Human IL-23 Quantikine ELISA Kit

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

IL-23 (Interleukin-23) is a disulfide-linked cytokine composed of a p19 subunit that is unique to IL-23 and a p40 subunit that is shared with IL-12. It is produced by activated macrophages, microglia, and monocyte-derived dendritic cells in response to pathogens. IL-23 induces the earliest recruitment of neutrophils to the site of infection and promotes the development and maintenance of Th17 cells. It also enhances the development of Th17 mediated autoimmunity and tumor progression. IL-23 signals through a receptor complex consisting of IL-12 R beta 1 and IL-23 R. This complex is expressed in mouse Th1 and Th2 cells, bone marrow dendritic cells, activated macrophages and CD4+ CD45Rb(low) memory T cells.

We have publications tested in 1 confirmed species: Human.

Showing Publications 1 - 10 of 34. Show All 34 Publications. Collapse Publications.

Publications using D2300B	Applications	Species
Melgar-Rodríguez, S;Polanco, A;Ríos-Muñoz, J;García, M;Sierra-Cristancho, A;González-Osuna, L;Díaz-Zúñiga, J;Carvajal, P;Vernal, R;Bravo, D; Differential Response of Human Dendritic Cells upon Stimulation with Encapsulated or Non-Encapsulated Isogenic Strains of Porphyromonas gingivalis International journal of molecular sciences 2024-04-20 [PMID: 38674095] (Human)		Human
D Wang, Y Lin, F Xu, H Zhang, X Zhu, Z Liu, Y Hu, G Dong, B Sun, Y Yu, G Ma, Z Tang, D Legarda, A Ting, Y Liu, J Hou, L Dong, H Xiong SIRPalpha maintains macrophage homeostasis by interacting with PTK2B kinase in Mycobacterium tuberculosis infection and through autophagy and necroptosis EBioMedicine, 2022-10-03;85(0):104278. 2022-10-03 [PMID: 36202053] (Human)		Human
J Milosevic, M Jurisevic, V Grbovic, I Jovanovic, N Gajovic, A Jurisic-Sk Potential Protective Role of Galectin-3 in Patients with Gonarthrosis and Diabetes Mellitus: A Cross-Sectional Study International Journal of Environmental Research and Public Health, 2022-09-13;19(18):. 2022-09-13 [PMID: 36141752] (Human)		Human
N Millet, NV Solis, D Aguilar, MS Lionakis, RT Wheeler, N Jendzjowsk, M Swidergall IL-23 signaling prevents ferroptosis-driven renal immunopathology during candidiasis Nature Communications, 2022-09-22;13(1):5545. 2022-09-22 [PMID: 36138043] (Human)		Human
Q Su, L Zhang, Z Qi, B Huang The Mechanism of Inflammatory Factors and Soluble Vascular Cell Adhesion Molecule-1 Regulated by Nuclear Transcription Factor NF-kappaB in Unstable Angina Pectoris Journal of Immunology Research, 2022-07-30;2022(0):6137219. 2022-07-30 [PMID: 35942210] (Human)		Human
A Weber, A Schwiebs, H Solhaug, J Stenvik, AM Nilsen, M Wagner, B Relja, HH Radeke Nanoplastics affect the inflammatory cytokine release by primary human monocytes and dendritic cells Environment international, 2022-03-15;163(0):107173. 2022-03-15 [PMID: 35303527] (Human)		Human
HA Al-Rawaf, AH Alghadir, SA Gabr Expression of Circulating MicroRNAs and Myokines and Interactions with Serum Osteopontin in Type 2 Diabetic Patients with Moderate and Poor Glycemic Control: A Biochemical and Molecular Study BioMed Research International, 2021-12-07;2021(0):7453000. 2021-12-07 [PMID: 34917685] (Human)		Human
LA Lucaciu, M Ilie?, ?C Vesa, R Seicean, S Din, CA Iuga, A Seicean Serum Interleukin (IL)-23 and IL-17 Profile in Inflammatory Bowel Disease (IBD) Patients Could Differentiate between Severe and Non-Severe Disease Journal of personalized medicine, 2021-11-02;11(11):. 2021-11-02 [PMID: 34834482] (Human)		Human
