I need to know about TNF-alpha antibody kits for mice.

We currently have two TNFalpha ELISA kits specific for mouse: catalog numbers KA0257 and NBP1-92670.

I would like to ask you for help. I need an antibody for Elisa to detect human TNF alpha in a supernatant from a cell culture (meaning supernatant after centrifugation of collected cell suspension from a plate well). Which of your antibodies against human tnf alpha would be suitable? I would like to buy only the primary antibody.

I would recommend catalog number NBP1-67821 or NB600-587; however, a full list of our anti-human TNF alpha antibodies suitable for use in ELISA can be found using this link.

I am interested in a TNF alpha antibody, cross reactive for human, rat and mouse (host species: rabbit). Could your product NBP1-19532 be used in western blotting applications? Or do you have a similar product in your catalog which could fit with my request?

The antibody you mention, NBP1-19532, has not yet been validated in Western blot. I would instead recommend either NBP1-67821 or NB600-587. These are both rabbit polyclonal antibodies that cross-reacts with human, mouse and rat and have been used in Western blotting.

Can your TNF-alpha products be used to treat TBI victims and therefore avoid the perispinal injections with Enbrel?

I am very sorry, but all of our products are for scientific research use only, and none are intended or approved for use in humans.

Novus Biologicals products are now on bio-techne.com

Human TNF-alpha Quantikine HS ELISA

Name: Human TNF-alpha Quantikine HS ELISA
Brand: Novus Biologicals
SKU: HSTA00E
Price: 675 USD

(255 Publications)

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Product Details

Summary

Reactivity	HuSpecies Glossary
Applications	ELISA
Conjugate	HRP

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Catalog# & Conjugate	Size	Price
HRP SSTA00E

HRP PHSTA00E

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Catalog# & Formulation	Size	Price
Carrier Free SSTA00E

Carrier Free PHSTA00E

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Conjugate	Catalog #	Availability	Size	Price
HRP	SSTA00E
HRP	PHSTA00E

Human TNF-alpha Quantikine HS ELISA Summary

Background	The Quantikine® HS Human TNF-alpha Immunoassay is a 4.0 hour solid phase ELISA designed to measure human TNF-alpha in serum and plasma. It contains E. coli-derived recombinant human TNF-alpha and antibodies raised against the recombinant factor. It has been shown to accurately quantitate recombinant human TNF-alpha . Results obtained with natural human TNF-alpha samples showed linear cu...rves that were parallel to the standard curves obtained using the Quantikine® kit standards. These results indicate that this kit can be used to determine relative mass values for natural human TNF-alpha . Show More
Specificity	Natural and recombinant human TNF-alpha .
Source	N/A
Inter-Assay	See PDF Datasheet for details
Intra-Assay	See PDF Datasheet for details
Spike Recovery	See PDF Datasheet for details
Sample Volume	See PDF Datasheet for details

Applications/Dilutions

Dilutions

ELISA

Application Notes

No significant interference observed with available related molecules.

Publications

Read Publications using
HSTA00E in the following applications:

ELISA
1 publication

Packaging, Storage & Formulations

Storage

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human TNF-alpha Quantikine HS ELISA

APC1 protein
Cachectin
Cachetin
DIF
TNF
TNF, monocyte-derived
TNFA
TNF-A
TNFalpha
TNF-alpha
TNF-alphacachectin
TNFATNF, macrophage-derived
TNFG1F
TNFSF1A
TNFSF2
TNFSF2TNF superfamily, member 2
tumor necrosis factor (TNF superfamily, member 2)
tumor necrosis factor alpha
Tumor necrosis factor ligand superfamily member 2
tumor necrosis factor
tumor necrosis factor-alpha

Background

Tumor Necrosis Factor alpha (TNF-alpha ), also known as cachectin and TNFSF1A, is the prototypic ligand of the TNF superfamily (1). It is a pleiotropic molecule that plays a central role in inflammation, immune system development, apoptosis, and lipid metabolism (2-5). TNF-alpha is also involved in a number of pathological conditions including asthma, Crohn's disease, rheumatoid arthritis, neuropathic pain, obesity, type 2 diabetes, septic shock, autoimmunity, and cancer (5-11).

Human TNF-alpha is synthesized as a 26 kDa type II transmembrane protein that consists of a 35 amino acid (aa) cytoplasmic domain, a 21 aa transmembrane segment, and a 177 aa extracellular domain (ECD) (12, 13). Within the ECD, human TNF-alpha shares 97% aa sequence identity with rhesus monkey, and 71%-92% aa identity with bovine, canine, cotton rat, equine, feline, mouse, porcine, and rat TNF-alpha . It is produced by a wide variety of immune, epithelial, endothelial, and tumor cells. TNF-alpha is assembled intracellularly to form a noncovalently linked homotrimer which is expressed on the cell surface (14). Cell surface TNF-alpha can both induce the lysis of tumor cells and virus infected cells, and generate its own downstream cell signaling following ligation by soluble TNF RI (15, 16). Shedding of membrane bound TNF-alpha by TACE/ ADAM17 releases the bioactive cytokine, a 55 kDa soluble trimer of the TNF-alpha extracellular domain (17-19).

TNF-alpha binds the ubiquitous 55-60 kDa TNF RI (20, 21) and the hematopoietic cell-restricted 78-80 kDa TNF RII (22, 23), both of which are also expressed as homotrimers (1, 24). Both type I and type II receptors bind TNF-alpha with comparable affinity and can promote NF kappa B activation (25-28). Only TNF RI, however, contains a cytoplasmic death domain which triggers the activation of apoptosis (3, 29). Soluble forms of both types of receptors are released into human serum and urine and can neutralize the biological activity of TNF-alpha (30-32).

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Human TNF-alpha
Quantikine HS ELISA

HSTA00E

Species: Hu

Applications: ELISA

⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for TNF-alpha (HSTA00E)(255)

We have publications tested in 2 confirmed species: Human, Rat.

We have publications tested in 1 application: ELISA.

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ELISA

(1)

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Human

(253)

Rat

(1)

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Showing Publications 1 - 10 of 255. Show All 255 Publications.

