Name: FGFR2 Antibody (98707) [Unconjugated] - (IIIb)
Brand: Novus Biologicals
SKU: MAB665
Price: 559 USD

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Reactivity	HuSpecies Glossary
Applications	WB, B/N
Clone	98707
Clonality	Monoclonal
Host	Mouse
Conjugate	Unconjugated

Immunogen	Mouse myeloma cell line NS0-derived recombinant human FGF R2 isoforms and S. frugiperda insect ovarian cell line Sf 21-derived recombinant human FGF R2 isoforms
Specificity	Reacts with multiple isoforms of human FGF R2 although it shows a marked preference for human FGF R2 (IIIb) isoforms in some assays as described below. In direct ELISAs, displays a three-fold preference for FGF R2 (IIIb) isoforms over (IIIc) isoforms. Shows approximately 50% cross-reactivity with recombinant mouse (rm) FGF R2 isoforms and no cross-reactivity with any isoforms of recombinant human (rh) FGF R1 or rhFGF R3. In Western blots, shows approximately 25% cross-reactivity with rhFGF R2 (IIIc) isoforms, 100% cross-reactivity with all isoforms of rmFGF R2 and no cross-reactivity with any isoforms of rhFGF RI, rhFGF R3, or rhFGF R4. Neutralizes the bioactivity of rhFGF R2 (IIIb) isoforms.
Source	N/A
Isotype	IgG1
Clonality	Monoclonal
Host	Mouse
Gene	FGFR2
Purity Statement	Protein A or G purified from ascites
Endotoxin Note	<0.10 EU per 1 μg of the antibody by the LAL method.
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer	Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative	No Preservative
Reconstitution Instructions	Reconstitute at 0.5 mg/mL in sterile PBS.

Publications using MAB665	Applications	Species
Hwee Hui Lau, Nur Shabrina Amirruddin, Larry Sai Weng Loo, Jun Wei Chan, Elhadi Iich, Vidhya Gomathi Krishnan et al. FGFR-mediated ERK1/2 signaling contributes to mesendoderm and definitive endoderm formation in vitro iScience 8/18/2023 [PMID: 37502260]
DG Brownfield, AD de Arce, E Ghelfi, A Gillich, TJ Desai, MA Krasnow Alveolar cell fate selection and lifelong maintenance of AT2 cells by FGF signaling Nature Communications, 2022-11-21;13(1):7137. 2022-11-21 [PMID: 36414616] (IHC, Mouse)	IHC	Mouse
Andrea Hille, Susanne Grüger, Hans Christiansen, Hendrik A. Wolff, Beate Volkmer, Jörg Lehmann et al. Effect of tumour-cell-derived or recombinant keratinocyte growth factor (KGF) on proliferation and radioresponse of human epithelial tumour cells (HNSCC) and normal keratinocytes in vitro Radiation and Environmental Biophysics 5/1/2010 [PMID: 20213138]
Kosman J, Carmean N, Leaf EM, Dyamenahalli K, Bassuk JA Translocation of fibroblast growth factor-10 and its receptor into nuclei of human urothelial cells. J. Cell. Biochem., 2007-10-15;102(3):769-85. 2007-10-15 [PMID: 17471512] (ICC, Human)	ICC	Human

FGFR2 Antibody (98707) [Unconjugated] - (IIIb)

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Carrier Free MAB665-SP