 2020-01-10 [PMID: 31923181] (Human)		Human
MF El-Khadrag, EM Al-Olayan, MIY Elmallah, AM Alharbi, HM Yehia, AE Abdel Mone Probiotics and yogurt modulate oxidative stress and fibrosis in livers of Schistosoma mansoni-infected mice BMC Complement Altern Med, 2019-01-03;19(1):3. 2019-01-03 [PMID: 30606163] (Mouse)		Mouse
F He, CC Chuang, T Zhou, Q Jiang, DA Sedlock, L Zuo Redox correlation in muscle lengthening and immune response in eccentric exercise PLoS ONE, 2018-12-27;13(12):e0208799. 2018-12-27 [PMID: 30589838] (Human)		Human
Abdullah A, Mohammed A, Rasedee A, Mirghani M Oxidative stress-mediated apoptosis induced by ethanolic mango seed extract in cultured estrogen receptor positive breast cancer MCF-7 cells. Int J Mol Sci, 2015-02-05;16(2):3528-36. 2015-02-05 [PMID: 25664859] (Human)		Human
Poggi A, Prevosto C, Catellani S, Rocco I, Garuti A, Zocchi MR Engagement of CD31 delivers an activating signal that contributes to the survival of chronic lymphocytic leukaemia cells. Br. J. Haematol., 2010-08-31;151(3):252-64. 2010-08-31 [PMID: 20813004] (Human)		Human
Grcevic D, Kusec R, Kovacic N, Lukic A, Lukic IK, Ivcevic S, Nemet D, Seiwerth RS, Ostojic SK, Croucher PI, Marusic A Bone morphogenetic proteins and receptors are over-expressed in bone-marrow cells of multiple myeloma patients and support myeloma cells by inducing ID genes. Leuk. Res., 2009-11-18;34(6):742-51. 2009-11-18 [PMID: 19926132] (Human)		Human
Vucicevic L, Misirkic M, Janjetovic K, Harhaji-Trajkovic L, Prica M, Stevanovic D, Isenovic E, Sudar E, Sumarac-Dumanovic M, Micic D, Trajkovic V AMP-activated protein kinase-dependent and -independent mechanisms underlying in vitro antiglioma action of compound C. Biochem. Pharmacol., 2009-03-14;77(11):1684-93. 2009-03-14 [PMID: 19428322] (Human, Mouse, Rat)		Human, Mouse, Rat

Array DYC820-2

• Bax-alpha ELISA