HCLS1 Antibody Summary
Immunogen |
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human HCLS1. The exact sequence is proprietary. |
Localization |
Membrane, Peripheral membrane protein (Probable) , Cytoplasm (Probable) , Mitochondrion |
Predicted Species |
Rat (100%), Chicken (92%), Monkey (100%), Bovine (93%). Backed by our 100% Guarantee. |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Rabbit |
Gene |
HCLS1 |
Purity |
Antigen Affinity-purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunohistochemistry 10 - 1:500
- Immunohistochemistry-Paraffin 1:100-1:1000
- Western Blot 1:5000-1:20000
|
Reactivity Notes
Immunogen displays the following percentage of sequence identity for non-tested species: Rhesus Monkey (100%).
Packaging, Storage & Formulations
Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Buffer |
PBS (pH 7), 20% Glycerol |
Preservative |
0.01% Thimerosal |
Purity |
Antigen Affinity-purified |
Alternate Names for HCLS1 Antibody
Background
Hematopoietic cell specific Lyn substrate 1 (HCLS1) is an intracellular protein involved in the signal transduction pathways in B and T lymphocytes. HCLS1 Tyr phosphorylation catalyzed by Syk and Lyn plays a crucial role in the translocation of the protein to the membrane and is involved in the cytoskeleton rearrangement triggered by thrombin in human platelets. The gene is a substrate for caspase cleavage during apoptosis.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information go to www.P65Warnings.ca.gov.
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Secondary Antibodies
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