Publications using HSTA00E	Applications	Species
Koutaki, D;Paltoglou, G;Manou, M;Vourdoumpa, A;Ramouzi, E;Tzounakou, AM;Michos, A;Bacopoulou, F;Mantzou, E;Zoumakis, E;Papadopoulou, M;Kassari, P;Charmandari, E; The Role of Secreted Frizzled-Related Protein 5 (Sfrp5) in Overweight and Obesity in Childhood and Adolescence Nutrients 2024-09-17 [PMID: 39339733] (Human)		Human
Marino, M;Del Bo', C;Martini, D;Perna, S;Porrini, M;Cherubini, A;Gargari, G;Meroño, T;Hidalgo-Liberona, N;Andres-Lacueva, C;Kroon, PA;Guglielmetti, S;Riso, P; A (poly)phenol-rich diet reduces serum and faecal calprotectin in older adults with increased intestinal permeability: the MaPLE randomised controlled trial BMC geriatrics 2024-08-24 [PMID: 39182041] (Human)		Human
Hirano, M;Iwata, K;Yamada, Y;Shinoda, Y;Yamazaki, M;Hino, S;Ikeda, A;Shimizu, A;Otsuka, S;Nakagawa, H;Watanabe, Y; AlveoMPU: Bridging the Gap in Lung Model Interactions Using a Novel Alveolar Bilayer Film Polymers 2024-05-23 [PMID: 38891433] (Human)		Human
Onodera, T;Iwasaki, K;Matsuoka, M;Morioka, Y;Matsubara, S;Kondo, E;Iwasaki, N; The alterations in nerve growth factor concentration in plasma and synovial fluid before and after total knee arthroplasty Scientific reports 2024-04-18 [PMID: 38637604] (ELISA, Human)	ELISA	Human
Neubauer-Geryk, J;Wielicka, M;My?liwiec, M;Zorena, K;Bieniaszewski, L; The Impact of Metabolic Memory on Immune Profile in Young Patients with Uncomplicated Type 1 Diabetes International journal of molecular sciences 2024-03-10 [PMID: 38542165] (Human)		Human
Roberts, MJ;Hamrouni, M;Wadley, AJ;Bishop, NC; Adipose inflammation: South Asian ethnicity and central obesity are independently associated with higher immune cell recruitment to adipose-specific media: A pilot study in men Physiological reports 2023-11-01 [PMID: 38011590] (Human)		Human
Son, WH;Park, HT;Jeon, BH;Ha, MS; Moderate intensity walking exercises reduce the body mass index and vascular inflammatory factors in postmenopausal women with obesity: a randomized controlled trial Scientific reports 2023-11-17 [PMID: 37978254] (Human)		Human
Mrakic-Sposta, S;Vezzoli, A;Garetto, G;Paganini, M;Camporesi, E;Giacon, TA;Dellanoce, C;Agrimi, J;Bosco, G; Hyperbaric Oxygen Therapy Counters Oxidative Stress/Inflammation-Driven Symptoms in Long COVID-19 Patients: Preliminary Outcomes Metabolites 2023-09-25 [PMID: 37887357] (Human)		Human
Donate-Correa, J;Martín-Núñez, E;Mora-Fernández, C;González-Luis, A;Martín-Olivera, A;Navarro-González, JF; Associations between Inflammation, Hemoglobin Levels, and Coronary Artery Disease in Non-Albuminuric Subjects with and without Type 2 Diabetes Mellitus International journal of molecular sciences 2023-09-15 [PMID: 37762433] (Human)		Human
Corley, E;Patlola, SR;Laighneach, A;Corvin, A;McManus, R;Kenyon, M;Kelly, JP;Mckernan, DP;King, S;Hallahan, B;Mcdonald, C;Morris, DW;Donohoe, G; Genetic and inflammatory effects on childhood trauma and cognitive functioning in patients with schizophrenia and healthy participants Brain, behavior, and immunity 2023-09-23 [PMID: 37748567] (Human)		Human
Niemelä, O;Bloigu, A;Bloigu, R;Nivukoski, U;Kultti, J;Pohjasniemi, H; Patterns of IgA Autoantibody Generation, Inflammatory Responses and Extracellular Matrix Metabolism in Patients with Alcohol Use Disorder International journal of molecular sciences 2023-08-23 [PMID: 37685930] (Human)		Human
Li, H;Zhao, M;Jiang, C;Zhao, H;Wu, C;Li, Y;Zhang, S;Xu, P;Mou, T;Xu, Y;Huang, M; Elevated Plasma Levels of Mature Brain-Derived Neurotrophic Factor in Major Depressive Disorder Patients with Higher Suicidal Ideation Brain sciences 2023-08-21 [PMID: 37626579] (Human)		Human
Barone, JC;Wenzel, E;Alluri, V;Moriarity, D;Pinna, G;Walsh, E;Rubinow, DR;Morrow, AL;Eisenlohr-Moul, TA; Effects of estrogen and progesterone on neuroactive steroids and cytokines in patients with suicidality Psychoneuroendocrinology 2023-08-09 [PMID: 37611527] (Human)		Human
Lopes, KG;de Souza, MDGC;Bouskela, E;Kraemer-Aguiar, LG; Microvascular Function, Inflammatory Status, and Oxidative Stress in Post-Bariatric Patients with Weight Regain Nutrients 2023-04-29 [PMID: 37432255] (Human)		Human
Detopoulou, P;Damigou, E;Antonopoulou, S;Fragopoulou, E;Chysohoou, C;Pitsavos, C;Panagiotakos, D; Food Compass Score and its association with inflammatory markers and homocysteine in cardiovascular disease-free adults: a cross-sectional analysis of the ATTICA epidemiological study European journal of clinical nutrition 2023-07-03 [PMID: 37400562] (Human)		Human
Caldú, X;Prats-Soteras, X;García-García, I;Prunell-Castañé, A;Sánchez-Garre, C;Cano, N;Tor, E;Sender-Palacios, MJ;Ottino-González, J;Garolera, M;Jurado, MÁ; Body mass index, systemic inflammation and cognitive performance in adolescents: A cross-sectional study Psychoneuroendocrinology 2023-05-23 [PMID: 37295218]
Zhu, X;Zhang, Q;Du, X;Jiang, Y;Niu, Y;Wei, Y;Zhang, Y;Chillrud, SN;Liang, D;Li, H;Chen, R;Kan, H;Cai, J; Respiratory Effects of Traffic-Related Air Pollution: A Randomized, Crossover Analysis of Lung Function, Airway Metabolome, and Biomarkers of Airway Injury Environmental health perspectives 2023-05-01 [PMID: 37141245] (Human)		Human
