Name: Glut1 Antibody (202915) [Unconjugated]
Brand: Novus Biologicals
SKU: MAB1418
Price: 459 USD

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Reactivity	HuSpecies Glossary
Applications	Flow, CyTOF-ready, ICC/IF
Clone	202915
Clonality	Monoclonal
Host	Mouse
Conjugate	Unconjugated

Catalog# & Conjugate	Size	Price
Alexa Fluor 350 FAB1418U-100UG

Alexa Fluor 405 FAB1418V-100UG

Alexa Fluor 488 FAB1418G-100UG

Alexa Fluor 532 FAB1418X

Alexa Fluor 594 FAB1418T-100UG

Alexa Fluor 700 FAB1418N

Alexa Fluor 750 FAB1418S-100UG

Allophycocyanin FAB1418A

Allophycocyanin/Cy7 FAB1418APCCY7

Biotin FAB1418B

DyLight 350 FAB1418D

DyLight 405 FAB1418E

DyLight 488 FAB1418K

DyLight 550 FAB1418L

DyLight 594 FAB1418M

DyLight 650 FAB1418W

DyLight 680 FAB1418Y

DyLight 755 FAB1418Z

Fluorescein FAB1418F

HRP FAB1418H

Janelia Fluor 525 FAB1418JF525

Janelia Fluor 549 FAB1418I

Janelia Fluor 585 FAB1418JF585

Janelia Fluor 635 FAB1418JF635

Janelia Fluor 646 FAB1418J

Janelia Fluor 669 FAB1418JF669

PE/Atto594 FAB1418PEATT594

PE/Cy5.5 FAB1418PECY55

PE/Cy7 FAB1418PECY7

Phycoerythrin FAB1418P

Catalog# & Formulation	Size	Price
Carrier Free FAB1418A

Carrier Free FAB1418N

Carrier Free FAB1418F

Carrier Free FAB1418P

Carrier Free MAB1418-SP

Carrier Free FAB1418V-100UG

Carrier Free FAB1418U-100UG

Carrier Free FAB1418T-100UG

Carrier Free FAB1418S-100UG

Carrier Free FAB1418G-100UG

Conjugate	Catalog #	Availability	Size	Price
Alexa Fluor 350	FAB1418U-100UG
Alexa Fluor 405	FAB1418V-100UG
Alexa Fluor 488	FAB1418G-100UG
Alexa Fluor 532	FAB1418X
Alexa Fluor 594	FAB1418T-100UG
Alexa Fluor 700	FAB1418N
Alexa Fluor 750	FAB1418S-100UG
Allophycocyanin	FAB1418A
Allophycocyanin/Cy7	FAB1418APCCY7
Biotin	FAB1418B
DyLight 350	FAB1418D
DyLight 405	FAB1418E
DyLight 488	FAB1418K
DyLight 550	FAB1418L
DyLight 594	FAB1418M
DyLight 650	FAB1418W
DyLight 680	FAB1418Y
DyLight 755	FAB1418Z
Fluorescein	FAB1418F
HRP	FAB1418H
Janelia Fluor 525	FAB1418JF525
Janelia Fluor 549	FAB1418I
Janelia Fluor 585	FAB1418JF585
Janelia Fluor 635	FAB1418JF635
Janelia Fluor 646	FAB1418J
Janelia Fluor 669	FAB1418JF669
PE/Atto594	FAB1418PEATT594
PE/Cy5.5	FAB1418PECY55
PE/Cy7	FAB1418PECY7
Phycoerythrin	FAB1418P

Glut1 Antibody (202915) [Unconjugated]

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Glut1 Antibody (202915) [Unconjugated] Summary

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Publications for Glut1 Antibody (MAB1418)(27)

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Bioinformatics

Immunogen	NS0 mouse myeloma cell line transfected with human Glut1 Met1-Val492 Accession # AAA52571
Specificity	Detects human Glut1. Stains human Glut1-transfected NS0 cells, but not NS0 control transfectants. Although Human Glut1 Antibody detects Glut1 on the surface of T cells (1, 2), it does not detect it on erythrocytes (5). The reason for this discrepancy is not understood, but may be related to conformational or post-translational modification differences.
Source	N/A
Isotype	IgG2b
Clonality	Monoclonal
Host	Mouse
Gene	SLC2A1
Purity Statement	Protein A or G purified from hybridoma culture supernatant
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer	Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative	No Preservative
Reconstitution Instructions	Reconstitute at 0.5 mg/mL in sterile PBS.

