Human HGF DuoSet ELISA, 15 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

HGF (Hepatocyte Growth Factor, Scatter Factor) induces the proliferation and migration of epithelial cells, hepatocytes, chondrocytes, keratinocytes, melanocytes, endothelial cells, and many tumor cells. During organogenesis and tissue repair, HGF promotes epithelial/endothelial morphogenesis by inducing cell scattering and branching tubulogenesis. It also supports insulin production by pancreatic beta cells, neuronal survival, and immune tolerance. HGF is secreted as a propeptide that is activated by uPA or HGF Activator at sites of tissue damage. Its signaling through the receptor HGF R/c-MET is enhanced by its prior binding to heparan sulfate proteoglycans. The serum levels of HGF are elevated in a wide range of pathologies including liver damage, acute kidney failure, myocardial infarction, type 1 diabetes, obesity, and cancer, as well as in the synovial fluid of rheumatoid arthritis patients.

We have publications tested in 1 confirmed species: Human.

Showing Publications 1 - 10 of 29. Show All 29 Publications. Collapse Publications.

Publications using DY294	Applications	Species
Fattahi, P;de Hoyos-Vega, JM;Choi, JH;Duffy, CD;Gonzalez-Suarez, AM;Ishida, Y;Nguyen, KM;Gwon, K;Peterson, QP;Saito, T;Stybayeva, G;Revzin, A; Guiding Hepatic Differentiation of Pluripotent Stem Cells Using 3D Microfluidic Co-Cultures with Human Hepatocytes Cells 2023-08-01 [PMID: 37566061] (Human)		Human
Gwon, K;Choi, D;de Hoyos-Vega, JM;Baskaran, H;Gonzalez-Suarez, AM;Lee, S;Hong, HJ;Nguyen, KM;Dharmesh, E;Sugahara, G;Ishida, Y;Saito, T;Stybayeva, G;Revzin, A; Function of hepatocyte spheroids in bioactive microcapsules is enhanced by endogenous and exogenous hepatocyte growth factor Bioactive materials 2023-10-01 [PMID: 37266448] (Human)		Human
S Rutecki, P Szulc, M Paku?a, P Uruski, A Radziemski, E Naumowicz, R Moszy?ski, A Tykarski, J Miku?a-Pie, K Ksi??ek Pro-cancerogenic effects of spontaneous and drug-induced senescence of ovarian cancer cells in vitro and in vivo: a comparative analysis Journal of ovarian research, 2022-07-26;15(1):87. 2022-07-26 [PMID: 35883110] (Human)		Human
I Angelopoul, C Trigo, MI Ortuzar, J Cuenca, C Brizuela, M Khoury Delivery of affordable and scalable encapsulated allogenic/autologous mesenchymal stem cells in coagulated platelet poor plasma for dental pulp regeneration Scientific Reports, 2022-01-10;12(1):435. 2022-01-10 [PMID: 35013332] (Human)		Human
SJ Wang, R Li, TSC Ng, G Luthria, MJ Oudin, M Prytyskach, RH Kohler, R Weissleder, DA Lauffenbur, MA Miller Efficient blockade of locally reciprocated tumor-macrophage signaling using a TAM-avid nanotherapy Sci Adv, 2020-05-22;6(21):eaaz8521. 2020-05-22 [PMID: 32494745] (Human)		Human
JH Ko, HJ Kim, HJ Jeong, HJ Lee, JY Oh Mesenchymal Stem and Stromal Cells Harness Macrophage-Derived Amphiregulin to Maintain Tissue Homeostasis Cell Rep, 2020-03-17;30(11):3806-3820.e6. 2020-03-17 [PMID: 32187551] (Human)		Human
C Voisin, G Cauchois, L Reppel, C Laroye, L Louarn, C Schenowitz, P Sonon, I Poras, V Wang, E D Carosell, N Benkirane-, P Moreau, N Rouas-Frei, D Bensoussan, C Huselstein Are the Immune Properties of Mesenchymal Stem Cells from Wharton's Jelly Maintained during Chondrogenic Differentiation? J Clin Med, 2020-02-04;9(2):. 2020-02-04 [PMID: 32033151] (Human)		Human