Verschoor, CP;Vlasschaert, C;Rauh, MJ;Par�, G; A DNA methylation based measure outperforms circulating CRP as a marker of chronic inflammation and partly reflects the monocytic response to long-term inflammatory exposure: A�Canadian longitudinal study of aging analysis Aging cell 2023-05-04 [PMID: 37139638] (Human)		Human
R De Marco, AW Barritt, M Cercignani, G Cabbai, A Colasanti, NA Harrison Inflammation-induced reorientation of reward versus punishment sensitivity is attenuated by Minocycline Brain, Behavior, and Immunity, 2023-04-25;0(0):. 2023-04-25 [PMID: 37105388] (Human)		Human
RG Reed, SR Presnell, A Al-Attar, CT Lutz, SC Segerstrom Life stressors and immune aging: Protective effects of cognitive reappraisal Brain, Behavior, and Immunity, 2023-03-08;110(0):212-221. 2023-03-08 [PMID: 36893924] (Human)		Human
RG Reed, SR Presnell, A Al-Attar, CT Lutz, SC Segerstrom Life stressors and immune aging: Protective effects of cognitive reappraisal Brain, Behavior, and Immunity, 2023;110(0):212-221. 2023 [PMID: 36893924] (Human)		Human
E Hochman, M Taler, R Flug, S Gur, S Dar, G Bormant, D Blattberg, U Nitzan, A Krivoy, A Weizman Serum claudin-5 levels among patients with unipolar and bipolar depression in relation to the pro-inflammatory cytokine tumor necrosis factor-alpha levels Brain, Behavior, and Immunity, 2023-01-24;109(0):162-167. 2023-01-24 [PMID: 36706845] (Human)		Human
J Ferreira, M Oliveira, M Bicho, F Serejo Role of Inflammatory/Immune Response and Cytokine Polymorphisms in the Severity of Chronic Hepatitis C (CHC) before and after Direct Acting Antiviral (DAAs) Treatment International Journal of Molecular Sciences, 2023-01-10;24(2):. 2023-01-10 [PMID: 36674897] (Human)		Human
K Wolk, D Wilsmann-T, K Witte, TC Brembach, C Kromer, S Gerdes, K Ghoreschi, K Reich, R Mössner, R Sabat Interleukin-19 Levels Are Increased in Palmoplantar Pustulosis and Reduced following Apremilast Treatment International Journal of Molecular Sciences, 2023-01-09;24(2):. 2023-01-09 [PMID: 36674793] (Human)		Human
H Karpin, JJ Vatine, Y Bachar Kir, A Markezana, I Weissman-F Central Sensitization and Psychological State Distinguishing Complex Regional Pain Syndrome from Other Chronic Limb Pain Conditions: A Cluster Analysis Model Biomedicines, 2022-12-29;11(1):. 2022-12-29 [PMID: 36672597] (Human)		Human
M Kouvari, E Damigou, M Florentin, RI Kosti, C Chrysohoou, CS Pitsavos, DB Panagiotak Egg Consumption, Cardiovascular Disease and Cardiometabolic Risk Factors: The Interaction with Saturated Fatty Acids. Results from the ATTICA Cohort Study (2002-2012) Nutrients, 2022-12-12;14(24):. 2022-12-12 [PMID: 36558450] (Human)		Human
WJ Lin, WJ Lee, LN Peng, YL Huang, CY Tung, CH Lin, TF Tsai, LK Chen Anti-tumor necrosis factor-alpha is potentially better than tumor necrosis factor-alpha as the biomarker for sarcopenia: Results from the I-Lan longitudinal aging study Experimental gerontology, 2022-12-09;172(0):112053. 2022-12-09 [PMID: 36509297] (Human)		Human
Y Song, HC Paik, N Kim, H Jung, JG Lee, YC Yoo Effect of Propofol versus Sevoflurane Anesthesia on Acute Kidney Injury after Lung Transplantation Surgery: A Prospective Randomized Controlled Trial Journal of Clinical Medicine, 2022-11-21;11(22):. 2022-11-21 [PMID: 36431341] (Human)		Human
L Juhász, H L?rincz, A Szentpéter, B Nádró, É Varga, G Paragh, M Harangi Sphingosine 1-Phosphate and Apolipoprotein M Levels and Their Correlations with Inflammatory Biomarkers in Patients with Untreated Familial Hypercholesterolemia International Journal of Molecular Sciences, 2022-11-15;23(22):. 2022-11-15 [PMID: 36430543] (Human)		Human
L Stiefvatte, K Frick, K Lehnert, W Vetter, A Montoya-Ar, J Frank, U Schmid-Sta, SC Bischoff Potentially Beneficial Effects on Healthy Aging by Supplementation of the EPA-Rich Microalgae Phaeodactylum tricornutum or Its Supernatant-A Randomized Controlled Pilot Trial in Elderly Individuals Marine Drugs, 2022-11-15;20(11):. 2022-11-15 [PMID: 36421994] (Human)		Human
M Górecka, K Krzemi?ski, T Mikulski, AW Ziemba ANGPTL4, IL-6 and TNF-alpha as regulators of lipid metabolism during a marathon run Scientific Reports, 2022-11-19;12(1):19940. 2022-11-19 [PMID: 36402848] (Human)		Human
S Lee, M Han, S Kim, R Cha, S Kang, J Kim, W An Indoxyl Sulfate Might Play a Role in Sarcopenia, While Myostatin Is an Indicator of Muscle Mass in Patients with Chronic Kidney Disease: Analysis from the RECOVERY Study Toxins, 2022-09-23;0(0):. 2022-09-23 [PMID: 36287929] (Human)		Human
RM Critelli, F Milosa, A Romanzi, S Lasagni, G Marcelli, L Di Marco, A Pivetti, F Schepis, D Romagnoli, S Mancarella, F Dituri, ML Martinez-C, G Giannelli, E Villa Upregulation of the oestrogen target gene SIX1 is associated with higher growth speed and decreased survival in HCV-positive women with hepatocellular carcinoma Oncology Letters, 2022-09-21;24(5):395. 2022-09-21 [PMID: 36276500] (Human)		Human
S Ugovšek, A Rehberger, S Finderle, G Poglajen, R Okrajšek, B Vrtovec, M Šebeštjen TNF-alpha Predicts Endothelial Function and Number of CD34+ Cells after Stimulation with G-CSF in Patients with Advanced Heart Failure Journal of cardiovascular development and disease, 2022-08-20;9(8):. 2022-08-20 [PMID: 36005445] (Human)		Human