VR Ribeiro, M Romao-Veig, PR Nunes, ML Matias, JC Peracoli, MTS Peracoli Vitamin D modulates the transcription factors of T cell subsets to anti-inflammatory and regulatory profiles in preeclampsia International immunopharmacology, 2021-11-20;0(0):108366. 2021-11-20 [PMID: 34810124] (Human)		Human
K Pawlak-Bu?, W Schmidt, P Leszczy?sk Lack of Association between Serum Interleukin-23 and Interleukin-27 Levels and Disease Activity in Patients with Active Systemic Lupus Erythematosus Journal of Clinical Medicine, 2021-10-19;10(20):. 2021-10-19 [PMID: 34682911] (Human)		Human
E Jahaj, AG Vassiliou, C Keskinidou, P Gallos, CS Vrettou, S Tsipilis, Z Mastora, SE Orfanos, I Dimopoulou, A Kotanidou Evaluating the Role of the Interleukin-23/17 Axis in Critically Ill COVID-19 Patients Journal of personalized medicine, 2021-09-07;11(9):. 2021-09-07 [PMID: 34575667] (Human)		Human
C Zhang, C Xu, L Gao, X Li, C Zhao Porphyromonas gingivalis lipopolysaccharide promotes T-hel per17 cell differentiation by upregulating Delta-like ligand 4 expression on CD14+ monocytes PeerJ, 2021-04-23;9(0):e11094. 2021-04-23 [PMID: 33981487] (Human)		Human
M Ga?ecka, K Bli?niewsk, A Orzechowsk, J Szemraj, M Maes, M Berk, KP Su, P Ga?ecki Inflammatory versus Anti-inflammatory Profiles in Major Depressive Disorders-The Role of IL-17, IL-21, IL-23, IL-35 and Foxp3 Journal of personalized medicine, 2021-01-23;11(2):. 2021-01-23 [PMID: 33498653] (Human)		Human
Gao Y, Sun W, Cha X, Wang H 'Psoriasis 1' reduces T‑lymphocyte‑mediated inflammation in patients with psoriasis by inhibiting vitamin D receptor‑mediated STAT4 inactivation. Int J Mol Med, 2020-08-06;46(4):1538-1550. 2020-08-06 [PMID: 32945358] (Human)		Human
MM Abhyankar, JZ Ma, KW Scully, AJ Nafziger, AL Frisbee, MM Saleh, GR Madden, AR Hays, M Poulter, WA Petri Immune Profiling To Predict Outcome of Clostridioides difficile Infection MBio, 2020-05-26;11(3):. 2020-05-26 [PMID: 32457246] (Human)		Human
H Yu, S Cui, Y Mei, Q Li, L Wu, S Duan, G Cai, H Zhu, B Fu, L Zhang, Z Feng, X Chen Mesangial Cells Exhibit Features of Antigen-Presenting Cells and Activate CD4+ T Cell Responses J Immunol Res, 2019-06-17;2019(0):2121849. 2019-06-17 [PMID: 31317046] (Human)		Human
JK Sun, WH Zhang, WX Chen, X Wang, XW Mu Effects of early enteral nutrition on Th17/Treg cells and IL-23/IL-17 in septic patients World J. Gastroenterol., 2019-06-14;25(22):2799-2808. 2019-06-14 [PMID: 31236002] (Human)		Human
S Clayton, E Cauble, A Kumar, N Patil, D Ledford, N Kolliputi, MF Lopes-Vire, D Castell, J Richter Plasma levels of TNF-?, IL-6, IFN-?, IL-12, IL-17, IL-22, and IL-23 in achalasia, eosinophilic esophagitis (EoE), and gastroesophageal reflux disease (GERD) BMC Gastroenterol, 2019-02-11;19(1):28. 2019-02-11 [PMID: 30744559] (Human)		Human
C Guida, SD Stephen, M Watson, N Dempster, P Larraufie, T Marjot, T Cargill, L Rickers, M Pavlides, J Tomlinson, JFL Cobbold, CM Zhao, D Chen, F Gribble, F Reimann, R Gillies, B Sgromo, P Rorsman, JD Ryan, RD Ramracheya PYY plays a key role in the resolution of diabetes following bariatric surgery in humans EBioMedicine, 2019-01-11;0(0):. 2019-01-11 [PMID: 30639417] (Human)		Human
N Ma, Q Tang, WT Wu, XA Huang, Q Xu, GL Rong, S Chen, JP Song Three Constituents of Moringa oleifera Seeds Regulate Expression of Th17-Relevant Cytokines and Ameliorate TPA-Induced Psoriasis-Like Skin Lesions in Mice Molecules, 2018-12-10;23(12):. 2018-12-10 [PMID: 30544700] (Human)		Human
T Zheng, C Xu, C Mao, X Mou, F Wu, X Wang, L Bu, Y Zhou, X Luo, Q Lu, H Liu, G Yuan, S Wang, D Chen, Y Xiao Increased Interleukin-23 in Hashimoto's Thyroiditis Disease Induces Autophagy Suppression and Reactive Oxygen Species Accumulation Front Immunol, 2018-01-29;9(0):96. 2018-01-29 [PMID: 29434604] (Human)		Human