M Paku?a, P Uruski, A Niklas, A Wo?niak, D Szpurek, A Tykarski, J Miku?a-Pie, K Ksi??ek A Unique Pattern of Mesothelial-Mesenchymal Transition Induced in the Normal Peritoneal Mesothelium by High-Grade Serous Ovarian Cancer Cancers (Basel), 2019-05-13;11(5):. 2019-05-13 [PMID: 31086083] (Human)		Human
K Shuto, M Mori, C Kosugi, K Narushima, S Nakabayash, T Fujisiro, A Sato, K Hayano, H Shimizu, K Koda Hepatic blood flow by perfusion computed tomography as an imaging biomarker for patients with gastric cancer Oncol Lett, 2019-01-25;17(3):3267-3276. 2019-01-25 [PMID: 30867759] (Human)		Human
MS Chen, TJ Wang, HC Lin, B Thierry Four types of human platelet lysate, including one virally inactivated by solvent-detergent, can be used to propagate Wharton Jelly mesenchymal stromal cells New biotechnology, 2018-11-20;0(0):. 2018-11-20 [PMID: 30465908] (Human)		Human
KA Correll, KE Edeen, EF Redente, RL Zemans, BL Edelman, T Danhorn, D Curran-Eve, A Mikels-Vig, RJ Mason TGF beta inhibits HGF, FGF7, and FGF10 expression in normal and IPF lung fibroblasts Physiol Rep, 2018-08-01;6(16):e13794. 2018-08-01 [PMID: 30155985] (Human)		Human
F Klatte-Sch, T Schmidt, M Uckert, S Scheffler, U Kalus, M Rojewski, H Schrezenme, A Pruss, B Wildemann Comparative Analysis of Different Platelet Lysates and Platelet Rich Preparations to Stimulate Tendon Cell Biology: An In Vitro Study Int J Mol Sci, 2018-01-10;19(1):. 2018-01-10 [PMID: 29320421] (Human)		Human
J Miku?a-Pie, P Uruski, S Szubert, K Maksin, R Moszy?ski, D Szpurek, A Wo?niak, S Sajdak, A Tykarski, K Ksi??ek The Proangiogenic Capabilities of Malignant Ascites Generated by Aggressive Ovarian Tumors Biomed Res Int, 2017-09-20;2017(0):2592496. 2017-09-20 [PMID: 29085834] (Human)		Human
J Ikari, AJ Nelson, J Obaid, A Giron-Mart, K Ikari, F Makino, S Iwasawa, Y Gunji, M Farid, X Wang, H Basma, D Demeo, C Feghali-Bo, O Holz, K Rabe, X Liu, SI Rennard Reduced microRNA-503 expression augments lung fibroblast VEGF production in chronic obstructive pulmonary disease PLoS ONE, 2017-09-07;12(9):e0184039. 2017-09-07 [PMID: 28880936] (Human)		Human
A Lampada, J O'Prey, G Szabadkai, KM Ryan, D Hochhauser, P Salomoni mTORC1-independent autophagy regulates receptor tyrosine kinase phosphorylation in colorectal cancer cells via an mTORC2-mediated mechanism Cell Death Differ., 2017-05-05;0(0):. 2017-05-05 [PMID: 28475179] (Human)		Human
YJ Chen, L Lankford, S Kabagambe, Z Saenz, P Kumar, D Farmer, A Wang Effect of 2-octylcyanoacrylate on placenta derived mesenchymal stromal cells on extracellular matrix Placenta, 2017-04-02;0(0):. 2017-04-02 [PMID: 28465002] (Human)		Human
Ewa Kontny Secretory activity of subcutaneous abdominal adipose tissue in male patients with rheumatoid arthritis and osteoarthritis - association with clinical and laboratory data Reumatologia, 2016-11-28;54(5):227-235. 2016-11-28 [PMID: 27994266] (Human)		Human
Hugh S O'Neill A Collagen Cardiac Patch Incorporating Alginate Microparticles Permits the Controlled Release of HGF and IGF-1 to Enhance Cardiac Stem Cell Migration and Proliferation J Tissue Eng Regen Med, 2017-06-19;0(0):. 2017-06-19 [PMID: 27943590]