MS Simon, BB Barton, C Glocker, R Musil A comprehensive approach to predicting weight gain and therapy response in psychopharmacologically treated major depressed patients: A cohort study protocol PLoS ONE, 2022-07-21;17(7):e0271793. 2022-07-21 [PMID: 35862413] (Human)		Human
RJ Pawlik, L Petrakova, L Brotte, H Engler, S Benson, S Elsenbruch Circulating Pro-inflammatory Cytokines Do Not Explain Interindividual Variability in Visceral Sensitivity in Healthy Individuals Frontiers in Neuroscience, 2022-07-04;16(0):876490. 2022-07-04 [PMID: 35860299] (Human)		Human
C Masama, DA Jarkas, E Thaw, AZB Daneshmend, SI Franklyn, C Beaurepair, RJ McQuaid Hormone contraceptive use in young women: Altered mood states, neuroendocrine and inflammatory biomarkers Hormones and behavior, 2022-06-29;144(0):105229. 2022-06-29 [PMID: 35779518] (Human)		Human
P Binou, AE Yanni, K Kartsioti, A Barmpagian, P Konstantop, VT Karathanos, A Kokkinos Wheat Biscuits Enriched with Plant-Based Protein Contribute to Weight Loss and Beneficial Metabolic Effects in Subjects with Overweight/Obesity Nutrients, 2022-06-17;14(12):. 2022-06-17 [PMID: 35745249] (Human)		Human
S Ekstedt, K Piersiala, M Petro, A Karlsson, Å Kågedal, S Kumlien Ge, LO Cardell A prolonged innate systemic immune response in COVID-19 Oncogene, 2022-06-15;12(1):9915. 2022-06-15 [PMID: 35705573] (Human)		Human
JM Kim, HJ Kang, JW Kim, M Jhon, W Choi, JY Lee, SW Kim, IS Shin, MG Kim, R Stewart Prospective associations of multimodal serum biomarkers with 12-week and 12-month remission in patients with depressive disorders receiving stepwise psychopharmacotherapy Brain, Behavior, and Immunity, 2022-05-23;104(0):65-73. 2022-05-23 [PMID: 35618226] (Human)		Human
E Martín-Núñ, A Pérez-Cast, VG Tagua, C Hernández-, C Ferri, N Pérez-Delg, S Rodríguez-, P Cerro-Lópe, Á López-Cast, A Delgado-Mo, VC López-Tarr, MA Arévalo-Gó, A González-L, A Martín-Oli, CC Morales-Es, C Mora-Ferná, J Donate-Cor, JF Navarro-Go Klotho expression in peripheral blood circulating cells is associated with vascular and systemic inflammation in atherosclerotic vascular disease Scientific Reports, 2022-05-19;12(1):8422. 2022-05-19 [PMID: 35590090] (Human)		Human
N Kurgan, H Islam, JBL Matusiak, BJ Baranowski, J Stoikos, VA Fajardo, REK MacPherson, BJ Gurd, P Klentrou Subcutaneous adipose tissue sclerostin is reduced and Wnt signaling is enhanced following 4-weeks of sprint interval training in young men with obesity Physiological Reports, 2022-03-01;10(6):e15232. 2022-03-01 [PMID: 35312183] (Human)		Human
K Kitamura, H Shionoya, S Suzuki, R Fukai, S Uda, C Abe, H Takemori, K Nishimura, H Baba, K Katayama, K Terato, T Waritani Oral and Intestinal Bacterial Substances Associated with Disease Activities in Patients with Rheumatoid Arthritis: A Cross-Sectional Clinical Study Journal of Immunology Research, 2022-02-18;2022(0):6839356. 2022-02-18 [PMID: 35224112] (Human)		Human
C Bao, J Lv, JR Chen, GZ Wei, N Liu, YT Wang, Z Ding, WB Liu, XD Li, HJ Cao, J Sheng, KY Liu, J He, FB Tao, QN Wang Chronic inflammation as a potential mediator between phthalate exposure and depressive symptoms Ecotoxicology and environmental safety, 2022-02-16;233(0):113313. 2022-02-16 [PMID: 35182801] (Human)		Human
YC Liu, HT Hsiao, JC Wang, TC Wen, SL Chen TGF-beta1 in plasma and cerebrospinal fluid can be used as a biological indicator of chronic pain in patients with osteoarthritis PLoS ONE, 2022-01-21;17(1):e0262074. 2022-01-21 [PMID: 35061744] (Human)		Human
RS Perera, L Chen, DJ Hart, TD Spector, NK Arden, ML Ferreira, MR Radoj?i? Effects of body weight and fat mass on back pain - direct mechanical or indirect through inflammatory and metabolic parameters? Seminars in arthritis and rheumatism, 2021-12-30;0(0):151935. 2021-12-30 [PMID: 35027244] (Human)		Human
AK Dubey, J Sahoo, B Vairappan, S Parameswar, P Ps Prevalence and determinants of sarcopenia in Indian patients with chronic kidney disease stage 3 & 4 Osteoporosis and sarcopenia, 2021-12-04;7(4):153-158. 2021-12-04 [PMID: 35005252] (Human)		Human
C Gar, B Thorand, C Herder, C Sujana, M Heier, C Meisinger, A Peters, W Koenig, W Rathmann, M Roden, M Stumvoll, H Maalmi, T Meitinger, H Then, J Seissler, C Then Association of circulating MR-proADM with all-cause and cardiovascular mortality in the general population: Results from the KORA F4 cohort study PLoS ONE, 2022-01-06;17(1):e0262330. 2022-01-06 [PMID: 34990470] (Human)		Human
C Griffen, M Duncan, J Hattersley, MO Weickert, A Dallaway, D Renshaw Effects of resistance exercise and whey protein supplementation on skeletal muscle strength, mass, physical function, and hormonal and inflammatory biomarkers in healthy active older men: A randomised, double-blind, placebo-controlled trial Experimental gerontology, 2021-12-09;0(0):111651. 2021-12-09 [PMID: 34896568] (Human)		Human
H Matsumoto, Y Fujita, T Asano, N Matsuoka, J Temmoku, S Sato, M Yashiro-Fu, K Yokose, S Yoshida, E Suzuki, T Yago, H Watanabe, A Kawakami, K Migita Association between inflammatory cytokines and immune-checkpoint molecule in rheumatoid arthritis PLoS ONE, 2021-11-18;16(11):e0260254. 2021-11-18 [PMID: 34793561] (Human)		Human
