Reactivity | Hu, Pm, Pm, Pm-Cm, RMSpecies Glossary |
Applications | Flow, ICC/IF, IHC, IP, B/N |
Clone | 3G8 |
Clonality | Monoclonal |
Host | Rabbit |
Conjugate | Janelia Fluor 646 |
Additional Information | Recombinant Monoclonal Antibody |
Immunogen | Human PMN (polymorphonuclear leukocytes) cells. |
Specificity | This antibody binds to CD16 at an epitope which is not the IgG-binding site. This antibody cannot distinguish between CD16a transmembrane isoform found on the surface of NK cells and macrophages (which can trigger the cytolytic response), and the GPI-linked CD16b isoform present on neutrophils or soluble CD16 found in the plasma. CD16 is the low affinity IgG receptor III and binds to aggregated IgG or IgG-antigen complex which functions in NK cell activation, phagocytosis and ADCC (antibody-dependent cell-mediated cytotoxicity). |
Isotype | IgG Kappa |
Clonality | Monoclonal |
Host | Rabbit |
Gene | FCGR3A |
Purity | Protein A purified |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Dilutions |
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Application Notes | Optimal dilution of this antibody should be experimentally determined. |
Storage | Store at 4C in the dark. |
Buffer | 50mM Sodium Borate |
Preservative | 0.05% Sodium Azide |
Purity | Protein A purified |
Secondary Antibodies |
Isotype Controls |
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Gene Symbol | FCGR3A |