L Srinivasan, L Kilpatrick, SS Shah, S Abbasi, MC Harris Elevations of novel cytokines in bacterial meningitis in infants PLoS ONE, 2018-02-02;13(2):e0181449. 2018-02-02 [PMID: 29394248] (Human)		Human
G Schmalz, I Davarpanah, J Jäger, RF Mausberg, B Krohn-Grim, J Schmidt, R Haak, U Sack, D Ziebolz MMP-8 and TIMP-1 are associated to periodontal inflammation in patients with rheumatoid arthritis under methotrexate immunosuppression - First results of a cross-sectional study J Microbiol Immunol Infect, 2017-09-04;0(0):. 2017-09-04 [PMID: 28919284] (Human)		Human
Z Meng, Y Zhang, Z Wei, P Liu, J Kang, Y Zhang, D Ma, C Ke, Y Chen, J Luo, Z Gong High serum resistin associates with intrahepatic inflammation and necrosis: an index of disease severity for patients with chronic HBV infection BMC Gastroenterol, 2017-01-07;17(1):6. 2017-01-07 [PMID: 28061755] (Human)		Human
Jennifer L Liedel Effects of anticipated neonatal surgical intervention on maternal milk cytokine production J. Pediatr. Surg., 2016-10-27;0(0):. 2016-10-27 [PMID: 27836369] (Human)		Human
Ofer Levy Age-Specific Adjuvant Synergy: Dual TLR7/8 and Mincle Activation of Human Newborn Dendritic Cells Enables Th1 Polarization J. Immunol., 2016-10-28;0(0):. 2016-10-28 [PMID: 27793997] (Human)		Human
Serum Interleukin-18, Fetuin-A, Soluble Intercellular Adhesion Molecule-1, and Endothelin-1 in Ankylosing Spondylitis, Psoriatic Arthritis, and SAPHO Syndrome Int J Mol Sci, 2016-08-03;17(8):. 2016-08-03 [PMID: 27527149] (Human)		Human
Loubaki L, Hadj-Salem I, Fakhfakh R, Jacques E, Plante S, Boisvert M, Aoudjit F, Chakir J Co-culture of human bronchial fibroblasts and CD4+ T cells increases Th17 cytokine signature. PLoS ONE, 2013-12-05;8(12):e81983. 2013-12-05 [PMID: 24349168] (Human)		Human
Grivennikov S, Wang K, Mucida D, Stewart C, Schnabl B, Jauch D, Taniguchi K, Yu G, Osterreicher C, Hung K, Datz C, Feng Y, Fearon E, Oukka M, Tessarollo L, Coppola V, Yarovinsky F, Cheroutre H, Eckmann L, Trinchieri G, Karin M Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth. Nature, 2012-11-08;491(7423):254-8. 2012-11-08 [PMID: 23034650] (Human)		Human
Nakajima H, Nakajima K, Tarutani M, Morishige R, Sano S Kinetics of circulating Th17 cytokines and adipokines in psoriasis patients. Arch. Dermatol. Res., 2011-06-17;303(6):451-5. 2011-06-17 [PMID: 21681565] (Human)		Human
Song W, Tai YT, Tian Z, Hideshima T, Chauhan D, Nanjappa P, Exley MA, Anderson KC, Munshi NC HDAC inhibition by LBH589 affects the phenotype and function of human myeloid dendritic cells. Leukemia, 2010-11-19;25(1):161-8. 2010-11-19 [PMID: 21102427] (Human)		Human
Legat A, Thomas S, Hermand P, Van Mechelen M, Goldman M, De Wit D CD14-independent responses induced by a synthetic lipid A mimetic. Eur J Immunol, 2010-03-01;40(3):797-802. 2010-03-01 [PMID: 20039305] (Human)		Human
Eid RE, Rao DA, Zhou J, Lo SF, Ranjbaran H, Gallo A, Sokol SI, Pfau S, Pober JS, Tellides G Interleukin-17 and interferon-gamma are produced concomitantly by human coronary artery-infiltrating T cells and act synergistically on vascular smooth muscle cells. Circulation, 2009-03-02;119(10):1424-32. 2009-03-02 [PMID: 19255340] (Human)		Human
Chi W, Zhu X, Yang P, Liu X, Lin X, Zhou H, Huang X, Kijlstra A Upregulated IL-23 and IL-17 in Behcet patients with active uveitis. Invest. Ophthalmol. Vis. Sci., 2008-07-01;49(7):3058-64. 2008-07-01 [PMID: 18579762] (Human)		Human
Show All 34 Publications. Collapse Publications.

Array D2300B

• IL-23A/IL-23 P19 Antibodies
• IL-23A/IL-23 P19 Lysate
• IL-23A/IL-23 P19 Proteins
• IL-23A/IL-23 P19 ELISAs
• IL-23A/IL-23 P19 Proteins and Enzymes