J Leppänen, K Randell, U Schwab, J Pihlajamäk, J Romppanen, L Keski-Nisu, S Heinonen, T Laitinen Endothelial function and concentrations of high-sensitivity C-reactive protein, interleukin-6, and tumor necrosis factor-alpha during a long agonist IVF protocol Journal of reproductive immunology, 2021-10-19;148(0):103434. 2021-10-19 [PMID: 34688101] (Human)		Human
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Venkateswaran RV, Dronavalli V, Lambert PA, Steeds RP, Wilson IC, Thompson RD, Mascaro JG, Bonser RS The proinflammatory environment in potential heart and lung donors: prevalence and impact of donor management and hormonal therapy. Transplantation, 2009-08-27;88(4):582-8. 2009-08-27 [PMID: 19696643] (Human)		Human
Jaiyen Y, Masrinoul P, Kalayanarooj S, Pulmanausahakul R, Ubol S Characteristics of dengue virus-infected peripheral blood mononuclear cell death that correlates with the severity of illness. Microbiol. Immunol., 2009-08-01;53(8):442-50. 2009-08-01 [PMID: 19659928] (Human)		Human
Sun Y, Yi D, Wang Y, Zheng R, Sun G, Wang J, Liu Y, Ren J, Wang Y, Zhang S, Gu C, Pei J Age-dependent mobilization of circulating endothelial progenitor cells in infants and young children undergoing cardiac surgery with cardiopulmonary bypass. Cytokine, 2009-07-24;47(3):206-13. 2009-07-24 [PMID: 19632131] (Human)		Human
Welsh P, Woodward M, Rumley A, Lowe G Associations of circulating TNFalpha and IL-18 with myocardial infarction and cardiovascular risk markers: the Glasgow Myocardial Infarction Study. Cytokine, 2009-07-05;47(2):143-7. 2009-07-05 [PMID: 19581111] (Human)		Human
Livshits G, Zhai G, Hart DJ, Kato BS, Wang H, Williams FM, Spector TD Interleukin-6 is a significant predictor of radiographic knee osteoarthritis: The Chingford Study. Arthritis Rheum., 2009-07-01;60(7):2037-45. 2009-07-01 [PMID: 19565477] (Human)		Human
Yaffe K, Fiocco AJ, Lindquist K, Vittinghoff E, Simonsick EM, Newman AB, Satterfield S, Rosano C, Rubin SM, Ayonayon HN, Harris TB Predictors of maintaining cognitive function in older adults: the Health ABC study. Neurology, 2009-06-09;72(23):2029-35. 2009-06-09 [PMID: 19506226] (Human)		Human
Murakami Y, Akahoshi T, Aoki N, Toyomoto M, Miyasaka N, Kohsaka H Intervention of an inflammation amplifier, triggering receptor expressed on myeloid cells 1, for treatment of autoimmune arthritis. Arthritis Rheum., 2009-06-01;60(6):1615-23. 2009-06-01 [PMID: 19479878] (Human)		Human
Khosravi R, Tran SD, Lambert M, O'Loughlin J, KÃƒÂ¢ K, Feine JS, Caron C, Tremblay A, Nicolau B Adiposity and gingival crevicular fluid tumour necrosis factor-alpha levels in children. J. Clin. Periodontol., 2009-03-11;36(4):301-7. 2009-03-11 [PMID: 19426176] (Human)		Human
Liao WT, Yu CL, Lan CC, Lee CH, Chang CH, Chang LW, You HL, Yu HS Differential effects of arsenic on cutaneous and systemic immunity: focusing on CD4+ cell apoptosis in patients with arsenic-induced Bowen's disease. Carcinogenesis, 2009-04-17;30(6):1064-72. 2009-04-17 [PMID: 19376847] (Human)		Human
Singh S, Singh R, Sharma PK, Singh UP, Rai SN, Chung LW, Cooper CR, Novakovic KR, Grizzle WE, Lillard JW Serum CXCL13 positively correlates with prostatic disease, prostate-specific antigen and mediates prostate cancer cell invasion, integrin clustering and cell adhesion. Cancer Lett., 2009-04-17;283(1):29-35. 2009-04-17 [PMID: 19375853] (Human)		Human
Glass-Marmor L, Paperna T, Galboiz Y, Miller A Immunomodulation by chronobiologically-based glucocorticoids treatment for multiple sclerosis relapses. J. Neuroimmunol., 2009-03-28;210(1):124-7. 2009-03-28 [PMID: 19329193] (Human)		Human
Cartier A, Cote M, Lemieux I, Perusse L, Tremblay A, Bouchard C, Despres JP Sex differences in inflammatory markers: what is the contribution of visceral adiposity? Am. J. Clin. Nutr., 2009-03-18;89(5):1307-14. 2009-03-18 [PMID: 19297456] (Human)		Human
Frankel DS, Vasan RS, D'Agostino RB, Benjamin EJ, Levy D, Wang TJ, Meigs JB Resistin, adiponectin, and risk of heart failure the Framingham offspring study. J. Am. Coll. Cardiol., 2008-12-26;53(9):754-62. 2008-12-26 [PMID: 19245965] (Human)		Human
Gombos T, Forhecz Z, Pozsonyi Z, Wallentin S, Papassotiriou J, Kunde J, Morgenthaler NG, Janoskuti L, Prohaszka Z Adrenomedullin and endothelin-1 are related to inflammation in chronic heart failure. Inflamm. Res., 2009-06-01;58(6):298-305. 2009-06-01 [PMID: 19212702] (Human)		Human
Troseid M, Seljeflot I, Hjerkinn EM, Arnesen H Interleukin-18 is a strong predictor of cardiovascular events in elderly men with the metabolic syndrome: synergistic effect of inflammation and hyperglycemia. Diabetes Care, 2008-12-17;32(3):486-92. 2008-12-17 [PMID: 19092166] (Human)		Human
Redmond EM, Morrow D, Kundimi S, Miller-Graziano CL, Cullen JP Acetaldehyde stimulates monocyte adhesion in a P-selectin- and TNFalpha-dependent manner. Atherosclerosis, 2008-10-18;204(2):372-80. 2008-10-18 [PMID: 19036374] (Human)		Human
Ogston NC, Karastergiou K, Hosseinzadeh-Attar MJ, Bhome R, Madani R, Stables M, Gilroy D, Flachs P, Hensler M, Kopecky J, Mohamed-Ali V Low-dose acetylsalicylic acid inhibits the secretion of interleukin-6 from white adipose tissue. Int J Obes (Lond), 2008-11-04;32(12):1807-15. 2008-11-04 [PMID: 18982014] (Human)		Human
