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GLS2 Antibody (CL7716)

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Immunohistochemistry-Paraffin: GLS2 Antibody (CL7716) [NBP2-88907] - Analysis in human liver and skeletal muscle tissues using NBP2-88907 antibody. Corresponding GLS2 RNA-seq data are presented for the same tissues.
Orthogonal Strategies: Immunohistochemistry-Paraffin: GLS2 Antibody (CL7716) [NBP2-88907] - Analysis in human liver and skeletal muscle tissues using NBP2-88907 antibody. Corresponding GLS2 RNA-seq data are ...read more
Immunohistochemistry-Paraffin: GLS2 Antibody (CL7716) [NBP2-88907] - Staining of human skeletal muscle shows no positivity in myocytes as expected.
Immunohistochemistry-Paraffin: GLS2 Antibody (CL7716) [NBP2-88907] - Staining of human liver shows strong granular cytoplasmic positivity in hepatocytes.
Immunohistochemistry-Paraffin: GLS2 Antibody (CL7716) [NBP2-88907] - Staining of human pancreas shows moderate granular cytoplasmic positivity in exocrine glandular cells.
Immunohistochemistry-Paraffin: GLS2 Antibody (CL7716) [NBP2-88907] - Staining of human prostate shows no positivity in glandular cells as expected.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clone
CL7716
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

  

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GLS2 Antibody (CL7716) Summary

Immunogen
This antibody was developed against a synthetic peptide corresponding to amino acids: GRETPHSHQPQHQDHDSSE
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
GLS2
Purity
Protein A purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:500 - 1:1000
  • Immunohistochemistry-Paraffin 1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Reactivity Notes

Mouse, Rat (83%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, pH 7.2, containing 40% glycerol
Preservative
0.02% Sodium Azide
Purity
Protein A purified

Alternate Names for GLS2 Antibody (CL7716)

  • EC 3.5.1.2
  • GAbreast cell glutaminase
  • GLSglutaminase GA
  • glutaminase 2 (liver, mitochondrial)
  • glutaminase I
  • glutaminase liver isoform, mitochondrial
  • hLGA
  • LGA
  • L-glutaminase
  • L-glutamine amidohydrolase
  • MGC71567
  • phosphate-activated glutaminase
  • phosphate-dependent glutaminase
  • truncated glutaminase 2

Background

The protein encoded by the GLS2 gene is a mitochondrial phosphate-activated glutaminase that catalyzes the hydrolysis of glutamine to stoichiometric amounts of glutamate and ammonia. This protein is functionally similar to the kidney glutaminase but is a little smaller in size. Originally thought to be liver-specific, this protein has been found in other tissues as well. At least one transcribed pseudogene has been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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GLS2 Antibody
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NBP2-88907
GLS2 Antibody (CL7716)
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Applications: IHC

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Bioinformatics

Gene Symbol GLS2