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Fc gamma RIIIB/CD16b Antibody (C1)

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Immunocytochemistry /Immunofluorescence: Fc gamma RIIIB/CD16b Antibody (C1) [NBP3-41587] - FITC staining on IF; Sample: Human U2OS cell; Primary Ab: 30ug/ml NBP3-41587; Second Ab: 5ug/ml FITC-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
Immunocytochemistry /Immunofluorescence: Fc gamma RIIIB/CD16b Antibody (C1) [NBP3-41587] - FITC staining on IF; Sample: Human U2OS cell; Primary Ab: 30ug/ml NBP3-41587; Second Ab: 5ug/ml FITC-Linked Caprine Anti-Mouse ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF, IHC
Clone
C1
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1 mg/ml

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Fc gamma RIIIB/CD16b Antibody (C1) Summary

Immunogen
Immunized with Human Fc gamma RIIIB/CD16b (Uniprot#: O75015; Immunogen sequence: Pro24-Ser203 (Uniprot#: O75015)
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
FCGR3B
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 5-20ug/mL
  • Immunohistochemistry 5-20ug/mL
  • Western Blot 0.5-2ug/mL

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
0.01M PBS, pH7.4, 50% glycerol
Preservative
0.05% Proclin 300
Concentration
1 mg/ml
Purity
Protein A or G purified

Alternate Names for Fc gamma RIIIB/CD16b Antibody (C1)

  • CD16
  • CD16b antigen
  • CD16b
  • Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
  • Fc fragment of IgG, low affinity IIIb, receptor for (CD16)
  • Fc gamma RIIIB
  • FCG3
  • Fc-gamma receptor IIIb (CD 16)
  • Fc-gamma RIII
  • Fc-gamma RIIIb
  • Fc-gamma RIII-beta
  • FCGR3
  • FCGR3B
  • FcgRIIIB
  • FcR-10
  • fcRIII
  • FCRIIIB
  • IGFR3
  • IgG Fc receptor III-1
  • low affinity immunoglobulin gamma Fc region receptor III-B

Background

CD16 (FcgRIII) is a 50-65 kDa glycoprotein serving as a low affinity IgG receptor. Human FcgRIII is expressed in two forms FcgRIII-A and -B. FcgRIII-A is a transmembrane protein of monocytes, macrophages, NK cells and a subset of T cells. It is associated with FceRI-g subunit and is responsible for antibody-dependent NK cell cytotoxicity. Mast cell FcgRIII-A is associated, moreover, with FceRI-b subunit. Besides IgG, FceRI-A can be triggered also by oligomeric IgE. FcgRIII-B is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a proadhesive phenotype.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol FCGR3B