ER alpha/NR3A1 Antibody

Estrogen receptor alpha (ER alpha) is a nuclear protein and member of the steroid hormone receptor family. ER alpha possesses both DNA binding and ligand binding domains, and exerts a significant role in activating the transcription of certain genes (1). Ligand-dependent dimerization and phosphorylation on serines, 104, 106, and 118 function to regulate the transcriptional activation of ER alpha (2). The phosphorylation of the human estrogen receptor (ER) serine residue at position 118 is required for full activity of the ER activation function 1 (AF-1) (3).

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: Immunoprecipitation, WB.

Showing Publications 1 - 3 of 3.

Publications using NBP1-84827	Applications	Species
Oelschl�ger L, Stahl P, Kaschani F et al. Taspase1 Facilitates Topoisomerase II?-Mediated DNA Double-Strand Breaks Driving Estrogen-Induced Transcription Cells 2023-01-18 [PMID: 36766705] (Immunoprecipitation)	Immunoprecipitation
Torres-Lopez L, Maycotte P, Linan-Rico A et al. Tamoxifen induces toxicity, causes autophagy, and partially reverses dexamethasone resistance in Jurkat T cells J Leukoc Biol 2019-01-16 [PMID: 30645008] (WB, Human)	WB	Human
Algenas C, Agaton C, Fagerberg L et al. Antibody performance in western blot applications is context-dependent. Biotechnol J 2014-03-01 [PMID: 24403002]

Array NBP1-84827

• ER alpha/NR3A1 Antibodies
• ER alpha/NR3A1 Lysates
• ER alpha/NR3A1 Proteins
• ER alpha/NR3A1 ELISA