Publications using MAB1418	Applications	Species
H Cho, HY Kwon, A Sharma, SH Lee, X Liu, N Miyamoto, JJ Kim, SH Im, NY Kang, YT Chang Visualizing inflammation with an M1 macrophage selective probe via GLUT1 as the gating target Nature Communications, 2022-10-10;13(1):5974. 2022-10-10 [PMID: 36216803] (Flow Cytometry, Human)	Flow Cytometry	Human
McTernan PM, Levitt DE, Welsh DA et al. Alcohol Impairs Immunometabolism and Promotes Na�ve T Cell Differentiation to Pro-Inflammatory Th1 CD4(+) T Cells Frontiers in Immunology 2022-05-12 [PMID: 35634279]
McTernan PM, Levitt DE, Welsh DA et al. Alcohol Impairs Immunometabolism and Promotes Na�ve T Cell Differentiation to Pro-Inflammatory Th1 CD4(+) T Cells Frontiers in Immunology 5/12/2022 [PMID: 35634279]
Juan Carlos Montero, Elisa Calvo-Jiménez, Sofía del Carmen, Mar Abad, Alberto Ocaña, Atanasio Pandiella Surfaceome analyses uncover CD98hc as an antibody drug-conjugate target in triple negative breast cancer Journal of Experimental & Clinical Cancer Research 12/1/2022 [PMID: 35317825]
Patrícia Neuperger, József Á. Balog, László Tiszlavicz, József Furák, Nikolett Gémes, Edit Kotogány et al. Analysis of the Single-Cell Heterogeneity of Adenocarcinoma Cell Lines and the Investigation of Intratumor Heterogeneity Reveals the Expression of Transmembrane Protein 45A (TMEM45A) in Lung Adenocarcinoma Cancer Patients Cancers (Basel) 12/29/2021 [PMID: 35008313]
Samantha M. Morrissey, Fan Zhang, Chuanlin Ding, Diego Elias Montoya-Durango, Xiaoling Hu, Chenghui Yang et al. Tumor-derived exosomes drive immunosuppressive macrophages in a pre-metastatic niche through glycolytic dominant metabolic reprogramming Cell Metabolism 10/1/2021 [PMID: 34559989]
Lan Huang, Joyce Bischoff Isolation of Stem Cells, Endothelial Cells and Pericytes from Human Infantile Hemangioma BIO-PROTOCOL 1/20/2020 [PMID: 33654720]
R Alföldi, JÁ Balog, N Faragó, M Halmai, E Kotogány, P Neuperger, LI Nagy, LZ Fehér, GJ Szebeni, LG Puskás Single Cell Mass Cytometry of Non-Small Cell Lung Cancer Cells Reveals Complexity of In vivo And Three-Dimensional Models over the Petri-dish Cells, 2019-09-16;8(9):. 2019-09-16 [PMID: 31527554] (Flow Cytometry, Human)	Flow Cytometry	Human
Thilipan Thaventhiran, Wai Wong, Ahmad F. Alghanem, Naif Alhumeed, Mohammad A. Aljasir, Simeon Ramsey et al. CD28 Superagonistic Activation of T Cells Induces a Tumor Cell-Like Metabolic Program Monoclonal Antibodies in Immunodiagnosis and Immunotherapy 4/23/2019 [PMID: 31009338]
G Duette, P Pereyra Ge, J Rubione, PS Perez, AL Landay, SM Crowe, Z Liao, KW Witwer, MP Holgado, J Salido, J Geffner, O Sued, CS Palmer, M Ostrowski Induction of HIF-1? by HIV-1 Infection in CD4+ T Cells Promotes Viral Replication and Drives Extracellular Vesicle-Mediated Inflammation MBio, 2018-09-11;9(5):. 9/11/2018 [PMID: 30206166]
GA Gualdoni, KA Mayer, AM Kapsch, K Kreuzberg, A Puck, P Kienzl, F Oberndorfe, K Frühwirth, S Winkler, D Blaas, GJ Zlabinger, J Stöckl Rhinovirus induces an anabolic reprogramming in host cell metabolism essential for viral replication Proc. Natl. Acad. Sci. U.S.A., 2018-07-09;115(30):E7158-E7165. 2018-07-09 [PMID: 29987044] (Flow Cytometry, Human)	Flow Cytometry	Human
Jesse J. R. Masson, Catherine L. Cherry, Nicholas M. Murphy, Isabel Sada-Ovalle, Tabinda Hussain, Riya Palchaudhuri et al. Polymorphism rs1385129 Within Glut1 Gene SLC2A1 Is Linked to Poor CD4+ T Cell Recovery in Antiretroviral-Treated HIV+ Individuals Frontiers in Immunology 5/17/2018 [PMID: 29867928]
D Vignali, E Cantarelli, C Bordignon, A Canu, A Citro, A Annoni, L Piemonti, P Monti Detection and Characterization of CD8+ Autoreactive Memory Stem T Cells in Patients with Type 1 Diabetes Diabetes, 2018-03-05;0(0):. 2018-03-05 [PMID: 29506985] (IHC, Human)	IHC	Human
