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Fc gamma RII/CD32 Antibody (190723) [Unconjugated]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, CyTOF-ready
Clone
190723
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB1330U-100UG
Alexa Fluor 405
FAB1330V-100UG
Alexa Fluor 488
FAB1330G-100UG
Alexa Fluor 532
FAB1330X
Alexa Fluor 594
FAB1330T-100UG
Alexa Fluor 647
FAB1330R-100UG
Alexa Fluor 700
FAB1330N-100UG
Alexa Fluor 750
FAB1330S-100UG
Allophycocyanin
FAB1330A
Allophycocyanin/Cy7
FAB1330APCCY7
Biotin
FAB1330B
CoraFluor 1
FAB1330CL1
DyLight 350
FAB1330D
DyLight 405
FAB1330E
DyLight 488
FAB1330K
DyLight 550
FAB1330L
DyLight 594
FAB1330M
DyLight 650
FAB1330W
DyLight 680
FAB1330Y
DyLight 755
FAB1330Z
FITC
FAB1330F
HRP
FAB1330H
Janelia Fluor 525
FAB1330JF525
Janelia Fluor 549
FAB1330I
Janelia Fluor 646
FAB1330J
Janelia Fluor 669
FAB1330JF669
PE/Atto594
FAB1330PEATT594
PE/Cy5.5
FAB1330PECY55
PE/Cy7
FAB1330PECY7
PerCP
FAB1330C
Phycoerythrin
FAB1330P
mFluor Violet 450 SE
FAB1330MFV450
mFluor Violet 500 SE
FAB1330MFV500
mFluor Violet 610 SE
FAB1330MFV610
View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
FAB1330A
Carrier Free
FAB1330P
Carrier Free
MAB1330-SP
Carrier Free
MAB1330-500
Carrier Free
FAB1330V-100UG
Carrier Free
FAB1330U-100UG
Carrier Free
FAB1330T-100UG
Carrier Free
FAB1330S-100UG
Carrier Free
FAB1330R-100UG
Carrier Free
FAB1330N-100UG
Carrier Free
FAB1330G-100UG
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Fc gamma RII/CD32 Antibody (190723) [Unconjugated] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human Fc gamma RIIB
Ala46-Pro217
Accession # P31994
Specificity
Detects human Fc gamma RIIA and human Fc gamma RIIB in direct ELISAs and Western blots. In direct ELISAs and Western blots, this antibody does not cross-react with recombinant mouse Fc gamma  RII.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
FCGR2A
Purity Statement
Protein A or G purified from hybridoma culture supernatant
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry 2.5 ug/10^6 cells
  • Western Blot 1 ug/mL
Publications
Read Publications using
MAB1330 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Fc gamma RII/CD32 Antibody (190723) [Unconjugated]

  • CD32 antigen
  • CD32B
  • CD32Fc fragment of IgG, low affinity II, receptor for (CD32)
  • CDw32
  • Fc fragment of IgG, low affinity IIb, receptor (CD32)
  • Fc fragment of IgG, low affinity IIb, receptor for (CD32)
  • Fc gamma RII
  • Fc gamma RIIb
  • FCG2
  • Fc-gamma RII-b
  • FcgammaRIIb
  • fc-gamma-RIIb
  • FCGR2
  • FcgRII
  • FcgRIIB
  • fcRII-b
  • FcRII-c
  • IGFR2
  • IgG Fc receptor II-b
  • low affinity immunoglobulin gamma Fc region receptor II-b

Background

Fc gamma RII, also known as CD32, is a group of three closely related proteins (Fc gamma RIIA, Fc gamma RIIB, Fc gamma RIIC) that share greater than 94% amino acid identity in their extracellular domains. They function as transmembrane receptors for the Fc portion of IgG molecules. These proteins are expressed by various hematopoietic cells including monocytes, macrophages, neutrophils, NK, T cells, and B cells. The Fc gamma RII proteins are involved in phagocytosis of immune complexes and modulation of antibody production by B cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Fc gamma RII/CD32 Antibody (MAB1330)(3)

We have publications tested in 2 confirmed species: Human, Canine.

We have publications tested in 3 applications: ELISA Development, ICC, Western Blot.


Filter By Application
ELISA Development
(1)
ICC
(1)
Western Blot
(1)
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Human
(2)
Canine
(1)
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Bioinformatics

Gene Symbol FCGR2A
Uniprot