Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Human Phospho-FGFR4 DuoSet IC ELISA, 2 Plate
CD334 antigen
CD334
EC 2.7.10
EC 2.7.10.1
FGF R4
FGFR4
FGFR-4
fibroblast growth factor receptor 4
JTK2hydroxyaryl-protein kinase
MGC20292
protein-tyrosine kinase
TKF
tyrosine kinase related to fibroblast growth factor receptor
tyrosylprotein kinase
Background
FGF activity is mediated by a family of type I transmembrane tyrosine kinases, which undergo dimerization and autophosphorylation after ligand binding. Five distinct genes encode closely related FGF receptors, FGF R1 through 5. FGF Rs contain three Ig-like domains and a stretch of acidic residues between the first and second Ig-like domains. FGF R1, 2, 3, and -4 have a cytoplasmic split tyrosine-kinase domain, but FGF R5 does not. Multiple forms of FGF R1, 2, and 3 are generated by alternative splicing