Clovis S. Palmer, Gabriel A. Duette, Marc C. E. Wagner, Darren C. Henstridge, Suah Saleh, Candida Pereira et al. Metabolically active CD4+ T cells expressing Glut1 and OX40 preferentially harbor HIV during in vitro infection FEBS Letters 10/11/2017 [PMID: 28892135]
JJR Masson, AJ Murphy, MKS Lee, M Ostrowski, SM Crowe, CS Palmer Assessment of metabolic and mitochondrial dynamics in CD4+ and CD8+ T cells in virologically suppressed HIV-positive individuals on combination antiretroviral therapy PLoS ONE, 2017-08-30;12(8):e0183931. 8/30/2017 [PMID: 28854263]
SK Varanasi, D Donohoe, U Jaggi, BT Rouse Manipulating Glucose Metabolism during Different Stages of Viral Pathogenesis Can Have either Detrimental or Beneficial Effects J. Immunol., 2017-08-02;0(0):. 2017-08-02 [PMID: 28768727] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
HL Yeoh, AC Cheng, CL Cherry, JM Weir, PJ Meikle, JF Hoy, SM Crowe, CS Palmer Immunometabolic and Lipidomic Markers Associated With the Frailty Index and Quality of Life in Aging HIV+ Men on Antiretroviral Therapy EBioMedicine, 2017-07-18;0(0):. 7/18/2017 [PMID: 28754302]
Kathy A. Clow, Connie E. Short, Jennifer R. Hall, Robert L. Gendron, Hélène Paradis, Ankur Ralhan et al. High rates of glucose utilization in the gas gland of Atlantic cod (Gadus morhua) are supported by GLUT1 and HK1b Journal of Experimental Biology 4/11/2016 [PMID: 27401755]
Clovis S. Palmer, Catherine L. Cherry, Isabel Sada-Ovalle, Amit Singh, Suzanne M. Crowe Glucose Metabolism in T Cells and Monocytes: New Perspectives in HIV Pathogenesis EBioMedicine 4/1/2016 [PMID: 27211546]
Emerging Role and Characterization of Immunometabolism: Relevance to HIV Pathogenesis, Serious Non-AIDS Events, and a Cure J Immunol, 2016-06-01;196(11):4437-44. 2016-06-01 [PMID: 27207806] (Flow Cytometry, Human)	Flow Cytometry	Human
Basu S, Hubbard B, Shevach E Foxp3-mediated inhibition of Akt inhibits Glut1 (glucose transporter 1) expression in human T regulatory cells. J Leukoc Biol, 2014-12-09;97(2):279-83. 2014-12-09 [PMID: 25492937] (Flow Cytometry, Human)	Flow Cytometry	Human
Palmer C, Ostrowski M, Gouillou M, Tsai L, Yu D, Zhou J, Henstridge D, Maisa A, Hearps A, Lewin S, Landay A, Jaworowski A, McCune J, Crowe S Increased glucose metabolic activity is associated with CD4+ T-cell activation and depletion during chronic HIV infection. AIDS, 2014-01-28;28(3):297-309. 2014-01-28 [PMID: 24335483] (Flow Cytometry, Human)	Flow Cytometry	Human
Chan O, Burke J, Gao D, Fish E The chemokine CCL5 regulates glucose uptake and AMP kinase signaling in activated T cells to facilitate chemotaxis. J Biol Chem, 2012-07-10;287(35):29406-16. 2012-07-10 [PMID: 22782897] (Flow Cytometry, Human)	Flow Cytometry	Human
Tanaka A, Jinno-Oue A, Shimizu N Entry of human T-cell leukemia virus type 1 is augmented by heparin sulfate proteoglycans bearing short heparin-like structures. J. Virol., 2012-01-11;86(6):2959-69. 2012-01-11 [PMID: 22238310] (Flow Cytometry, Human)	Flow Cytometry	Human
Han M, Lee H, Cho K, Kim J, Roh J, Choi S, Nam S, Kim S Role of FDG-PET as a biological marker for predicting the hypoxic status of tongue cancer. Head Neck, 2011-11-03;34(10):1395-402. 2011-11-03 [PMID: 22052623] (IHC, Human)	IHC	Human
Jain P, Manuel SL, Khan ZK, Ahuja J, Quann K, Wigdahl B DC-SIGN mediates cell-free infection and transmission of human T-cell lymphotropic virus type 1 by dendritic cells. J. Virol., 2009-08-19;83(21):10908-21. 2009-08-19 [PMID: 19692463] (Flow Cytometry, Human)	Flow Cytometry	Human
Luty WH, Rodeberg D, Parness J, Vyas YM Antiparallel segregation of notch components in the immunological synapse directs reciprocal signaling in allogeneic Th:DC conjugates. J. Immunol., 2007-07-15;179(2):819-29. 2007-07-15 [PMID: 17617572] (ICC, Human)	ICC	Human
Show All 27 Publications. Collapse Publications.

Gene Symbol	SLC2A1
Uniprot	AAA52571()