FABP5/E-FABP Antibody [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

FABP5, also known as epidermal fatty acid binding protein (E-FABP), is a 15 kDa member of a cytosolic fatty acid binding protein superfamily. It is associated with keratinocytes and adipocytes and is suggested to promote fatty acid availability to enzymes, protect cell structures from fatty acid attack, and target fatty acids to nuclear transcription factors. The amino acid sequence of human FABP5 is 80%, 81% and 92% identical to that of mouse, rat and bovine FABP5, respectively.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 4 confirmed species: Human, Mouse, Rat, Transgenic Mouse.

We have publications tested in 7 applications: Flow Cytometry, ICC, IHC, IHC-Fr, IHC-P, Immunohistochemistry, Western Blot.

Showing Publications 1 - 10 of 24. Show All 24 Publications. Collapse Publications.

Publications using AF1476	Applications	Species
Kjar, A;Haschert, MR;Zepeda, JC;Simmons, AJ;Yates, A;Chavarria, D;Fernandez, M;Robertson, G;Abdulrahman, AM;Kim, H;Marguerite, NT;Moen, RK;Drake, LE;Curry, CW;O'Grady, BJ;Gama, V;Lau, KS;Grueter, B;Brunger, JM;Lippmann, ES; Biofunctionalized gelatin hydrogels support development and maturation of iPSC-derived cortical organoids Cell reports 2024-10-17 [PMID: 39423129] (Immunohistochemistry, Human)	Immunohistochemistry	Human
Zhong, D;Chen, J;Qiao, R;Song, C;Hao, C;Zou, Y;Bai, M;Su, W;Yang, B;Sun, D;Jia, Z;Sun, Y; Genetic or pharmacologic blockade of mPGES-2 attenuates renal lipotoxicity and diabetic kidney disease by targeting Rev-Erb?/FABP5 signaling Cell reports 2024-04-06 [PMID: 38583151] (Immunohistochemistry, Mouse, Transgenic Mouse)	Immunohistochemistry	Mouse, Transgenic Mouse
Hwang, SM;Awasthi, D;Jeong, J;Sandoval, TA;Chae, CS;Ramos, Y;Tan, C;Falco, MM;McBain, IT;Mishra, B;Ivashkiv, LB;Zamarin, D;Cantillo, E;Chapman-Davis, E;Holcomb, K;Morales, DK;Rodriguez, PC;Conejo-Garcia, JR;Kaczocha, M;Vähärautio, A;Song, M;Cubillos-Ruiz, JR; Transgelin 2 guards T cell lipid metabolic programming and anti-tumor function Research square 2023-12-14 [PMID: 38168227] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
M Fauzan, S Oubraim, M Yu, ST Glaser, M Kaczocha, S Haj-Dahman Fatty Acid-Binding Protein 5 Modulates Brain Endocannabinoid Tone and Retrograde Signaling in the Striatum Frontiers in Cellular Neuroscience, 2022-07-07;16(0):936939. 2022-07-07 [PMID: 35875351] (IHC, Mouse)	IHC	Mouse
DM Bogdan, K Studholme, A DiBua, C Gordon, MP Kanjiya, M Yu, M Puopolo, M Kaczocha FABP5 deletion in nociceptors augments endocannabinoid signaling and suppresses TRPV1 sensitization and inflammatory pain Oncogene, 2022-06-02;12(1):9241. 2022-06-02 [PMID: 35655086] (IHC, Mouse)	IHC	Mouse
C Beuker, D Schafflick, JK Strecker, M Heming, X Li, J Wolbert, A Schmidt-Po, C Thomas, T Kuhlmann, I Aranda-Par, N A-Gonzalez, PA Kumar, Y Werner, E Kilic, DM Hermann, H Wiendl, R Stumm, GMZ Hörste, J Minnerup Stroke induces disease-specific myeloid cells in the brain parenchyma and pia Nature Communications, 2022-02-17;13(1):945. 2022-02-17 [PMID: 35177618] (IHC, Human, Mouse)	IHC	Human, Mouse
Y Li, S Wang, Z Xing, Y Niu, Z Liao, Y Lu, J Qiu, J Zhang, C Wang, L Dong Destructing biofilms by cationic dextran through phase transition Carbohydrate polymers, 2021-10-23;279(0):118778. 2021-10-23 [PMID: 34980345] (IHC, Mouse)	IHC	Mouse
Di Yin, Jiaqing Hao, Rong Jin, Yanmei Yi, Sobha R. Bodduluri, Yuan Hua et al. Epidermal Fatty Acid‒Binding Protein Mediates Depilatory-Induced Acute Skin Inflammation Journal of Investigative Dermatology 2022-07-01 [PMID: 34942197]
Bénédicte Oulès, Emanuel Rognoni, Esther Hoste, Georgina Goss, Ryan Fiehler, Ken Natsuga et al. Mutant Lef1 controls Gata6 in sebaceous gland development and cancer The EMBO Journal 2019-05-02 [PMID: 30886049]
Francesco Napoletano, Olga Baron, Peter Vandenabeele, Bertrand Mollereau, Manolis Fanto Intersections between Regulated Cell Death and Autophagy Trends in Cell Biology 2019-04-01 [PMID: 30665736]