Rihl M, Kellner H, Kellner W, Barthel C, Yu DT, Tak PP, Zeidler H, Baeten D Identification of interleukin-7 as a candidate disease mediator in spondylarthritis. Arthritis Rheum., 2008-11-01;58(11):3430-5. 2008-11-01 [PMID: 18975340] (Human)		Human
Poulsen TD, Andersen LW, Steinbruchel D, Gotze JP, Jorgensen OS, Olsen NV Two large preoperative doses of erythropoietin do not reduce the systemic inflammatory response to cardiac surgery. J. Cardiothorac. Vasc. Anesth., 2008-10-22;23(3):316-23. 2008-10-22 [PMID: 18948032] (Human)		Human
Kabagambe EK, Ordovas JM, Tsai MY, Borecki IB, Hopkins PN, Glasser SP, Arnett DK Smoking, inflammatory patterns and postprandial hypertriglyceridemia. Atherosclerosis, 2008-08-13;203(2):633-9. 2008-08-13 [PMID: 18804210] (Human)		Human
Barcelo-Coblijn G, Murphy EJ, Othman R, Moghadasian MH, Kashour T, Friel JK Flaxseed oil and fish-oil capsule consumption alters human red blood cell n-3 fatty acid composition: a multiple-dosing trial comparing 2 sources of n-3 fatty acid. Am. J. Clin. Nutr., 2008-09-01;88(3):801-9. 2008-09-01 [PMID: 18779299] (Human)		Human
Hothersall EJ, Chaudhuri R, McSharry C, Donnelly I, Lafferty J, McMahon AD, Weir CJ, Meiklejohn J, Sattar N, McInnes I, Wood S, Thomson NC Effects of atorvastatin added to inhaled corticosteroids on lung function and sputum cell counts in atopic asthma. Thorax, 2008-08-29;63(12):1070-5. 2008-08-29 [PMID: 18757458] (Human)		Human
Grann VR, Ziv E, Joseph CK, Neugut AI, Wei Y, Jacobson JS, Horwitz MS, Bowman N, Beckmann K, Hershman DL Duffy (Fy), DARC, and neutropenia among women from the United States, Europe and the Caribbean. Br. J. Haematol., 2008-08-15;143(2):288-93. 2008-08-15 [PMID: 18710383] (Human)		Human
O'Donnell K, Brydon L, Wright CE, Steptoe A Self-esteem levels and cardiovascular and inflammatory responses to acute stress. Brain Behav. Immun., 2008-07-08;0(0):. 2008-07-08 [PMID: 18644432] (Human)		Human
Tholstrup T, Raff M, Straarup EM, Lund P, Basu S, Bruun JM An oil mixture with trans-10, cis-12 conjugated linoleic acid increases markers of inflammation and in vivo lipid peroxidation compared with cis-9, trans-11 conjugated linoleic acid in postmenopausal women. J. Nutr., 2008-08-01;138(8):1445-51. 2008-08-01 [PMID: 18641189] (Human)		Human
Vgontzas AN, Zoumakis E, Bixler EO, Lin HM, Collins B, Basta M, Pejovic S, Chrousos GP Selective effects of CPAP on sleep apnoea-associated manifestations. Eur. J. Clin. Invest., 2008-08-01;38(8):585-95. 2008-08-01 [PMID: 18627419] (Human)		Human
Grann VR, Bowman N, Joseph C, Wei Y, Horwitz MS, Jacobson JS, Santella RP, Hershman DL Neutropenia in 6 ethnic groups from the Caribbean and the U.S. Cancer, 2008-08-15;113(4):854-60. 2008-08-15 [PMID: 18543314] (Human)		Human
Elsaid KA, Fleming BC, Oksendahl HL, Machan JT, Fadale PD, Hulstyn MJ, Shalvoy R, Jay GD Decreased lubricin concentrations and markers of joint inflammation in the synovial fluid of patients with anterior cruciate ligament injury. Arthritis Rheum., 2008-06-01;58(6):1707-15. 2008-06-01 [PMID: 18512776] (Human)		Human
Paulsson JM, Dadfar E, Held C, Jacobson SH, Lundahl J In vivo transmigrated monocytes from patients with stable coronary artery disease have a reduced expression of CD11b. Clin. Exp. Immunol., 2008-05-05;153(2):196-204. 2008-05-05 [PMID: 18460014] (Human)		Human
Denollet J, Vrints CJ, Conraads VM Comparing Type D personality and older age as correlates of tumor necrosis factor-alpha dysregulation in chronic heart failure. Brain Behav. Immun., 2008-02-20;22(5):736-43. 2008-02-20 [PMID: 18068948] (Human)		Human
Mayr FB, Spiel AO, Leitner JM, Firbas C, Kliegel T, Jilma-Stohlawetz P, Derendorf H, Jilma B Duffy antigen modifies the chemokine response in human endotoxemia. Crit. Care Med., 2008-01-01;36(1):159-65. 2008-01-01 [PMID: 18007272] (Human)		Human
Koivisto H, Hietala J, Anttila P, Niemela O Co-occurrence of IgA antibodies against ethanol metabolites and tissue transglutaminase in alcohol consumers: correlation with proinflammatory cytokines and markers of fibrogenesis. Dig. Dis. Sci., 2007-06-28;53(2):500-5. 2007-06-28 [PMID: 17597408] (Human)		Human
Vogiatzis I, Stratakos G, Simoes DC, Terzis G, Georgiadou O, Roussos C, Zakynthinos S Effects of rehabilitative exercise on peripheral muscle TNFalpha, IL-6, IGF-I and MyoD expression in patients with COPD. Thorax, 2007-06-15;62(11):950-6. 2007-06-15 [PMID: 17573449] (Human)		Human
Kissel CK, Lehmann R, Assmus B, Aicher A, Honold J, Fischer-Rasokat U, Heeschen C, Spyridopoulos I, Dimmeler S, Zeiher AM Selective functional exhaustion of hematopoietic progenitor cells in the bone marrow of patients with postinfarction heart failure. J. Am. Coll. Cardiol., 2007-06-04;49(24):2341-9. 2007-06-04 [PMID: 17572250] (Human)		Human
Cauley JA, Danielson ME, Boudreau RM, Forrest KY, Zmuda JM, Pahor M, Tylavsky FA, Cummings SR, Harris TB, Newman AB Inflammatory markers and incident fracture risk in older men and women: the Health Aging and Body Composition Study. J. Bone Miner. Res., 2007-07-01;22(7):1088-95. 2007-07-01 [PMID: 17419681] (Human)		Human
Sherman JA, Hall A, Malenka DJ, De Muinck ED, Simons M Humoral and cellular factors responsible for coronary collateral formation. Am. J. Cardiol., 2006-08-31;98(9):1194-7. 2006-08-31 [PMID: 17056326] (Human)		Human
