Feline IL-4 DuoSet ELISA, 15 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

IL-4 (Interleukin-4) is a cytokine that is primarily expressed by Th2-biased CD4+ T cells, mast cells, basophils, and eosinophils. It promotes cell proliferation, survival, and immunoglobulin class switch to IgG4 and IgE in human B cells, acquisition of the Th2 phenotype by naïve CD4+ T cells, priming and chemotaxis of mast cells, eosinophils, and basophils, and the proliferation and activation of epithelial cells. IL-4 plays a dominant role in the development of allergic inflammation and asthma. The type I receptor for IL-4, which is expressed on hematopoietic cells, is a heterodimer of the ligand binding IL-4 R? and the common ? chain (a shared subunit of the receptors for IL-2, -7, -9, -15, and -21). The type II receptor on nonhematopoietic cells consists of IL-4 R? and IL-13 R?1. The type II receptor also transduces IL-13 mediated signals.

We have publications tested in 1 confirmed species: Feline.

Showing Publications 1 - 2 of 2.

Publications using DY984	Applications	Species
Declue AE, Schooley E, Nafe LA, Reinero CR feG-COOH blunts eosinophilic airway inflammation in a feline model of allergic asthma. Inflamm. Res., 2009-03-03;58(8):457-62. 2009-03-03 [PMID: 19255722] (Feline)		Feline
McEachern JA, Bingham J, Crameri G, Green DJ, Hancock TJ, Middleton D, Feng YR, Broder CC, Wang LF, Bossart KN A recombinant subunit vaccine formulation protects against lethal Nipah virus challenge in cats. Vaccine, 2008-06-02;26(31):3842-52. 2008-06-02 [PMID: 18556094] (Feline)		Feline

Array DY984

• IL-4 Antibodies
• IL-4 ELISA Kits
• IL-4 Kit
• IL-4 Proteins
• IL-4 Proteins and Enzymes
• IL-4 ELISAs