Human IL-31 DuoSet ELISA, 15 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Interleukin 31 (IL-31) is a secreted, T-cell-derived, 24-kDa, short-chain member of the alpha-helical family of cytokines. The mature region is 141 amino acids (aa) in length and exhibits four alpha-helices. Human and mouse IL-31 are highly divergent at 24% aa sequence identity. The receptor for IL-31 is found on keratinocytes and monocytes. It is a heterodimer composed of the Oncostatin M receptor and a novel gp130-related molecule. IL-31 may be involved in pruritis, or skin itching.

We have publications tested in 2 confirmed species: Human, Mouse.

Showing Publications 1 - 8 of 8.

Publications using DY2824	Applications	Species
D Tortolani, C Di Meo, S Standoli, F Ciaramella, S Kadhim, E Hsu, C Rapino, M Maccarrone Rare Phytocannabinoids Exert Anti-Inflammatory Effects on Human Keratinocytes via the Endocannabinoid System and MAPK Signaling Pathway International Journal of Molecular Sciences, 2023-02-01;24(3):. 2023-02-01 [PMID: 36769042] (Human)		Human
R Kishi, S Toyama, M Tominaga, Y Kamata, E Komiya, T Kaneko, Y Suga, K Takamori Effects of Dupilumab on Itch-Related Events in Atopic Dermatitis: Implications for Assessing Treatment Efficacy in Clinical Practice Cells, 2023-01-05;12(2):. 2023-01-05 [PMID: 36672173] (Human)		Human
D Parashar, A Geethadevi, MR Aure, J Mishra, J George, C Chen, MK Mishra, A Tahiri, W Zhao, B Nair, Y Lu, LS Mangala, C Rodriguez-, G Lopez-Bere, AKS Camara, M Liang, JS Rader, R Ramchandra, M You, AK Sood, VN Kristensen, GB Mills, S Pradeep, P Chaluvally miRNA551b-3p Activates an Oncostatin Signaling Module for the Progression of Triple-Negative Breast Cancer Cell Rep, 2019-12-24;29(13):4389-4406.e10. 2019-12-24 [PMID: 31875548] (Human)		Human
MC Kang, K Cho, JH Lee, L Subedi, S Yumnam, SY Kim Effect of Resveratrol-Enriched Rice on Skin Inflammation and Pruritus in the NC/Nga Mouse Model of Atopic Dermatitis Int J Mol Sci, 2019-03-21;20(6):. 2019-03-21 [PMID: 30901835] (Mouse)		Mouse
K Yamamura, T Uruno, A Shiraishi, Y Tanaka, M Ushijima, T Nakahara, M Watanabe, M Kido-Nakah, I Tsuge, M Furue, Y Fukui The transcription factor EPAS1 links DOCK8 deficiency to atopic skin inflammation via IL-31 induction Nat Commun, 2017-01-09;8(0):13946. 2017-01-09 [PMID: 28067314] (Human)		Human
Tseng W, Lo M, Guo M, Hsieh K, Chang W, Kuo H IL-31 associated with coronary artery lesion formation in Kawasaki disease. PLoS ONE, 2014-08-14;9(8):e105195. 2014-08-14 [PMID: 25122210] (Human)		Human
Kim S, Kim HJ, Yang HS IL-31 Serum Protein and Tissue mRNA Levels in Patients with Atopic Dermatitis. Ann Dermatol, 2011-11-03;23(4):468-73. 2011-11-03 [PMID: 22148014] (Human)		Human
Raap U, Wichmann K, Bruder M, Stander S, Wedi B, Kapp A, Werfel T Correlation of IL-31 serum levels with severity of atopic dermatitis. J. Allergy Clin. Immunol., 2008-08-01;122(2):421-3. 2008-08-01 [PMID: 18678344] (Human)		Human

Array DY2824

• IL-31 Antibodies
• IL-31 Lysate
• IL-31 Proteins
• IL-31 Proteins and Enzymes
• IL-31 ELISA