Kalantar-Zadeh K, Brennan ML, Hazen SL Serum myeloperoxidase and mortality in maintenance hemodialysis patients. Am. J. Kidney Dis., 2006-07-01;48(1):59-68. 2006-07-01 [PMID: 16797387] (Human)		Human
Mysliwiec M, Zorena K, Balcerska A, Mysliwska J, Lipowski P, Raczynska K The activity of N-acetyl-beta-D-glucosaminidase and tumor necrosis factor-alpha at early stage of diabetic retinopathy development in type 1 diabetes mellitus children. Clin. Biochem., 2006-04-05;39(8):851-6. 2006-04-05 [PMID: 16696964] (Human)		Human
Steensberg A, Dalsgaard MK, Secher NH, Pedersen BK Cerebrospinal fluid IL-6, HSP72, and TNF-alpha in exercising humans. Brain Behav. Immun., 2006-05-02;20(6):585-9. 2006-05-02 [PMID: 16647242] (Human)		Human
Haukeland JW, Damas JK, Konopski Z, Loberg EM, Haaland T, Goverud I, Torjesen PA, Birkeland K, Bjoro K, Aukrust P Systemic inflammation in nonalcoholic fatty liver disease is characterized by elevated levels of CCL2. J. Hepatol., 2006-03-20;44(6):1167-74. 2006-03-20 [PMID: 16618517] (Human)		Human
Theurl I, Mattle V, Seifert M, Mariani M, Marth C, Weiss G Dysregulated monocyte iron homeostasis and erythropoietin formation in patients with anemia of chronic disease. Blood, 2006-01-24;107(10):4142-8. 2006-01-24 [PMID: 16434484] (Human)		Human
Leitner JM, Firbas C, Mayr FB, Reiter RA, Steinlechner B, Jilma B Recombinant human antithrombin inhibits thrombin formation and interleukin 6 release in human endotoxemia. Clin. Pharmacol. Ther., 2006-01-01;79(1):23-34. 2006-01-01 [PMID: 16413239] (Human)		Human
Iversen PO, Wiig H Tumor necrosis factor alpha and adiponectin in bone marrow interstitial fluid from patients with acute myeloid leukemia inhibit normal hematopoiesis. Clin. Cancer Res., 2005-10-01;11(19):6793-9. 2005-10-01 [PMID: 16203766] (Human)		Human
Kaneyama K, Segami N, Sun W, Sato J, Fujimura K Analysis of tumor necrosis factor-alpha, interleukin-6, interleukin-1beta, soluble tumor necrosis factor receptors I and II, interleukin-6 soluble receptor, interleukin-1 soluble receptor type II, interleukin-1 receptor antagonist, and protein in the synovial fluid of patients with temporomandibular joint disorders. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 2005-03-01;99(3):276-84. 2005-03-01 [PMID: 15716832] (Human)		Human
Sadeghi M, Daniel V, Naujokat C, Wiesel M, Hergesell O, Opelz G Strong inflammatory cytokine response in male and strong anti-inflammatory response in female kidney transplant recipients with urinary tract infection. Transpl. Int., 2005-02-01;18(2):177-85. 2005-02-01 [PMID: 15691270] (Human)		Human
Jensen J, Krakauer M, Sellebjerg F Cytokines and adhesion molecules in multiple sclerosis patients treated with interferon-beta1b. Cytokine, 2005-01-07;29(1):24-30. 2005-01-07 [PMID: 15579375] (Human)		Human
Attallah AM, Ibrahim GG Immunodetection of a hepatitis C virus (HCV) antigen and Thl/Th2 cytokines in cerebrospinal fluid of meningitis patients. J Immunoassay Immunochem, 2004-01-01;25(4):313-20. 2004-01-01 [PMID: 15552586] (Human)		Human
Alter P, Maisch B Escape from cardiomyocyte apoptosis by enterovirus persistence due to elevated soluble Fas-receptors. Z Kardiol, 2004-07-01;93(7):524-32. 2004-07-01 [PMID: 15243763] (Human)		Human
Garey KW, Neuhauser MM, Robbins RA, Danziger LH, Rubinstein I Markers of inflammation in exhaled breath condensate of young healthy smokers. Chest, 2004-01-01;125(1):22-6. 2004-01-01 [PMID: 14718416] (Human)		Human
Oddy WH, Halonen M, Martinez FD, Lohman IC, Stern DA, Kurzius-Spencer M, Guerra S, Wright AL TGF-beta in human milk is associated with wheeze in infancy. J. Allergy Clin. Immunol., 2003-10-01;112(4):723-8. 2003-10-01 [PMID: 14564350] (Human)		Human
Bergholm R, Leirisalo-Repo M, Vehkavaara S, Makimattila S, Taskinen MR, Yki-Jarvinen H Impaired responsiveness to NO in newly diagnosed patients with rheumatoid arthritis. Arterioscler. Thromb. Vasc. Biol., 2002-10-01;22(10):1637-41. 2002-10-01 [PMID: 12377742] (Human)		Human
Schulz O, 2019, Sigusch HH Impact of an exercise-induced increase in cardiac troponin I in chronic heart failure secondary to ischemic or idiopathic dilated cardiomyopathy. e0216744, 2002-09-01;90(5):547-50. 2002-09-01 [PMID: 12208423] (Human)		Human
Capalbo S, Battista C, Delia M, Ciancio A, De Santis G, Dargenio M, Diomede D, Liso V Evaluation of tumor necrosis factor-alpha and erythropoietin serum levels in B-cell chronic lymphocytic leukemia patients with anemia. Acta Haematol., 2002-01-01;108(2):84-9. 2002-01-01 [PMID: 12187026] (Human)		Human
Schumacher A, Seljeflot I, Lerkerod AB, Sommervoll L, Otterstad JE, Arnesen H Positive Chlamydia pneumoniae serology is associated with elevated levels of tumor necrosis factor alpha in patients with coronary heart disease. Atherosclerosis, 2002-09-01;164(1):153-60. 2002-09-01 [PMID: 12119204] (Human)		Human
Rooney M, Varsani H, Martin K, Lombard PR, Dayer JM, Woo P Tumour necrosis factor alpha and its soluble receptors in juvenile chronic arthritis. Rheumatology (Oxford), 2000-04-01;39(4):432-8. 2000-04-01 [PMID: 10817778] (Human)		Human
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FAQs for TNF-alpha (HSTA00E). (Showing 1 - 4 of 4 FAQs).

