Home » FGF-6 » FGF-6 Antibodies » FGF-6 Antibody [Biotin]

FGF-6 Antibody [Biotin]

 (1 Publication)
 See All Related
Submit a Review

Images

 
There are currently no images for FGF-6 Antibody (BAF238).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA(Det)
Clonality
Polyclonal
Host
Goat
Conjugate
Biotin
Concentration
LYOPH

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Unconjugated
AF238
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
AF238
Carrier Free
AF238
Carrier Free
AF238-SP
Novus Biologicals offers 100% Guarantee

FGF-6 Antibody [Biotin] Summary

Immunogen
E. coli-derived recombinant human FGF-6 (R&D Systems, Catalog # 238-F6)
Gly41-Ile208
Accession # P10767
Specificity
Detects human FGF-6 in ELISAs and Western blots. In sandwich immunoassays, less than 5% cross-reactivity with recombinant human (rh) FGF-4 is observed and less than 0.6% cross-reactivity with rhFGF acidic, rhFGF basic, rhFGF-5, rhFGF-7, rhFGF-9, rhFGF-10, rhFGF-17, and rhFGF-19 is observed.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
FGF6
Purity Statement
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • ELISA Capture (Matched Antibody Pair) 2-8 ug/mL
  • ELISA Detection (Matched Antibody Pair) 0.1-0.4 ug/mL
  • ELISA Standard (Matched Pair)
  • Western Blot 0.1 ug/mL
Application Notes
ELISA Capture: Human FGF-6 Antibody (Catalog # MAB238)
ELISA Detection: Human FGF-6 Biotinylated Antibody (Catalog # BAF238)
Standard: Recombinant Human FGF-6 (Catalog # 238-F6)
Readout System
Publications
Read Publication using
BAF238 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for FGF-6 Antibody [Biotin]

  • FGF6
  • FGF-6
  • fibroblast growth factor 6
  • HBGF-6
  • Heparin secretory-transforming protein 2
  • Heparin-binding growth factor 6
  • HST2
  • HST-2
  • HSTF2
  • HSTF-2

Background

Fibroblast Growth Factor-6 (FGF-6), also known as HST-2, is a 25-28 kDa member of the FGF family of heparin binding polypeptides which are potent regulators of cell proliferation, differentiation, and function. FGF proteins contain a 120 amino acid (aa) core FGF domain that exhibits a beta -trefoil structure (1, 2). Mature human FGF-6 is a 171 aa protein that shares 94% aa sequence identity with mouse and rat FGF-6 (3). It binds and signals primarily through FGF R1c, 2c, and 4 (4). FGF-6 functions as a mitogen for fibroblasts, vascular endothelial cells, and prostate carcinoma cells, and N-linked glycosylation is required for the full mitogenic effect (5‑7). FGF-6 expression is restricted to skeletal muscle during development although it can be upregulated in prostate cancer and Kaposi sarcoma (7-9). In the adult, FGF-6 is upregulated in injured skeletal muscle and is required for muscle regeneration (10). FGF-6 inhibits the terminal differentiation of myoblasts and also cooperates with TGF-beta 2 to promote chondrogenesis in embryonic somites (8, 11).
  1. Wiedlocha, A. and V. Sorensen (2004) Curr. Top. Microbiol. Immunol. 286:45.
  2. Mohammadi, M. et al. (2005) Cytokine Growth Factor Rev. 16:107.
  3. Marics, I. et al. (1989) Oncogene 4:335.
  4. Ornitz, D.M. et al. (1996) J. Biol. Chem. 271:15292.
  5. Pizette, S. et al. (1991) Cell Growth Differ. 2:561.
  6. Asada, M. et al. (1999) Growth Factors 16:293.
  7. Ropiquet, F. et al. (2000) Cancer Res. 60:4245.
  8. de Lapeyriere, O. et al. (1993) Development 118:601.
  9. Li, J. et al. (1993) Cancer 72:2253.
  10. Floss, T. et al. (1997) Genes Dev. 11:2040.
  11. Grass, S. et al. (1996) Development 122:141.

