Name: Histone H2AX Antibody (322105)
Brand: Novus Biologicals
SKU: MAB3406
Price: 419 USD

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Reactivity	Hu, Mu, RtSpecies Glossary
Applications	WB, ICC/IF
Clone	322105
Clonality	Monoclonal
Host	Mouse
Conjugate	Unconjugated
Concentration	LYOPH

Immunogen	E. coli-derived recombinant human Histone H2AX Gly3-Ser131 Accession # P16104
Specificity	Detects human, mouse and rat Histone H2AX in Western blots.
Source	N/A
Isotype	IgG2a
Clonality	Monoclonal
Host	Mouse
Gene	H2AFX
Purity Statement	Protein A or G purified from hybridoma culture supernatant
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer	Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative	No Preservative
Concentration	LYOPH
Reconstitution Instructions	Reconstitute at 0.5 mg/mL in sterile PBS.

Publications using MAB3406	Applications	Species
Lima, C;Andrade-Barros, AI;Carvalho, FF;Falc�o, MAP;Lopes-Ferreira, M; Inflammasome Coordinates Senescent Chronic Wound Induced by Thalassophryne nattereri Venom International journal of molecular sciences 2023-05-08 [PMID: 37176162] (IHC, Mouse)	IHC	Mouse
Takuto Nishida, Isao Naguro, Hidenori Ichijo NAMPT-dependent NAD+ salvage is crucial for the decision between apoptotic and necrotic cell death under oxidative stress Cell Death Discovery 2022-04-11 [PMID: 35410407]
A Schepsky, G Asta Traus, J Petur Joel, S Ingthorsso, J Kricker, J Thor Bergt, A Asbjarnars, T Gudjonsson, N Nupponen, A Slipicevic, F Lehmann, T Gudjonsson Melflufen, a peptide-conjugated alkylator, is an efficient anti-neo-plastic drug in breast cancer cell lines Cancer Med, 2020-07-27;0(0):. 2020-07-27 [PMID: 32717133] (Western Blot, Human)	Western Blot	Human
CJ Bakkenist, RK Czambel, Y Lin, NA Yates, X Zeng, J Shogan, JC Schmitz Quantitative analysis of ATM phosphorylation in lymphocytes DNA Repair (Amst.), 2019-06-04;80(0):1-7. 2019-06-04 [PMID: 31176958] (IR Fluorescence, Human)	IR Fluorescence	Human
M Minata, A Audia, J Shi, S Lu, J Bernstock, MS Pavlyukov, A Das, SH Kim, YJ Shin, Y Lee, H Koo, K Snigdha, I Waghmare, X Guo, A Mohyeldin, D Gallego-Pe, J Wang, D Chen, P Cheng, F Mukheef, M Contreras, JF Reyes, B Vaillant, EP Sulman, SY Cheng, JM Markert, BA Tannous, X Lu, M Kango-Sing, LJ Lee, DH Nam, I Nakano, KP Bhat Phenotypic Plasticity of Invasive Edge Glioma Stem-like Cells in Response to Ionizing Radiation Cell Rep, 2019-02-12;26(7):1893-1905.e7. 2019-02-12 [PMID: 30759398] (ICC, Human)	ICC	Human
S Wichaiyo, S Lax, SJ Montague, Z Li, B Grygielska, JA Pike, EJ Haining, A Brill, SP Watson, J Rayes Platelet glycoprotein VI and C-type lectin-like receptor 2 deficiency accelerates wound healing by impairing vascular integrity in mice Haematologica, 2019-02-07;0(0):. 2019-02-07 [PMID: 30733265] (IHC-P, Mouse)	IHC-P	Mouse
JH Jeong, Y Cheol Kang, Y Piao, S Kang, YK Pak miR-24-mediated knockdown of H2AX damages mitochondria and the insulin signaling pathway Exp. Mol. Med., 2017-04-07;49(4):e313. 2017-04-07 [PMID: 28386126] (Western Blot, Human)	Western Blot	Human
Zhongshuang Hu, Taisuke Murakami, Hiroshi Tamura, Johannes Reich, Kyoko Kuwahara-Arai, Toshiaki Iba et al. Neutrophil extracellular traps induce IL-1 beta production by macrophages in combination with lipopolysaccharide International Journal of Molecular Medicine 2017-03-01 [PMID: 28204821]
Prevete N, Liotti F, Visciano C, Marone G, Melillo R, de Paulis A The formyl peptide receptor 1 exerts a tumor suppressor function in human gastric cancer by inhibiting angiogenesis. Oncogene, 2014-09-29;34(29):3826-38. 2014-09-29 [PMID: 25263443] (IHC-Fr, Mouse)	IHC-Fr	Mouse

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Catalog# & Formulation	Size	Price
Carrier Free MAB3406-SP

Gene Symbol	H2AFX
Uniprot	P16104()