I need to know about TNF-alpha antibody kits for mice.
- We currently have two TNFalpha ELISA kits specific for mouse: catalog numbers KA0257 and NBP1-92670.
I would like to ask you for help. I need an antibody for Elisa to detect human TNF alpha in a supernatant from a cell culture (meaning supernatant after centrifugation of collected cell suspension from a plate well). Which of your antibodies against human tnf alpha would be suitable? I would like to buy only the primary antibody.
- I would recommend catalog number NBP1-67821 or NB600-587; however, a full list of our anti-human TNF alpha antibodies suitable for use in ELISA can be found using this link.
I am interested in a TNF alpha antibody, cross reactive for human, rat and mouse (host species: rabbit). Could your product NBP1-19532 be used in western blotting applications? Or do you have a similar product in your catalog which could fit with my request?
- The antibody you mention, NBP1-19532, has not yet been validated in Western blot. I would instead recommend either NBP1-67821 or NB600-587. These are both rabbit polyclonal antibodies that cross-reacts with human, mouse and rat and have been used in Western blotting.
Can your TNF-alpha products be used to treat TBI victims and therefore avoid the perispinal injections with Enbrel?
- I am very sorry, but all of our products are for scientific research use only, and none are intended or approved for use in humans.

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By Hunter MartinezThe paradigm shifting view of the immune system being leveraged to target cancer has led to numerous therapeutic breakthroughs. One major cell group responsible for this revelation is a T cell. ... Read full blog post.

Immune Cell Metabolic Flux Influences Type I Diabetes
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Liver ASK1 activates autophagy to protect against hepatic fat accumulation, non-alcoholic steatohepatitis and fibrosis
By Jamshed Arslan, Pharm. D., PhD. The most common chronic liver disorder worldwide is non-alcoholic fatty liver disease (NAFLD). This obesity-linked disorder can manifest as hepatic fat accumulation (steatosis) wit... Read full blog post.

Metabolic Syndrome: Symptoms and associated disease states
By Jamshed Arslan, Pharm. D., PhD. What is metabolic syndrome?It was 1988 when, after decades of research, Dr. GM Reaven of the Stanford University, CA, explained the relationship between four diseases:... Read full blog post.

Increased wild type FUS levels in ALS patients lead to a toxic microenvironment and motor neuron neurodegeneration
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1 µg/lane of Recombinant Human TNF-alpha was resolved by SDS-PAGE with silver staining, under reducing (R) conditions, showing a band at 17 kDa.

TNF-alpha [Unconjugated]
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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Human TNF-alpha Quantikine HS ELISA

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Publications for TNF-alpha (HSTA00E)(255)

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FAQs for TNF-alpha (HSTA00E). (Showing 1 - 4 of 4 FAQs).

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