Home » GCH1 » GCH1 Antibodies » GCH1 Antibody

GCH1 Antibody

 Submit a Review

Images

 
(
Enlarge)
Immunohistochemistry-Paraffin: GCH1 Antibody [NBP3-12307] - Mouse spleen. 1:100 dilution in IHC blocking buffer. DAB (brown) staining and Hematoxylin QS (blue) counterstain. 40X magnfication.
Immunohistochemistry-Paraffin: GCH1 Antibody [NBP3-12307] - Mouse spleen. 1:100 dilution in IHC blocking buffer. DAB (brown) staining and Hematoxylin QS (blue) counterstain. 40X magnfication.
Immunohistochemistry-Paraffin: GCH1 Antibody [NBP3-12307] - Mouse spleen. 1:100 dilution in IHC blocking buffer. DAB (brown) staining and Hematoxylin QS (blue) counterstain. 10X magnfication.

Product Details

Summary
Reactivity Mu, RtSpecies Glossary
Applications WB, ELISA, IHC, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Novus Biologicals offers 100% Guarantee

GCH1 Antibody Summary

Immunogen
Synthetic peptide taken within amino acid region 25-75 on mouse GTPCHI protein.
Clonality
Polyclonal
Host
Rabbit
Gene
GCH1
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • ELISA 1:20000
  • Immunohistochemistry 1:100
  • Immunohistochemistry-Paraffin 1:100
  • Immunoprecipitation 1:200
  • Western Blot 1:500-1:750

Packaging, Storage & Formulations

Storage
Store at 4C short term. Store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Contains Tris, HCl/glycine buffer (pH 7.4-7.8), 30% glycerol, 0.5% BSA, along with cryo-protective agents, and HEPES (exact storage and stabilization buffer information is proprietary).
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for GCH1 Antibody

  • dystonia 14
  • DYT14
  • DYT5
  • DYT5a
  • DYT5EC 3.5.4.16
  • GCH
  • GCH1
  • GTP cyclohydrolase 1
  • GTP cyclohydrolase I
  • GTPCH1
  • GTP-CH-1
  • GTP-CH-I
  • guanosine 5'-triphosphate cyclohydrolase I
  • HPABH4B

Background

GCH1 encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described; however, not all variants give rise to a functional enzyme.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

