FGFR2 alpha Antibody (98706) [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

FGF activity is mediated by a family of type I transmembrane tyrosine kinases, which undergo dimerization and autophosphorylation after ligand binding. Five distinct genes encode closely related FGF receptors, FGF R1 through 5. FGF Rs contain three Ig-like domains and a stretch of acidic residues between the first and second Ig-like domains. FGF R1, 2, 3, and -4 have a cytoplasmic split tyrosine-kinase domain, but FGF R5 does not. Multiple forms of FGF R1, 2, and 3 are generated by alternative splicing

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 5 applications: ICC/IF, IHC, IHC-P, Immunoprecipitation, Western Blot.

Showing Publications 1 - 5 of 5.

Publications using MAB6841	Applications	Species
T Shirakihar, H Yamaguchi, T Kondo, M Yashiro, R Sakai Transferrin receptor 1 promotes the fibroblast growth factor receptor-mediated oncogenic potential of diffused-type gastric cancer Oncogene, 2022-03-25;0(0):. 2022-03-25 [PMID: 35338344] (ICC/IF, Western Blot, Human)	ICC/IF, Western Blot	Human
N Schäfer, GH Gielen, L Rauschenba, S Kebir, A Till, R Reinartz, M Simon, P Niehusmann, C Kleinschni, U Herrlinger, T Pietsch, B Scheffler, M Glas Longitudinal heterogeneity in glioblastoma: moving targets in recurrent versus primary tumors J Transl Med, 2019-03-20;17(1):96. 2019-03-20 [PMID: 30894200] (IHC-P, Human)	IHC-P	Human
SY Kim, T Ahn, H Bang, JS Ham, J Kim, ST Kim, J Jang, M Shim, SY Kang, SH Park, BH Min, H Lee, WK Kang, KM Kim, W Park, J Lee Acquired resistance to LY2874455 in FGFR2-amplified gastric cancer through an emergence of novel FGFR2-ACSL5 fusion Oncotarget, 2017-02-28;8(9):15014-15022. 2017-02-28 [PMID: 28122360] (IHC-P, Human)	IHC-P	Human
Mathur , Anjili, Ware , Christop, Davis , Lenora, Gazdar , Adi, Pan , Bo-Sheng, Lutterbach , Bart FGFR2 is amplified in the NCI-H716 colorectal cancer cell line and is required for growth and survival. PLoS ONE, 2014-06-26;9(6):e98515. 2014-06-26 [PMID: 24968263] (IHC, Western Blot, Human)	IHC, Western Blot	Human
Kunii K, Davis L, Gorenstein J, Hatch H, Yashiro M, Di Bacco A, Elbi C, Lutterbach B FGFR2-amplified gastric cancer cell lines require FGFR2 and Erbb3 signaling for growth and survival. Cancer Res., 2008-04-01;68(7):2340-8. 2008-04-01 [PMID: 18381441] (Immunoprecipitation, Western Blot, Human)	Immunoprecipitation, Western Blot	Human

Array MAB6841

• FGFR2 alpha Antibodies
• FGFR2 alpha ELISA
• FGFR2 alpha Proteins and Enzymes