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Helios Antibody (22F6) [DyLight 650]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
22F6
Clonality
Monoclonal
Host
Armenian Hamster
Conjugate
DyLight 650

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-37723AF350
Alexa Fluor 405
NBP2-37723AF405
Alexa Fluor 488
NBP2-37723AF488
Alexa Fluor 532
NBP2-37723AF532
Alexa Fluor 594
NBP2-37723AF594
Alexa Fluor 647
NBP2-37723AF647
Alexa Fluor 700
NBP2-37723AF700
Alexa Fluor 750
NBP2-37723AF750
Allophycocyanin
NBP2-37723APC
DyLight 350
NBP2-37723UV
DyLight 405
NBP2-37723V
DyLight 488
NBP2-37723G
DyLight 550
NBP2-37723R
DyLight 594
NBP2-37723DL594
DyLight 680
NBP2-37723FR
DyLight 755
NBP2-37723IR
FITC
NBP2-37723F
Janelia Fluor 549
NBP2-37723JF549
Janelia Fluor 646
NBP2-37723JF646
PE
NBP2-37723PE
PerCP
NBP2-37723PCP
Unconjugated
NBP2-37723
mFluor Violet 450 SE
NBP2-37723MFV450
mFluor Violet 500 SE
NBP2-37723MFV500
mFluor Violet 610 SE
NBP2-37723MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-37723
BSA Free
NBP2-37723
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Helios Antibody (22F6) [DyLight 650] Summary

Immunogen
Peptide coresponding to the amino acids 51-107 of Helios.
Specificity
The armenian hamster monoclonal antibody 22F6 recognizes Helios, a transcription factor expressed in some hematopoietic stem cells, and at high levels in thymic-derived regulatory T cells.
Isotype
IgG
Clonality
Monoclonal
Host
Armenian Hamster
Gene
IKZF2
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Helios Antibody (22F6) [DyLight 650]

  • Helios
  • IKAROS family zinc finger 2 (Helios)
  • Ikaros family zinc finger protein 2
  • IKZF2
  • MGC34330
  • subfamily 1A, 2 (Helios)
  • zinc finger DNA binding protein Helios
  • zinc finger protein Helios
  • ZNF1A2
  • ZNFN1A2

Background

HELIOS encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This protein forms homo- or hetero-dimers with other Ikaros family members, and is thought to function predominantly in early hematopoietic development. Multiple transcript variants encoding different isoforms have been found for this gene, but the biological validity of some variants has not been determined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol IKZF2