Human TFF3 Quantikine ELISA Kit

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

TFF3 (Trefoil Factor 3), also known as ITF and P1.B, is a peptide that plays an important role in epithelial regeneration and wound healing. It can form disulfide-linked dimers or associate into disulfide-linked complexes with the intestinal mucous proteins FCGBP and MUC-2. TFF3 is expressed by epithelial goblet cells in the respiratory tract, biliary and breast ducts, small and large intestine, and cardia of the stomach as well as by chondrocytes during bone development. TFF3 is upregulated in response to gastrointestinal epithelial disruptions and promotes epithelial wound healing. It enhances tumor cell invasion and metastasis by supporting hypoxia-induced VEGF upregulation.

We have publications tested in 2 confirmed species: Human, Xenograft.

Showing Publications 1 - 8 of 8.

Publications using DTFF30	Applications	Species
Rogulska, K;Wojciechowska-Koszko, I;Krasnod?bska-Szponder, B;Kwiatkowski, P;Roszkowska, P;Do??gowska, B;?uczkowska, K;Machali?ski, B;Kosik-Bogacka, D; TFF3 as a Diagnostic Biomarker in Kidney Transplant Patients International journal of molecular sciences 2023-07-25 [PMID: 37569301] (Human)		Human
MM Hasan, MA Gazi, S Das, SM Fahim, F Hossaini, AR Khan, J Ferdous, MA Alam, M Mahfuz, T Ahmed Gut biomolecules (I-FABP, TFF3 and lipocalin-2) are associated with linear growth and biomarkers of environmental enteric dysfunction (EED) in Bangladeshi children Scientific Reports, 2022-08-16;12(1):13905. 2022-08-16 [PMID: 35974137] (Human)		Human
F Cheng, X Wang, YS Chiou, C He, H Guo, YQ Tan, B Basappa, T Zhu, V Pandey, PE Lobie Trefoil factor 3 promotes pancreatic carcinoma progression via WNT pathway activation mediated by enhanced WNT ligand expression Cell Death & Disease, 2022-03-25;13(3):265. 2022-03-25 [PMID: 35332126] (Human)		Human
RM Chen, YS Chiou, QY Chong, HM Poh, TZ Tan, MY Zhang, L Ma, T Zhu, V Pandey, Basappa, AP Kumar, PE Lobie Pharmacological Inhibition of TFF3 Enhances Sensitivity of CMS4 Colorectal Carcinoma to 5-Fluorouracil through Inhibition of p44/42 MAPK Int J Mol Sci, 2019-12-09;20(24):. 2019-12-09 [PMID: 31835445] (Xenograft)		Xenograft
K Krüger, S Schmid, F Paulsen, A Ignatius, P Klinger, T Hotfiel, B Swoboda, K Gelse Trefoil Factor 3 (TFF3) Is Involved in Cell Migration for Skeletal Repair Int J Mol Sci, 2019-09-01;20(17):. 2019-09-01 [PMID: 31480518] (Human)		Human
R Nakov, T Velikova, V Nakov, G Ianiro, V Gerova, L Tankova Serum trefoil factor 3 predicts disease activity in patients with ulcerative colitis Eur Rev Med Pharmacol Sci, 2019-01-01;23(2):788-794. 2019-01-01 [PMID: 30720187] (Human)		Human
T Shimura, H Iwasaki, M Kitagawa, M Ebi, T Yamada, T Yamada, T Katano, H Nisie, Y Okamoto, K Ozeki, T Mizoshita, H Kataoka Urinary Cysteine-Rich Protein 61 and Trefoil Factor 3 as Diagnostic Biomarkers for Colorectal Cancer Transl Oncol, 2019-01-03;12(3):539-544. 2019-01-03 [PMID: 30611902] (Human)		Human
Lebherz-Eichinger D, Tudor B, Ankersmit H, Reiter T, Haas M, Roth-Walter F, Krenn C, Roth G Trefoil Factor 1 Excretion Is Increased in Early Stages of Chronic Kidney Disease. PLoS ONE, 2015-09-21;10(9):e0138312. 2015-09-21 [PMID: 26390128] (Human)		Human

Array DTFF30

• TFF3 Antibodies
• TFF3 ELISA Kits
• TFF3 Proteins
• TFF3 Proteins and Enzyme
• TFF3 ELISAs