Human/Mouse/Rat Activin A Quantikine ELISA Kit

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications ELISA
Conjugate
HRP

Order Details

Human/Mouse/Rat Activin A Quantikine ELISA Kit Summary

Background
The Quantikine Human/Mouse/Rat Activin A Immunoassay is a 5.0 hour solid-phase ELISA designed to measure Activin A in human, mouse, or rat cell culture supernates, serum, plasma, and saliva. It contains CHO cell-expressed recombinant human/mouse/rat Activin A and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human/mouse/rat Activin A showed li...near curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally expressed Activin A.
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Specificity
Natural and recombinant human, mouse, and rat Activin A
Source
N/A
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
INHBA

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using
DAC00B in the following applications:

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human/Mouse/Rat Activin A Quantikine ELISA Kit

  • Activin A
  • activin AB alpha polypeptide
  • Activin beta-A chain
  • erythroid differentiation factor
  • Erythroid differentiation protein
  • follicle-stimulating hormone-releasing protein
  • FSH-releasing protein
  • inhibin beta A chain
  • inhibin beta A subunit
  • Inhibin, beta-1

Background

Activins, members of the TGF-beta superfamily, are disulfide-linked dimeric proteins originally purified from gonadal fluids as proteins that stimulated pituitary follicle stimulating hormone (FSH) release. Activin proteins have a wide range of biological activities, including mesoderm induction, neural cell differentiation, bone remodeling, hematopoiesis and roles in reproductive physiology. Activin isoforms and other members of the TGF-beta superfamily exert their biological effects by binding to heteromeric complexes of a type I and a type II serine-threonine kinase receptor, both of which are essential for signal transduction.

Activins are homodimers or heterodimers of the various beta subunit isoforms, while inhibins are heterodimers of a unique alpha subunit and one of the various beta subunits. Five beta subunits (mammalian beta A, beta B, beta C, beta E and Xenopus beta D) have been cloned to date. The activin/inhibin nomenclature reflects the subunit composition of the proteins: Activin A (beta A - beta A), Activin B (beta B - beta B), Activin AB (beta A - beta B), Inhibin A (alpha - beta A) and Inhibin B (alpha - beta B).

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for Activin A (DAC00B)(64)

We have publications tested in 7 confirmed species: Human, Mouse, Rat, N/A, Ovine, Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque), Transgenic Mouse.

We have publications tested in 1 application: ELISA Capture.


Filter By Application
ELISA Capture
(1)
All Applications
Filter By Species
Human
(45)
Mouse
(19)
Rat
(4)
N/A
(1)
Ovine
(1)
Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
(1)
Transgenic Mouse
(1)
All Species
Showing Publications 1 - 10 of 64. Show All 64 Publications.
Publications using DAC00B Applications Species
Sinn, K;Elbeialy, A;Mosleh, B;Aigner, C;Schelch, K;Laszlo, V;Dome, B;Hoda, MA;Grusch, M; High circulating activin A plasma levels are associated with tumour stage and poor survival in treatment-naive lung squamous cell cancer patients Translational oncology 2024-10-14 [PMID: 39405924] (Human) Human
Moqaddam, MA;Nemati, M;Dara, MM;Hoteit, M;Sadek, Z;Ramezani, A;Rand, MK;Abbassi-Daloii, A;Pashaei, Z;Almaqhawi, A;Razi, O;Escobar, KA;Supriya, R;Saeidi, A;Zouhal, H; Exploring the Impact of Astaxanthin Supplementation in Conjunction with a 12-Week CrossFit Training Regimen on Selected Adipo-Myokines Levels in Obese Males Nutrients 2024-08-26 [PMID: 39275173] (Human) Human
Nieuwenhuizen, NE;Nouailles, G;Sutherland, JS;Zyla, J;Pasternack, AH;Heyckendorf, J;Frye, BC;Höhne, K;Zedler, U;Bandermann, S;Abu Abed, U;Brinkmann, V;Gutbier, B;Witzenrath, M;Suttorp, N;Zissel, G;Lange, C;Ritvos, O;Kaufmann, SHE;CAPNETZ Study group, ;DZIF TB study group, ; Activin A levels are raised during human tuberculosis and blockade of the activin signaling axis influences murine responses to M. tuberculosis infection mBio 2024-02-20 [PMID: 38376260] (Human, Mouse) Human, Mouse
Aversa, Z;White, TA;Heeren, AA;Hulshizer, CA;Saul, D;Zhang, X;Molina, AJA;Redman, LM;Martin, CK;Racette, SB;Huffman, KM;Bhapkar, M;Khosla, S;Das, SK;Fielding, RA;Atkinson, EJ;LeBrasseur, NK; Calorie restriction reduces biomarkers of cellular senescence in humans Aging cell 2023-11-14 [PMID: 37961856] (Human) Human
St Sauver, JL;Weston, SA;Atkinson, EJ;Mc Gree, ME;Mielke, MM;White, TA;Heeren, AA;Olson, JE;Rocca, WA;Palmer, AK;Cummings, SR;Fielding, RA;Bielinski, SJ;LeBrasseur, NK; Biomarkers of cellular senescence and risk of death in humans Aging cell 2023-10-06 [PMID: 37803875] (Human) Human
Yang, YS;Lin, C;Ma, H;Xie, J;Kaplan, FS;Gao, G;Shim, JH; AAV-Mediated Targeting of the Activin A-ACVR1R206H Signaling in Fibrodysplasia Ossificans Progressiva Biomolecules 2023-09-08 [PMID: 37759764] (Transgenic Mouse, Human) Transgenic Mouse, Human
Koczo, A;Hauspurg, A;Countouris, ME;Berlacher, KL;Özbay, B;Hanley-Yanez, K;Catov, J; Immune Markers, Blood Pressure Severity, and Cardiac Remodeling 1 to 2?Years After Hypertensive Disorders of Pregnancy Journal of the American Heart Association 2023-10-03 [PMID: 37750579] (Human) Human
Mendis, BL;He, Z;Li, X;Wang, J;Li, C;Li, P; Acoustic Atomization-Induced Pumping Based on a Vibrating Sharp-Tip Capillary Micromachines 2023-06-08 [PMID: 37374797] (N/A) N/A
Z Aversa, EJ Atkinson, EM Carmona, TA White, AA Heeren, SK Jachim, X Zhang, SR Cummings, SE Chiarella, AH Limper, NK LeBrasseur Biomarkers of cellular senescence in idiopathic pulmonary fibrosis Respiratory Research, 2023-04-07;24(1):101. 2023-04-07 [PMID: 37029417] (Human) Human
AL Queiroz, E Dantas, S Ramsamooj, A Murthy, M Ahmed, ERM Zunica, RJ Liang, J Murphy, CD Holman, CJ Bare, G Ghahramani, Z Wu, DE Cohen, JP Kirwan, LC Cantley, CL Axelrod, MD Goncalves Blocking ActRIIB and restoring appetite reverses cachexia and improves survival in mice with lung cancer Nature Communications, 2022-08-08;13(1):4633. 2022-08-08 [PMID: 35941104] (Human) Human
Show All 64 Publications.

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Bioinformatics

Gene Symbol INHBA