Tyrosine
Hydroxylase Antibody
NB300-109
Immunohistochemistry-Frozen Tyrosine Hydroxylase Antibody
Immunohistochemistry Tyrosine Hydroxylase Antibody
Immunohistochemistry Tyrosine Hydroxylase Antibody
(7 Reviews)
(240 Publications)
Species: Ch, Dr, Hu, I, Ma, Mu, Rt
Applications: Dual ISH-IHC, ICC/IF, IHC-FrFl, IHC-WhMt, IHC, IHC-Fr, IHC-P, KO, Simple Western, WB
iNOS Antibody -
BSA Free
NB300-605
Western Blot iNOS Antibody - BSA Free
Western Blot iNOS Antibody - BSA Free
Western Blot iNOS Antibody - BSA Free
(3 Reviews)
(141 Publications)
Species: Hu, Mu, Po, Rt
Applications: Flow, IB, ICC/IF, IHC, IHC-Fr, IHC-P, In vitro, WB
eNOS Antibody -
BSA Free
NB300-500
Western Blot eNOS Antibody - BSA Free
Immunohistochemistry-Paraffin eNOS Antibody - BSA Free
Immunohistochemistry-Paraffin eNOS Antibody - BSA Free
(3 Reviews)
(29 Publications)
Species: Am, Bv, Ca, Dr, Hu, Mu, Po, Rt, Sh
Applications: IHC, IHC-Fr, IHC-P, WB
nNOS Antibody
NB100-858
Immunocytochemistry/ Immunofluorescence nNOS Antibody
Flow Cytometry nNOS Antibody
Immunocytochemistry/ Immunofluorescence nNOS Antibody
(1 Review)
(15 Publications)
Species: Gp, Hu, Mu, Rt
Applications: Flow, ICC/IF, IHC-WhMt, IHC, IHC-Fr, IHC-P, PEP-ELISA, WB
SPR Antibody
(OTI4F5)
NBP2-03256
Flow Cytometry SPR Antibody (OTI4F5)
Flow Cytometry SPR Antibody (OTI4F5)
Western Blot SPR Antibody (OTI4F5)
Species: Hu, Rt
Applications: Flow, ICC/IF, IHC, IHC-P, WB
TNF-alpha
[Unconjugated]
210-TA
SDS-PAGE TNF-alpha [Unconjugated]
Bioactivity TNF-alpha [Unconjugated]
SEC-MALS TNF-alpha [Unconjugated]
(3 Reviews)
(822 Publications)
Species: Hu
Applications: BA
Torsin A Antibody
- BSA Free
NBP3-03780
Immunohistochemistry-Paraffin Torsin A Antibody - BSA Free
Immunohistochemistry-Paraffin Torsin A Antibody - BSA Free
Western Blot Torsin A Antibody - BSA Free
Species: Hu, Mu, Rt
Applications: IHC, IHC-P, WB
ISYNA1 Antibody
NBP2-47415
Immunocytochemistry/ Immunofluorescence ISYNA1 Antibody
Immunohistochemistry-Paraffin ISYNA1 Antibody
Immunohistochemistry-Paraffin ISYNA1 Antibody
Species: Hu
Applications: ICC/IF, IHC, IHC-P, WB
PTS Antibody
NBP1-32975
Western Blot PTS Antibody
Western Blot PTS Antibody
Immunocytochemistry/ Immunofluorescence PTS Antibody
Species: Hu, Mu
Applications: ICC/IF, IHC, IHC-P, KO, WB
HPD Antibody
NBP1-89366
Western Blot HPD Antibody
Western Blot HPD Antibody
Immunohistochemistry-Paraffin HPD Antibody
Species: Hu, Mu, Rt
Applications: IHC, IHC-P, WB
Phenylalanine
Hydroxylase Antibody
NBP2-48615
Immunohistochemistry-Paraffin Phenylalanine Hydroxylase Antibody
Immunohistochemistry-Paraffin Phenylalanine Hydroxylase Antibody
Immunohistochemistry-Paraffin Phenylalanine Hydroxylase Antibody
(1 Publication)
Species: Hu
Applications: IHC, IHC-P, WB
Glut1 Antibody -
BSA Free
NB110-39113
Western Blot Glut1 Antibody - BSA Free
Flow Cytometry Glut1 Antibody - BSA Free
Western Blot Glut1 Antibody - BSA Free
(7 Reviews)
(69 Publications)
Species: Hu, Mu, Rb, Rt
Applications: ChIP, ChIP, Flow-IC, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, In vitro, Simple Western, WB
Nanos2 Antibody -
BSA Free
NBP1-76917
Immunocytochemistry/ Immunofluorescence Nanos2 Antibody - BSA Free
Western Blot Nanos2 Antibody - BSA Free
Immunohistochemistry-Paraffin Nanos2 Antibody - BSA Free
Species: Hu, Mu, Rt
Applications: ELISA, ICC/IF, IHC, IHC-P, WB
Dopa
Decarboxylase/DDC Ant ...
AF3564
Western Blot Dopa Decarboxylase/DDC Antibody [Unconjugated]
Immunohistochemistry Dopa Decarboxylase/DDC Antibody [Unconjugated]
Immunohistochemistry Dopa Decarboxylase/DDC Antibody [Unconjugated]
(4 Publications)
Species: Hu, Mu, Rt
Applications: ICC, IHC, IP, WB
BLMH/Bleomycin
Hydrolase Antibody
NBP1-88640
Western Blot BLMH/Bleomycin Hydrolase Antibody
Immunohistochemistry-Paraffin BLMH/Bleomycin Hydrolase Antibody
Immunohistochemistry-Paraffin BLMH/Bleomycin Hydrolase Antibody
Species: Hu, Mu, Rt
Applications: IHC, IHC-P, WB
GCHFR Antibody
(846011) [Unconjugate
MAB7918
Simple Western GCHFR Antibody (846011) [Unconjugated]
Western Blot GCHFR Antibody (846011) [Unconjugated]
Species: Hu
Applications: Simple Western, WB

epsilon-Sarcoglycan An
NBP1-59794
Immunohistochemistry epsilon-Sarcoglycan Antibody
Western Blot epsilon-Sarcoglycan Antibody
Western Blot epsilon-Sarcoglycan Antibody
Species: Hu, Mu
Applications: IHC, IHC-P, WB
QDPR Antibody
AF8038
Western Blot QDPR Antibody
Species: Hu, Mu, Rt
Applications: WB

Publications for GCH1 Antibody (NBP3-12307) (0)

There are no publications for GCH1 Antibody (NBP3-12307).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for GCH1 Antibody (NBP3-12307) (0)

There are no reviews for GCH1 Antibody (NBP3-12307). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for GCH1 Antibody (NBP3-12307) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional GCH1 Products

Blogs on GCH1

There are no specific blogs for GCH1, but you can read our latest blog posts.
Read our latest blog and use the new citation tool on bio-techne.com

Customers Who Bought This Also Bought

Contact Information

Product PDFs

  PDF Datasheet
  Request CofA
  Request SDS

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our GCH1 Antibody and receive a gift card or discount.


Bioinformatics

Gene Symbol GCH1