Aubin K, Safoine M, Proulx M, Audet-Casgrain M, Côté J, Tetu F, Roy A, Fradette J Characterization of In Vitro Engineered Human Adipose Tissues: Relevant Adipokine Secretion and Impact of TNF-alpha. PLoS ONE, 2015-09-14;10(9):e0137612. 2015-09-14 [PMID: 26367137] (Human)		Human
Kim Aubin, Caroline Vincent, Maryse Proulx, Dominique Mayrand, Julie Fradette Creating capillary networks within human engineered tissues: Impact of adipocytes and their secretory products Acta Biomaterialia 2015-01-01 [PMID: 25278444] (Human)		Human
Frampton , John P, White , Joshua B, Simon , Arlyne B, Tsuei , Michael, Paczesny , Sophie, Takayama , Shuichi Aqueous two-phase system patterning of detection antibody solutions for cross-reaction-free multiplex ELISA. Sci Rep, 2014-05-02;4(0):4878. 2014-05-02 [PMID: 24786974] (Human)		Human
Shamis Y, Silva E, Hewitt K, Brudno Y, Levenberg S, Mooney D, Garlick J Fibroblasts derived from human pluripotent stem cells activate angiogenic responses in vitro and in vivo. PLoS ONE, 2013-12-30;8(12):e83755. 2013-12-30 [PMID: 24386271] (Human)		Human
Kim , Kwang S, Lee , Hong J, An , Jin, Kim , Yun B, Ra , Jung Cha, Lim , Inja, Kim , Seung U Transplantation of human adipose tissue-derived stem cells delays clinical onset and prolongs life span in ALS mouse model. Cell Transplant, 2013-09-18;23(12):1585-97. 2013-09-18 [PMID: 24070071] (Human)		Human
Ramani VC, Yang Y, Ren Y Heparanase Plays a Dual Role in Driving Hepatocyte Growth Factor (HGF) Signaling by Enhancing HGF Expression and Activity. J. Biol. Chem., 2010-12-03;286(8):6490-9. 2010-12-03 [PMID: 21131364] (Human)		Human
Boneberg EM, Legler DF, Hoefer MM, Ohlschlegel C, Steininger H, Fuzesi L, Beer GM, Dupont-Lampert V, Otto F, Senn HJ, Furstenberger G Angiogenesis and lymphangiogenesis are downregulated in primary breast cancer. Br. J. Cancer, 2009-08-18;101(4):605-14. 2009-08-18 [PMID: 19672262] (Human)		Human
Quesnel C, Marchand-Adam S, Fabre A, Marchal-Somme J, Philip I, Lasocki S, Lecon V, Crestani B, Dehoux M Regulation of hepatocyte growth factor secretion by fibroblasts in patients with acute lung injury. Am. J. Physiol. Lung Cell Mol. Physiol., 2007-12-07;294(2):L334-43. 2007-12-07 [PMID: 18065658] (Human)		Human
Aydin S, Signorelli S, Lechleitner T, Joannidis M, Pleban C, Perco P, Pfaller W, Jennings P Influence of microvascular endothelial cells on transcriptional regulation of proximal tubular epithelial cells. Am. J. Physiol., Cell Physiol., 2007-12-05;294(2):C543-54. 2007-12-05 [PMID: 18057119] (Human)		Human
Skibinski G, Elborn JS, Ennis M Bronchial epithelial cell growth regulation in fibroblast cocultures: the role of hepatocyte growth factor. Am. J. Physiol. Lung Cell Mol. Physiol., 2007-03-23;293(1):L69-76. 2007-03-23 [PMID: 17384084] (Human)		Human
Gherardi E, Sandin S, Petoukhov MV, Finch J, Youles ME, Ofverstedt LG, Miguel RN, Blundell TL, Vande Woude GF, Skoglund U, Svergun DI Structural basis of hepatocyte growth factor/scatter factor and MET signalling. Proc. Natl. Acad. Sci. U.S.A., 2006-03-06;103(11):4046-51. 2006-03-06 [PMID: 16537482] (Human)		Human
Show All 29 Publications. Collapse Publications.

Array DY294

• HGF Antibodies
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• HGF Lysate
• HGF Proteins
• HGF ELISAs
• HGF Proteins and Enzymes