    Limitations

    This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

    Customers Who Viewed This Item Also Viewed...

    FGF-4
    [Unconjugated]
    235-F4
    SDS-PAGE FGF-4 [Unconjugated]
    Bioactivity FGF-4 [Unconjugated]
    (76 Publications    )
    Species: Hu
    Applications: BA
    FGF
    basic/FGF2/bFGF [Unco
    233-FB
    FGF basic/FGF2/bFGF [Unconjugated]
    (559 Publications    )
    Species: Hu
    Applications: BA
    Sir2.1 Antibody
    NB100-1923
    Western Blot Sir2.1 Antibody
    (1 Review    )
    (2 Publications    )
    Species: Ce
    Applications: IHC, IHC-P, IP, WB
    FGFR4 Antibody
    (240929) [Unconjugate
    MAB6852
    Immunocytochemistry FGFR4 Antibody (240929) [Unconjugated]
    Immunohistochemistry FGFR4 Antibody (240929) [Unconjugated]
    Western Blot FGFR4 Antibody (240929) [Unconjugated]
    (2 Publications    )
    Species: Hu
    Applications: CyTOF-ready, Flow, ICC, IHC, WB
    FGF-3
    [Unconjugated]
    1206-F3
    FGF-3 [Unconjugated]
    (14 Publications    )
    Species: Hu
    Applications: BA
    FGF acidic/FGF1
    Antibody [Unconjugate
    AF232
    Immunohistochemistry FGF acidic/FGF1 Antibody [Unconjugated]
    Simple Western FGF acidic/FGF1 Antibody [Unconjugated]
    Western Blot FGF acidic/FGF1 Antibody [Unconjugated]
    (13 Publications    )
    Species: Hu
    Applications: IHC, Neut, Simple Western, WB
    KGF/FGF-7
    [Unconjugated]
    251-KG
    Bioactivity KGF/FGF-7 [Unconjugated]
    Bioactivity KGF/FGF-7 [Unconjugated]
    (85 Publications    )
    Species: Hu
    Applications: BA
    FGFR1 Antibody
    (M19B2) - BSA Free
    NB600-1287
    Flow Cytometry FGFR1 Antibody (M19B2) - BSA Free
    Flow Cytometry FGFR1 Antibody (M19B2) - BSA Free
    Western Blot FGFR1 Antibody (M19B2) - BSA Free
    (1 Review    )
    (7 Publications    )
    Species: Ca, Hu, Mu, Rb, Rt
    Applications: CyTOF-ready, Flow, ICC/IF, IHC, IHC-P, IP, WB
    Myogenin Antibody
    (671037)
    MAB66861
    Western Blot Myogenin Antibody (671037)
    Immunocytochemistry Myogenin Antibody (671037)
    (1 Review    )
    (3 Publications    )
    Species: Hu
    Applications: ICC, WB
    FGF-5 Antibody
    AF-237-NA
    Immunohistochemistry FGF-5 Antibody
    Neutralization FGF-5 Antibody
    (5 Publications    )
    Species: Hu
    Applications: IHC, Neut, WB
    FGFR2 Antibody
    (1G3)
    H00002263-M01
    Immunohistochemistry-Paraffin FGFR2 Antibody (1G3)
    Western Blot FGFR2 Antibody (1G3)
    Sandwich ELISA FGFR2 Antibody (1G3)
    (13 Publications    )
    Species: Bv, Hu
    Applications: ELISA, ICC/IF, IHC, IHC-P, S-ELISA, WB
    FGF-13 Antibody
    NBP2-16471
    Immunohistochemistry-Paraffin FGF-13 Antibody
    Western Blot FGF-13 Antibody
    Immunohistochemistry-Paraffin FGF-13 Antibody
    Species: Hu, Mu, Rt
    Applications: IHC, IHC-P, WB
    MYF-5 Antibody
    (OTI2G5)
    NBP2-44245
    Western Blot MYF-5 Antibody (OTI2G5)
    Immunohistochemistry-Paraffin MYF-5 Antibody (OTI2G5)
    Immunohistochemistry-Paraffin MYF-5 Antibody (OTI2G5)
    Species: Hu, Mu, Rt
    Applications: IHC, IHC-P, WB
    FGF-5 Antibody
    AF-237-NA
    Immunohistochemistry FGF-5 Antibody
    Neutralization FGF-5 Antibody