Austin Moore, Linwei Wu, Jen‐Chieh Chuang, Xuxu Sun, Xin Luo, Purva Gopal et al. Arid1a Loss Drives Nonalcoholic Steatohepatitis in Mice Through Epigenetic Dysregulation of Hepatic Lipogenesis and Fatty Acid Oxidation Hepatology 2019-05-01 [PMID: 30584660]
K Singh, E Camera, L Krug, A Basu, RK Pandey, S Munir, M Wlaschek, S Kochanek, M Schorpp-Ki, M Picardo, P Angel, C Niemann, P Maity, K Scharffett JunB defines functional and structural integrity of the epidermo-pilosebaceous unit in the skin Nat Commun, 2018-08-24;9(1):3425. 2018-08-24 [PMID: 30143626] (IHC-P, Mouse)	IHC-P	Mouse
Yuwen Zhang, Jiaqing Hao, Jun Zeng, Qiang Li, Enyu Rao, Yanwen Sun et al. Epidermal fatty acid binding protein prevents chemical-induced skin tumorigenesis by regulation of TPA-induced IFN/p53/SOX2 pathway in keratinocytes Journal of Investigative Dermatology 2018-09-01 [PMID: 29559340]
J Lambertz, T Berger, TW Mak, J van Helden, R Weiskirche Lipocalin-2 in Fructose-Induced Fatty Liver Disease Front Physiol, 2017-11-28;8(0):964. 11/28/2017 [PMID: 29234288]
Yuwen Zhang Adipose Fatty Acid Binding Protein Promotes Saturated Fatty Acid-Induced Macrophage Cell Death through Enhancing Ceramide Production J. Immunol, 2016-12-05;0(0):. 2016-12-05 [PMID: 27920274] (Western Blot, Mouse)	Western Blot	Mouse
Liraz Levi, Zeneng Wang, Mary Kathryn Doud, Stanley L. Hazen, Noa Noy Saturated fatty acids regulate retinoic acid signalling and suppress tumorigenesis by targeting fatty acid-binding protein 5 Nature Communications 2015-11-23 [PMID: 26592976]
Wei Zhang, Liraz Levi, Pallab Banerjee, Mukesh Jain, Noa Noy Kruppel-like factor 2 suppresses mammary carcinoma growth by regulating retinoic acid signaling Oncotarget 2015-09-21 [PMID: 26416422]
Kretzschmar K, Cottle D, Donati G, Chiang M, Quist S, Gollnick H, Natsuga K, Lin K, Watt F BLIMP1 is required for postnatal epidermal homeostasis but does not define a sebaceous gland progenitor under steady-state conditions. Stem Cell Reports, 2014-09-18;3(4):620-33. 2014-09-18 [PMID: 25358790] (IHC, Rat)	IHC	Rat
Zhang Y, Sun Y, Rao E, Yan F, Li Q, Zhang Y, Silverstein K, Liu S, Sauter E, Cleary M, Li B Fatty acid-binding protein E-FABP restricts tumor growth by promoting IFN-beta responses in tumor-associated macrophages. Cancer Res, 2014-04-08;74(11):2986-98. 2014-04-08 [PMID: 24713431] (IHC, Western Blot, Mouse)	IHC, Western Blot	Mouse
Yu S, Levi L, Casadesus G, Kunos G, Noy N Fatty acid-binding protein 5 (FABP5) regulates cognitive function both by decreasing anandamide levels and by activating the nuclear receptor peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) in the brain. J Biol Chem, 2014-03-18;289(18):12748-58. 2014-03-18 [PMID: 24644281] (Western Blot, Mouse)	Western Blot	Mouse
Yu S, Levi L, Siegel R, Noy N Retinoic acid induces neurogenesis by activating both retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta). J Biol Chem, 2012-10-26;287(50):42195-205. 2012-10-26 [PMID: 23105114] (ICC, IHC-Fr, Western Blot, Mouse)	ICC, IHC-Fr, Western Blot	Mouse
Li C, Wang W, Wang H, Zhong Y, Di J, Lin Y Proteomic analysis of proteins differentially expressed in uterine lymphocytes obtained from wild-type and NOD mice. J. Cell. Biochem., 2009-10-01;108(2):447-57. 2009-10-01 [PMID: 19623579] (Western Blot, Mouse)	Western Blot	Mouse
Berry DC, Noy N All-trans-retinoic acid represses obesity and insulin resistance by activating both peroxisome proliferation-activated receptor beta/delta and retinoic acid receptor. Mol. Cell. Biol., 2009-04-13;29(12):3286-96. 2009-04-13 [PMID: 19364826] (Western Blot, Mouse)	Western Blot	Mouse
Witting SR, Brown M, Saxena R, Nabinger S, Morral N Helper-dependent adenovirus-mediated short hairpin RNA expression in the liver activates the interferon response. J. Biol. Chem., 2007-11-19;283(4):2120-8. 2007-11-19 [PMID: 18025090] (Western Blot, Mouse)	Western Blot	Mouse
Show All 24 Publications. Collapse Publications.

Array AF1476

• FABP5/E-FABP Antibodies
• FABP5/E-FABP ELISA Kits
• FABP5/E-FABP Lysate
• FABP5/E-FABP Protein
• FABP5/E-FABP Proteins and Enzymes