Glut4 Antibody [Alexa Fluor® 647]

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

The stimulation of glucose uptake by insulin in muscle and adipose tissue requires translocation of the GLUT4 glucose transporter from intracellular storage sites to the cell surface. Activation of phosphatidylinositol-3-OH kinase (PI3K) is required for this trafficking event, but it is not sufficient to produce GLUT4 translocation. Human insulin resistance involves a defect in GLUT4 traffic and targeting leading to accumulation in a dense membrane compartment from which insulin is unable to recruit GLUT4 to the cell surface.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: FLOW.

Showing Publications 1 - 2 of 2.

Publications using NBP1-49533AF647	Applications	Species
Abusarah J, Khodayarian F, El-Hachem N Et al. Engineering immunoproteasome-expressing mesenchymal stromal cells: A potent cellular vaccine for lymphoma and melanoma in mice Cell Rep Med 2022-01-14 [PMID: 35028603] (FLOW) Details: Citation using the Alexa Fluor 647 version of this antibody.	FLOW
Prado-Garcia H, Campa-Higareda A, Romero-Garcia S Lactic Acidosis in the Presence of Glucose Diminishes Warburg Effect in Lung Adenocarcinoma Cells Front Oncol 2020-06-12 [PMID: 32596143] (FLOW, Human) Details: Citation using the Alexa Fluor 647 format of this antibody.	FLOW	Human

Images	Ratings	Applications	Species	Date	Details
	4 reviewed by: Anja Kusch	Flow	Mouse	01/26/2023	View Summary Application Flow Cytometry Sample Tested Thymus tissue Species Mouse Lot G-010421-AF647 Comments Comments Use on Thymic Epithelial cells. In comparison to the negative and IgG control the Glut4 staining showed a clear staining. The fluorescence intensity could be higher though.
Enlarge	4 reviewed by: Verified Customer	Flow	Mouse	02/26/2015	View Summary Application Flow Cytometry Sample Tested Murine/Mouse's CD4+ T cells Species Mouse Lot A-5-AF647

Array NBP1-49533AF647

• Glut4 Antibodies
• Glut4 ELISA Kits
• Glut4 Lysate
• Glut4 Protein