    (5 Publications    )
    Species: Hu
    Applications: IHC, Neut, WB
    FGF-8
    [Unconjugated]
    423-F8
    SDS-PAGE FGF-8 [Unconjugated]
    Bioactivity FGF-8 [Unconjugated]
    Cell Culture FGF-8 [Unconjugated]
    (1 Review    )
    (63 Publications    )
    Species: Hu, Mu
    Applications: BA
    Histatin 3
    Antibody (4G9)
    H00003347-M01
    Sandwich ELISA Histatin 3 Antibody (4G9)
    Immunocytochemistry/ Immunofluorescence Histatin 3 Antibody (4G9)
    (1 Publication    )
    Species: Hu
    Applications: ELISA, ICC/IF, S-ELISA, WB
    MyoD Antibody
    (5.8A) - BSA Free
    NB100-56511
    Immunocytochemistry/ Immunofluorescence MyoD Antibody (5.8A) - BSA Free
    Immunocytochemistry/ Immunofluorescence MyoD Antibody (5.8A) - BSA Free
    Western Blot MyoD Antibody (5.8A) - BSA Free
    (2 Reviews    )
    (27 Publications    )
    Species: Hu, Mu
    Applications: Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, KD, KO, WB
    Cytosolic
    Sulfotransferase 2A1/ ...
    AF5828
    Immunocytochemistry Cytosolic Sulfotransferase 2A1/SULT2A1 Antibody
    Western Blot Cytosolic Sulfotransferase 2A1/SULT2A1 Antibody
    Species: Hu
    Applications: ICC, Neut, WB
    FGFR3 Antibody
    (136312) [Unconjugate ...
    MAB7662
    Immunohistochemistry FGFR3 Antibody (136312) [Unconjugated] - (IIIc)
    Flow Cytometry FGFR3 Antibody (136312) [Unconjugated] - (IIIc)
    Immunocytochemistry FGFR3 Antibody (136312) [Unconjugated] - (IIIc)
    (1 Review    )
    (3 Publications    )
    Species: Hu
    Applications: Flow, ICC, IHC, WB
    FGF-6 Antibody
    [Biotin]
    BAF238
    FGF-6 Antibody [Biotin]
    Species: Hu
    Applications: WB, ELISA(Det)

    Publications for FGF-6 Antibody (BAF238)(1)

    We have publications tested in 1 confirmed species: Human.

    We have publications tested in 1 application: ELISA Development.


    Filter By Application
    ELISA Development
    (1)
    All Applications
    Filter By Species
    Human
    (1)
    All Species

    Reviews for FGF-6 Antibody (BAF238) (0)

    There are no reviews for FGF-6 Antibody (BAF238). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
    • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
    • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

    Product General Protocols

    Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

    Video Protocols

    WB Video Protocol

    FAQs for FGF-6 Antibody (BAF238) (0)

    There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

    Secondary Antibodies

    		 

    Isotype Controls

    Additional FGF-6 Products

    Blogs on FGF-6

    There are no specific blogs for FGF-6, but you can read our latest blog posts.
    Read our latest blog and use the new citation tool on bio-techne.com

    Customers Who Bought This Also Bought

    Contact Information

    Product PDFs

      PDF SDS
      PDF Datasheet
      Request CofA

    Calculators

    Concentration Calculator

    The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

    =
    ÷

    Review this Product

    Be the first to review our FGF-6 Antibody [Biotin] and receive a gift card or discount.


    Bioinformatics

    Gene Symbol FGF6
    Uniprot